Efficacy of L-menthol on Breathlessness in Asthma

Sponsor
Region Skane
Study ID
NCT07500974
Phase
PHASE2
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • L-menthol — DRUG
    (Sigma-Aldrich, St. Louis, US)
  • Placebo — OTHER
    Strawberry scent (Sigma-Aldrich, St. Louis, US)

Study Details

The purpose of this study is to assess the effect of L-menthol on breathlessness and exercise capacity in patients with Asthma.

Key Dates

First listed
Mar 30, 2026
Start date
May 31, 2026
Status verified
Feb 2026
Primary completion
Apr 30, 2027
Completion
May 31, 2027

Study Design

Enrollment
20 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: L-menthol
    In the trial, prior to performing submaximal cardio-pulmonary exercise testing (CPET), participants will be administered, L-menthol patch which will be attached to the inside of a facemask that is connected to the breathing circuit.
  • Placebo Comparator: Placebo
    For placebo, the patch will contain a similarly patch with strawberry scent.

Primary Outcome Measure

Breathlessness intensity [ Time Frame: During submaximal test, at isotime during day 2 and day 3. ]

Central Contacts

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