A Study to Assess the Relative Bioavailability of 5 mg Mavacamten Opened Capsule Administered Via Nasogastric Tube Compared to Intact Oral 5 mg Mavacamten in Healthy Participants

Part of paid clinical trials in San Antonio, Texas.

Sponsor
Bristol-Myers Squibb
Study ID
NCT06211179
Phase
PHASE1
Status
Completed

Conditions

  • Healthy Volunteers

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Accepted

Interventions

Study Details

The purpose of this study to assess the relative bioavailability of 5 mg Mavacamten opened capsule administered via nasogastric tube compared to intact oral 5 mg Mavacamten in healthy volunteers.

Key Dates

Start date
Jan 10, 2024
Status verified
Sep 2024
Primary completion
Jun 13, 2024
Completion
Jun 13, 2024

Study Design

Enrollment
34 participants (actual)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Experimental: Sequence ABC
  • Experimental: Sequence BCA
  • Experimental: Sequence CAB

Primary Outcome Measure

Maximum observed concentration (Cmax) [ Time Frame: Up to 37 days ]

Locations (1)

FacilityCityStateZIPSite coordinators
Local Institution - 0001San AntonioTexas78217-

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By research site
Local Institution - 0001· San Antonio, TX

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