Morphometric Markers of the Effectiveness of Micropulse Cyclophotocoagulation

Sponsor
Kazakh Eye Research Institute
Study ID
NCT07592923
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • MicroPulse transscleral cyclophotocoagulation — PROCEDURE
    MicroPulse transscleral cyclophotocoagulation will be performed as a laser procedure for the treatment of glaucoma. Laser treatment will be applied transsclerally over the ciliary body using a power of 2500 mW. The treatment duration will be 100-120 seconds per hemifield, with 5-6 sweeps per hemifield.
  • Conventional transscleral cyclophotocoagulation — PROCEDURE
    Conventional transscleral cyclophotocoagulation will be performed as a laser procedure for the treatment of glaucoma. Laser treatment will be applied transsclerally over the ciliary body using a power of 1.4-2.3 W, with an exposure duration of 1.4-1.8 seconds per coagulation spot.

Study Details

This prospective study aims to evaluate morphometric markers of treatment response following micropulse transscleral cyclophotocoagulation (MP-CPC) in patients with glaucoma. The study will assess changes in choroidal thickness and the choroidal vascularity index (CVI) measured by optical coherence tomography (OCT) before treatment, 3-7 days after the procedure, and 1 month postoperatively. Intraocular pressure (IOP) will be measured at the same time points. The correlation between changes in choroidal thickness, the choroidal vascularity index (CVI) and IOP reduction will be analyzed. Additionally, the study seeks to determine the minimal baseline choroidal thickness associated with a clinically significant hypotensive effect after MP-CPC.

Key Dates

First listed
May 18, 2026
Start date
May 18, 2026
Status verified
May 2026
Primary completion
Aug 18, 2026
Completion
Aug 18, 2026

Study Design

Enrollment
20 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: MicroPulse transscleral cyclophotocoagulation group
    Participants in this group will undergo MicroPulse transscleral cyclophotocoagulation for glaucoma. The procedure will be performed using a laser power of 2500 mW, with a treatment duration of 100-120 seconds per hemifield and 5-6 sweeps per hemifield.
  • Experimental: Conventional transscleral cyclophotocoagulation group
    Participants in this group will undergo conventional transscleral cyclophotocoagulation for glaucoma. The procedure will be performed using a laser power of 1.4-2.3 W, with an exposure duration of 1.4-1.8 seconds per coagulation spot.

Primary Outcome Measure

Changes in intraocular pressure measurements between baseline and postoperative follow-up visits [ Time Frame: Day 1, Day 3, Week 1, Week 2, Month 1 ]

Central Contacts

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