SHR-A1921 Combined With Bevacizumab in Triple-negative Breast Cancer With Brain Metastases
- Sponsor
- Fudan University
- Study ID
- NCT06210438
- Phase
- PHASE2
- Status
- Unknown
Conditions
- Brain Metastasis
- TNBC
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- SHR-A1921 + Bevacizumab — DRUGSHR-A1921 + Bevacizumab
Study Details
This is a phaseⅡ, single-arm study evaluating the efficacy and safety of SHR-A1921 Combined with Bevacizumab in Triple-negative Breast Cancer with Brain Metastases
Key Dates
- First listed
- Jan 18, 2024
- Start date
- Feb 1, 2024
- Status verified
- Dec 2023
- Primary completion
- Jun 30, 2025
- Completion
- Jun 30, 2026
Study Design
- Enrollment
- 24 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: SHR-A1921 + Bevacizumab
Primary Outcome Measure
CNS ORR [ Time Frame: from enrollment to progression or death (for any reason), assessed up to 24 months ]
Central Contacts
- Biyun Wang18017312387
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