Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD

Part of paid clinical trials in The Bronx, New York.

Sponsor
Montefiore Medical Center
Study ID
NCT05929911
Status
Recruiting
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Conditions

  • HIV
  • Post Traumatic Stress Disorder (PTSD)

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Trauma-focused psychodynamic psychotherapy — BEHAVIORAL
    This psychotherapy addresses disruptions in the ability to reflect and affective regulation by exploring the psychological meanings of symptoms and their relation to traumatic events. The therapist works to identify intrapsychic conflicts, intense negative affects, and defense mechanisms related to the PTSD syndrome using a psychodynamic formulation that provides a framework for intervention. The transference provides a forum for patients to address feelings of mistrust, difficulties with authority, fears of abuse, angry and guilty feelings, and fantasies. This treatment will be provided in-person or over teletherapy as the public health situation demands.

Study Details

People living with HIV (PLWH) have a higher rate of post-traumatic stress disorder (PTSD) diagnosis than the general population. Comorbid PTSD is also associated with negative HIV-related health outcomes. Unfortunately, little outcome research has examined the usefulness of PTSD treatments for PTSD. This pilot study adapts for PLWH a non-exposure based psychotherapy for PTSD focused on reflecting on one's emotions and relationships and understanding and working through how trauma may have disrupted them. The study team is interested in better understanding the needs of PLWH with PTSD, learning whether PLWH with PTSD find this treatment acceptable and helpful, and beginning to understand the relationship between HIV-related health factors (e.g., inflammation and stress biology) and PTSD, and how these health factors may improve during treatment.

Key Dates

First listed
Jul 3, 2023
Start date
Apr 26, 2024
Status verified
Jun 2026
Primary completion
Jun 30, 2027
Completion
Jun 30, 2027

Study Design

Enrollment
20 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Trauma-focused psychodynamic psychotherapy
    Twice-weekly psychotherapy for 24 sessions

Primary Outcome Measure

Change in PTSD Score based on the Clinician Administered PTSD Scale for DSM-5 [ Time Frame: Baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Albert Einstein College of MedicineThe BronxNew York10461
John R Keefe, PhD
[email protected]
347-391-4189
Barbara L Milrod, MD
[email protected]
Barbara L Milrod, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in The Bronx, NY

By condition
HIV
By specialty
Infectious disease
By research site
Albert Einstein College of Medicine· The Bronx, NY

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