UCSF Center for Genome Surgery Biobank and Registry
Part of paid clinical trials in San Francisco, California.
- Sponsor
- University of California, San Francisco
- Study ID
- NCT07396285
- Status
- Recruiting
Conditions
- Any Conditions That Are Genetic or Suspected to be Genetic in Origin
Eligibility Criteria
- Sex
- ALL
- Age
- N/A - N/A
- Healthy Volunteers
- Accepted
Study Details
Gene editing approaches (including but not limited to: CRISPR, LNP, AAV, RNAi etc.) for the medical specialty of interventional genomics require (1) determination of the clinical relevance of genomic variants and (2) systematic evaluation of the 'editability' of those variants. Here, we seek to use in silico and in vitro analyses of genomic, cellular, and clinical data/specimens to (1) identify novel pathogenic variants underlying diseases and (2) examine the specificity and efficacy of various gene editing components across the entire human genomic landscape.
Key Dates
- First listed
- Feb 9, 2026
- Start date
- May 1, 2026
- Status verified
- Aug 2026
- Primary completion
- Dec 31, 2050
- Completion
- Dec 31, 2050
Study Design
- Enrollment
- 10,000 participants (estimated)
Arms
- Arm: Center for Genome Surgery Case Series Discussion
- Arm: Enrollment in Registry and Biobank
Primary Outcome Measure
Improve our understanding of how specific mutations lead to dysfunction and cause disease [ Time Frame: Up to 25 years ]
Central Contacts
- Emma Canepa(415) 476-7255
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| University of California, San Francisco | San Francisco | California | 94143 |
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