Relevance of the Urine Bacterial Culture Performed Before TransUrethral Resection of the Bladder for Post-operative Febrile Urinary Tract Infections Prevention: a Non-inferiority Randomized Controlled Trial

Sponsor
Poitiers University Hospital
Study ID
NCT07463963
Status
Recruiting
Apply to this trial

Conditions

  • Bladder Cancer
  • Transurethral Resection of the Bladder
  • Urinary Tract Infection Bacterial

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Urine bacterial Culture (UC) — DIAGNOSTIC_TEST
    Performing a systematic UC before the TURB surgery
  • No intervention before TURB surgery — OTHER
    No Urine Culture before TURB Surgery

Study Details

The main objective of the study is to demonstrate that not performing a systematic UC before the TURB procedure is non-inferior to performing a systematic UC in terms of the incidence of febrile UTIs during the first 30 postoperative days

Key Dates

First listed
Mar 11, 2026
Start date
Jun 29, 2026
Status verified
Aug 2026
Primary completion
Jul 29, 2030
Completion
Aug 15, 2030

Study Design

Enrollment
2,600 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: No Urine Bacterial Culture performed before TransUrethral Resection of the Bladder (TURB)
  • Active Comparator: Urine Bacterial Culture performed 4 to 10 days before TURB

Primary Outcome Measure

Proportion of patients with post-TURB symptomatic febrile Urinary Tract Infection (UTI) [ Time Frame: During the 30 days following TURB surgery. ]

Central Contacts

Find similar trials

Nationwide
Bladder cancer trialsOncology trialsUrology trials

Related Studies