Fatty Acid Binding Proteins and Markers of Cellular Senescence in Cancer Survivors

Conditions

• Marker; Structural

Eligibility Criteria

Sex

ALL

Age

5 Years - 50 Years

Healthy Volunteers

Not accepted

Interventions

• Specimen #1 — OTHER
  Specimen 1 will be collected in a 10 ml SST (serum separator tube).
• Specimen #2 — OTHER
  Specimen #2 will be collected in a 10 ml SST (serum separator tube)

Study Details

The purpose of this research study is to investigate whether cancer survivors have higher levels of proteins called Fatty Acid Binding Proteins as well as 12 different markers of cellular senescence than people who have never had cancer. Investigators believe that these levels may be elevated in cancer survivors as a result of their cancer and the treatments they received and may put them at higher risk for chronic conditions such as high cholesterol, diabetes, high blood pressure, and obesity. This study will also compare the levels of these proteins and inflammatory markers in the blood with different aspects of cancer treatment the survivors received. Investigators are investigating if there is a correlation between levels of these proteins and markers, the type of treatment cancer survivors received, and development of metabolic conditions.

Key Dates

First listed

Aug 11, 2025

Start date

Jul 31, 2026

Status verified

Jun 2026

Primary completion

Dec 31, 2026

Completion

Dec 31, 2026

Study Design

Enrollment

120 participants (estimated)

Arms

• Arm: Cancer participants
• Arm: Control Group

Primary Outcome Measure

Correlation between FABP levels and the development of risk factors for metabolic syndrome and inflammation [ Time Frame: Baseline ]

Central Contacts

• Hackney Lisa, MD
  216-541-1088
  [email protected]

Locations (1)

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