ACTIVATE: AI-driven Clinical-trial Trial-Information and Viability Assessment Tool for EHRs

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Dana-Farber Cancer Institute
Study ID
NCT07232043
Status
Recruiting
Apply to this trial

Conditions

  • Cancer

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • MatchMiner-AI Artificial Intelligence Tool — OTHER
    Oncologists receive email notifications containing a ranked list of potential clinical trial options when AI models detect progressive disease, in addition to standard MatchMiner-AI access.

Study Details

This study aims to develop and evaluate ACTIVATE, an AI-driven tool for clinical trial information and viability assessment using electronic health records (EHRs). The project will leverage retrospective and prospective EHR data to build and validate algorithms that identify potentially eligible participants for clinical trials and facilitate trial matching.

Key Dates

First listed
Nov 18, 2025
Start date
Jul 20, 2026
Status verified
Sep 2026
Primary completion
Jun 30, 2030
Completion
Jun 30, 2030

Study Design

Enrollment
70,000 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • No Intervention: Standard MatchMiner-AI Workflow
    Oncologists can access the MatchMiner-AI frontend website to obtain a list of clinical trial options for all participants.
  • Experimental: Proactive AI-Triggered Notifications
    Oncologists receive email notifications containing a ranked list of potential clinical trial options when AI models detect progressive disease, in addition to standard MatchMiner-AI access.

Primary Outcome Measure

Proportion clinical trials [ Time Frame: Assessment will occur at the end of the 1.5 year duration of the intervention. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Dana-Farber Cancer InstituteBostonMassachusetts02215
Kenneth Kehl, MD, MPH
[email protected]
617-632-4550
Kenneth Kehl, MD, MPH (PRINCIPAL_INVESTIGATOR)

Find similar trials in Boston, MA

By research site
Dana-Farber Cancer Institute· Boston, MA

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