A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis

Part of paid clinical trials in Birmingham, Alabama.

Sponsor
Bristol-Myers Squibb
Study ID
NCT06003426
Phase
PHASE3
Status
Active Not Recruiting

Conditions

  • Idiopathic Pulmonary Fibrosis

Eligibility Criteria

Sex
ALL
Age
40 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • BMS-986278 — DRUG
    Specified dose on specified days
  • BMS-986278 Placebo — DRUG
    Specified dose on specified days

Study Details

The purpose of this study is to evaluate the efficacy, safety, and tolerability of BMS-986278 in participants with Idiopathic Pulmonary Fibrosis.

Key Dates

Start date
Sep 14, 2023
Status verified
Mar 2026
Primary completion
Oct 6, 2026
Completion
Jun 4, 2027

Study Design

Enrollment
1,255 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: BMS-986278 Dose 1
  • Experimental: BMS-986278 Dose 2
  • Placebo Comparator: BMS-986278 Placebo

Primary Outcome Measure

Number of participants that experience spontaneous syncopal events [ Time Frame: At approximately 4 weeks ]

Locations (70)

FacilityCityStateZIPSite coordinators
Local Institution - 0189BirminghamAlabama35294-
Local Institution - 0361PhoenixArizona85013-4220-
Local Institution - 0396La JollaCalifornia92037-1027-
Local Institution - 0193Los AngelesCalifornia90033-5313-
Local Institution - 0398Los AngelesCalifornia90095-3075-
Local Institution - 0389OrangeCalifornia92868-3201-
Local Institution - 0405SacramentoCalifornia95817-
Local Institution - 0185San FranciscoCalifornia94143-2202-
Local Institution - 0186StanfordCalifornia94305-
Local Institution - 0363AuroraColorado80045-
Local Institution - 0194DenverColorado80206-
Local Institution - 0175New HavenConnecticut06510-
Local Institution - 0151NewarkDelaware19713-1337-
Local Institution - 0367Washington D.C.District of Columbia20007-2113-
Local Institution - 0101BrandonFlorida33511-5706-
Local Institution - 0436ClearwaterFlorida33765-
Local Institution - 0425DeBaryFlorida32713-1817-
Local Institution - 0079GainesvilleFlorida32610-
Local Institution - 0352HialeahFlorida33016-
Local Institution - 0370KissimmeeFlorida34746-4654-
Local Institution - 0502LeesburgFlorida34748-5077-
Local Institution - 0153Loxahatchee GrovesFlorida33411-
Local Institution - 0187OcalaFlorida34471-
Local Institution - 0418PensacolaFlorida32503-2670-
Local Institution - 0206St. PetersburgFlorida33704-
Local Institution - 0364TampaFlorida33606-
Local Institution - 0372DublinGeorgia31021-2561-
Local Institution - 0058ChicagoIllinois60637-
Local Institution - 0178ChicagoIllinois60611-
Local Institution - 0183ChicagoIllinois60612-3841-
Local Institution - 0085MaywoodIllinois60153-3328-
Local Institution - 0325PeoriaIllinois61637-0001-
Local Institution - 0180Iowa CityIowa522242-1009-
Local Institution - 0204Kansas CityKansas66160-
Local Institution - 0393LouisvilleKentucky40202-1332-
Local Institution - 0354BaltimoreMaryland21201-1544-
Local Institution - 0040BostonMassachusetts02135-2907-
Local Institution - 0380BostonMassachusetts02114-
Local Institution - 0472Ann ArborMichigan48109-5000-
Local Institution - 0096ChesterfieldMissouri63017-3425-
Local Institution - 0174St LouisMissouri63110-1010-
Local Institution - 0154Mount KiscoNew York10549-3417-
Local Institution - 0433DurhamNorth Carolina27710-
Local Institution - 0366WilmingtonNorth Carolina28412-
Local Institution - 0368Winston-SalemNorth Carolina27103-
Local Institution - 0201CincinnatiOhio45267-0595-
Local Institution - 0197ColumbusOhio43201-
Local Institution - 0417ToledoOhio43608-2603-
Local Institution - 0181Oklahoma CityOklahoma73104-5417-
Local Institution - 0373TulsaOklahoma74133-
Local Institution - 0021PortlandOregon97239-3011-
Local Institution - 0067HersheyPennsylvania17033-2360-
Local Institution - 0199PhiladelphiaPennsylvania19140-5103-
Local Institution - 0388PhiladelphiaPennsylvania19107-5109-
Local Institution - 0406PhiladelphiaPennsylvania19104-5161-
Local Institution - 0202PittsburghPennsylvania15213-
Local Institution - 0346WynnewoodPennsylvania19096-3432-
Local Institution - 0375AndersonSouth Carolina29621-
Local Institution - 0188CharlestonSouth Carolina29425-
Local Institution - 0400NashvilleTennessee37204-
Local Institution - 0073DallasTexas75235-5351-
Local Institution - 0377DallasTexas75245-2017-
Local Institution - 0039HoustonTexas77030-4202-
Local Institution - 0097HoustonTexas77030-
Local Institution - 0029McKinneyTexas75069-
Local Institution - 0048San AntonioTexas78229-4404-
Local Institution - 0027Salt Lake CityUtah84108-
Local Institution - 0184RichmondVirginia23298-
Local Institution - 0191EverettWashington98208-6526-
Local Institution - 0362SeattleWashington98195-

Find similar trials in Birmingham, AL

By research site
Local Institution - 0189· Birmingham, ALLocal Institution - 0361· Phoenix, AZLocal Institution - 0396· La Jolla, CALocal Institution - 0193· Los Angeles, CALocal Institution - 0398· Los Angeles, CALocal Institution - 0389· Orange, CA

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