Venous Ethanol for Ventricular Tachycardia

Part of paid clinical trials in Houston, Texas.

Sponsor
The Methodist Hospital Research Institute
Study ID
NCT05511246
Phase
PHASE2
Status
Recruiting
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Conditions

  • Ischemic Cardiomyopathy
  • Ventricular Tachycardia

Eligibility Criteria

Sex
ALL
Age
18 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

  • Venous ethanol — DRUG
    Cannulation of coronary vein or veins in the VT substrate and balloon injection of ethanol
  • Catheter ablation — PROCEDURE
    Endocardial catheter ablation of VT substrate

Study Details

Comparative effectiveness randomized clinical trial, comparing endocardial radiofrequency ablation alone vs radiofrequency ablation combined with venous ethanol in patients with ischemic ventricular tachycardia -Venous Ethanol for Left Ventricular Ischemic Ventricular Tachycardia -VELVET clinical trial

Key Dates

First listed
Aug 22, 2022
Start date
Apr 12, 2023
Status verified
Mar 2026
Primary completion
Dec 12, 2027
Completion
Dec 12, 2028

Study Design

Enrollment
156 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Control
    Endocardial radiofrequency ablation of ventricular tachycardia
  • Experimental: Venous ethanol
    Endocardial radiofrequency ablation of ventricular tachycardia combined with venous ethanol ablation of the tachycardia substrate

Primary Outcome Measure

Ventricular tachycardia recurrence [ Time Frame: 0-12 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Houston Methodist HospitalHoustonTexas77030
Chinwe Ngumezi, RN
[email protected]
346-238-0290
Iris Melissa Alanis
[email protected]
7134416548
Miguel Valderrabano, MD (PRINCIPAL_INVESTIGATOR)

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Houston Methodist Hospital· Houston, TX

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