Stratification of Cutaneous Squamous Cell Carcinomas According to Its Transcriptomic, Metabolic and Inflammatory Characteristics

Sponsor
University Hospital, Bordeaux
Study ID
NCT06476964
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • skin biopsies — PROCEDURE
    Additional punches of 3 mm from a skin lesion part of a skin biopsy performed as part of routine care, an additional (optional) biopsy of healthy skin

Study Details

A collection of biological samples (skin) will be created to meet the objectives. Skin biopsies will be taken (excluding on face and fold), in accordance with standard practice.

Key Dates

First listed
Jun 27, 2024
Start date
Jul 4, 2024
Status verified
Jul 2024
Primary completion
Jul 31, 2026
Completion
Jul 31, 2026

Study Design

Enrollment
200 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC

Arms

  • Experimental: patients with actinic keratosis(AK)
  • Experimental: patients with squamous cell carcinoma in situ (in situ cSCC)
  • Experimental: patients with squamous cell carcinomas infiltrative (infiltrative cSCC)
  • Experimental: patient with invasive metastases (cSCC with cutaneous metastases)

Primary Outcome Measure

Relative abundance of metabolite and differential enzyme expression in tumor lesion versus healthy tissue [ Time Frame: Day 1 ]

Central Contacts

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