Sperm Preparation Prior to Intrauterine Insemination Study

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT05693220
Status
Recruiting
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Conditions

  • Anovulation
  • Fertility Disorders
  • Infertility
  • Infertility Secondary
  • Infertility Unexplained
  • Reproductive Issues

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Zymot Multi sperm separation device — DEVICE
    Sperm preparation with Zymot Multi sperm preparation device
  • Density gradient centrifugation — OTHER
    Sperm preparation with density gradient centrifugation

Study Details

This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.

Key Dates

First listed
Jan 20, 2023
Start date
Feb 5, 2023
Status verified
Sep 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
270 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Density gradient centrifugation
    Patients will undergo sperm preparation by density gradient centrifugation
  • Active Comparator: Zymot sperm separation device
    Patients will undergo sperm preparation by the Zymot sperm separation device

Primary Outcome Measure

Cumulative clinical pregnancy rate [ Time Frame: 3 treatment cycles, an average of 5 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UCSF Center for Reproductive HealthSan FranciscoCalifornia94158
Alisha T Tolani, MD
[email protected]
628-286-7307
Elena Hoskin
[email protected]
Alisha T Tolani, MD (PRINCIPAL_INVESTIGATOR)
Mitchell Rosen, MD (PRINCIPAL_INVESTIGATOR)

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By research site
UCSF Center for Reproductive Health· San Francisco, CA

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