Hypnosis on Breathlessness Mastery in Patients With Persistent Dyspnea

Sponsor
University Hospital, Geneva
Study ID
NCT07173348
Status
Recruiting
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Conditions

  • COPD
  • Cancer (With or Without Metastasis)
  • Chronic Heart Failure (CHF)
  • Dyspnea
  • Interstitial Lung Disease (ILD)

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Hypnosis — OTHER
    Participants will undergo three 15-minute individual hypnosis intervention, conducted by a trained hypnotherapist, with a two-week interval between each session. A guide for the session has been developed by two experimented hypnotherapists specifically for this intervention and will be used for all sessions. A total of 3 hypnosis session will be realized.

Study Details

Persistent dyspnea is a debilitating symptom, that is common and difficult to treat. This symptom is found in many different diseases including chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD), chronic heart failure (CHF), and metastatic cancer. Dyspnea is associated with many other symptoms, including anxiety, depression, and fatigue and is responsible for a significant reduction in quality of life. To date, only opiates are recommended for the pharmacological treatment of persistent dyspnea. The effectiveness of hypnosis is well known in the treatment of anxiety and delivered to patients suffering from chronic dyspnea for this reason. One randomised controlled study has shown that a single 20-minute mindfulness sessions could significantly reduce general symptom burden and have a significant impact on anxiety and depression in palliative care patients. Furthermore, the intervention had no negative side effects. Our aim is to evaluate the effectiveness of three hypnosis sessions on breathlessness mastery in patients with persistent dyspnea, using as a primary outcome the mastery domain of a validated tool, the Chronic Respiratory Questionnaire (CRQ).

Key Dates

First listed
Sep 15, 2025
Start date
Apr 1, 2026
Status verified
May 2026
Primary completion
Feb 1, 2028
Completion
Apr 1, 2028

Study Design

Enrollment
82 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE

Arms

  • Experimental: Hypnosis
    3 hypnosis sessions separated by 15 days
  • No Intervention: Usual Care
    Usual care

Primary Outcome Measure

Chronic Respiratory Questionnaire (CRQ): sub scale mastery [ Time Frame: From enrollment to the end of the intervention at 6 weeks. ]

Central Contacts

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