geniculaR Artery eMBolization for Knee Osteoarthritis (RAMBO) Registry

Part of paid clinical trials in Libertyville, Illinois.

Sponsor
Joint & Vascular Institute
Study ID
NCT07380906
Status
Recruiting
Apply to this trial

Conditions

  • Knee Osteoarthristis

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Genicular Artery Embolization — PROCEDURE
    Genicular Artery Embolization (GAE) is a minimally invasive, image-guided procedure in which embolic agents are delivered into hyperemic genicular arteries to reduce synovial inflammation and knee pain from osteoarthritis.

Study Details

The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of genicular artery embolization (GAE) for knee osteoarthritis in adults aged 18 years or older with symptomatic KOA that has not responded to medical therapy. The main questions it aims to answer are: 1. Does GAE lead to sustained improvement in pain (WOMAC, VAS) and quality-of-life scores over 12-36 months? 2. What patient or procedural factors are associated with better outcomes after GAE? Participants will: * Undergo GAE as part of their routine clinical care. * Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires. * Have safety outcomes tracked according to Society of Interventional Radiology guidelines. There is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.

Key Dates

Start date
Jul 16, 2025
Status verified
May 2026
Primary completion
Apr 30, 2030
Completion
Jul 31, 2030

Study Design

Enrollment
1,200 participants (estimated)

Primary Outcome Measure

Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) [ Time Frame: 5 years of enrollment/patient ]

Locations (1)

FacilityCityStateZIPSite coordinators
Joint and Vascular InstituteLibertyvilleIllinois60048
Layth Alkhani
[email protected]
847-584-3959

Find similar trials in Libertyville, IL

By research site
Joint and Vascular Institute· Libertyville, IL

Related Studies