Topical CBD Scar Healing Study

Part of paid clinical trials in Oklahoma City, Oklahoma.

Sponsor
University of Oklahoma
Study ID
NCT06129591
Phase
PHASE1
Status
Recruiting
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Conditions

  • Paramedian Forehead Flap

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Vantage Hemp CBD Isolate + Silicone patch — DRUG
    The study intervention is prospective in nature. This "split scar" study directly compares two parts of the healing scar during clinic visits. Photos will be taken at each visit to track progress. Assessments will be done over a period of around 7 months using the Modified Patient and Observer Scar Assessment Scale, followed by blinded photo evaluations using the Scar Cosmesis and Rating Scale.
  • Silicone patch — DRUG
    Standard of care silicone patch will be used as the control part of the split scar study. This "split scar" study directly compares two parts of the healing scar during clinic visits. Photos will be taken at each visit to track progress. Assessments will be done over a period of around 7 months using the Modified Patient and Observer Scar Assessment Scale, followed by blinded photo evaluations using the Scar Cosmesis and Rating Scale.

Study Details

The purpose of this study is to find out what effects (good and bad) that cannabidiol (CBD) has on scar healing and appearance in patients who have undergone paramedian forehead flap reconstruction.

Key Dates

First listed
Nov 13, 2023
Start date
Sep 30, 2026
Status verified
Aug 2026
Primary completion
Jul 31, 2027
Completion
Jul 31, 2028

Study Design

Enrollment
22 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Split-scar randomized trial arm with CBD oil
    The study targets the vertical forehead scar, treating half with CBD oil and a silicone patch (experimental).
  • Placebo Comparator: Split-scar randomized trial arm without CBD oil
    The study targets the vertical forehead scar, treating the other scar half with a silicone patch (control).

Primary Outcome Measure

Assessment of subjective and objective effects of CBD on the outcomes of healing scars. [ Time Frame: 2 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Oklahoma Health Sciences CenterOklahoma CityOklahoma73104
Mark Mims, M.D., Ph.D.,
[email protected]
405-271-5504
Mark Mims, M.D., Ph.D., (PRINCIPAL_INVESTIGATOR)

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By research site
University of Oklahoma Health Sciences Center· Oklahoma City, OK