Glaucoma Clinical Trials

Recruiting glaucoma studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat glaucoma. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting glaucoma studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting glaucoma trials

Within

Know Your Pressures NYC

for Glaucoma

1 site in New York

Sponsor: Columbia University

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT05992415

The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients

for Glaucoma

1 site in New Orleans

Sponsor: Tulane University

Sex: All·Age: 18+

Code: NCT04007276·Phase 4

Impact of Meditation on Reducing Stress in Glaucoma Patients: An Electronic Feasibility Study

for Glaucoma

Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Sex: All·Age: 65+

Code: NCT07769463

Glaucoma Drop Aids Part 2

for Glaucoma

1 site in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 18+

Code: NCT06806332

Baerveldt Versus Paul Study

for Glaucoma

Sponsor: University of Sydney

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07733453·Phase 4

Effect of Late Ripcord Removal From Glaucoma Drainage Device

for GLAUCOMA 1, OPEN ANGLE, D (Disorder)

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT07803536

Optimizing Graft Selection in Glaucoma Surgery: A Comparative Study of Sclera, Pericardium, and Corneal Tissue

for Glaucoma

Sponsor: University of Alberta

Sex: All·Age: 18 - 110

Code: NCT07285616

The iD2: A Smart Eye Drop Cap Monitor for Eye Drop Adherence

for Glaucoma

Sponsor: Universal Adherence LLC

Sex: All·Age: 18+

Code: NCT07664943

Blinking Exercise Study

for Dry Eye Disease (DED)

Sponsor: St. Joseph's Healthcare Hamilton

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07554937

A Study About the Safety of ASP2767 and Whether it Helps People With Glaucoma-Related Optic Nerve Damage

for Glaucoma

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07770685·Phase 1, Phase 2

Magnetic Resonance Imaging of Cerebral Connectivity and Volume in Neurodegeneration and Glaucoma

for Glaucoma

Sponsor: University Hospital, Bordeaux

Sex: All·Age: 18+

Code: NCT07802769

Apply to this trial

VividFlo System Validation Study

for Glaucoma

Sponsor: VividWhite Pty Ltd

Sex: All·Age: 18+

Code: NCT07754201

The Effectiveness Of Home-Based Circuit Training On Eye Pressure And Eye Nerve Structures In Patients With Glaucoma

for Glaucoma

Sponsor: Universiti Sains Malaysia

Sex: All·Age: 18 - 70

Code: NCT07733388

Innovative Tube Trabeculectomy for Advanced and Refractory Glaucoma: A Randomized Controlled Trial

for Glaucoma

Sponsor: Benha University

Sex: All·Age: 18+

Code: NCT07755761

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Evaluation of the Safety, Efficacy, Dose Response of the Bimatoprost Drug Ring System (BIM-DRS) in Pseudophakic Patients Diagnosed With Open Angle Glaucoma or Ocular Hypertension

for Glaucoma

Sponsor: SpyGlass Pharma, Inc.

Sex: All·Age: 22+

Code: NCT07641296·Phase 1

Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment

for Retinitis Pigmentosa (RP)

Sponsor: University of Waterloo

Sex: All·Age: 18+

Code: NCT07341763

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Cross-modal Neuromodulation to Improve Balance and Cognition in Older Adults With Glaucoma: A Randomized Trial of Cerebellar Transcranial Electrical Stimulation

for Glaucoma

Sponsor: The Hong Kong Polytechnic University

Sex: All·Age: 55+

Code: NCT07771699

Apply to this trial

GlaukomAI: Clinical Validation of an AI System for Early Glaucoma Screening

for Glaucoma

Sponsor: Fondazione G.B. Bietti, IRCCS

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07668193

Optic Nerve Head Strain in Non-glaucoma Subjects

for Glaucoma

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 30 - 90·Accepts healthy volunteers

Code: NCT07425535·EARLY_Phase 1

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Imaging the Effects of Netarsudil (Rhopressa) on the Trabecular Meshwork in Glaucoma and Ocular Hypertension

for Glaucoma

1 site in Bloomington

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT07588152·Phase 4

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Retinal Ganglion Cell Neuroprotection Under Prostaglandin Analogues

for Glaucoma

Sponsor: Association for Innovation and Biomedical Research on Light and Image

Sex: All·Age: 18+

Code: NCT07074782

Rocklatan vs Latanoprost Post-DSLT

for Glaucoma

1 site in Beaumont

Sponsor: Eye Centers of Southeast Texas

Sex: All·Age: 18+

Code: NCT07465913·Phase 4

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Artificial Intelligence-assisted Diagnosis in Ophthalmology

for Macular Degeneration

Sponsor: Marisse Masis-Solano

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07497815

Efficacy and Safety of a Releasable Intraluminal Suture Technique to Reduce Hypotony Following Glaucoma Surgery Using the Preserflo Device

for Glaucoma

Sponsor: Hôpital Privé de la Baie

Sex: All·Age: 18+

Code: NCT07531199

Impact of a Glaucoma Awareness Program on Treatment Adherence

for Glaucoma

Sponsor: Seva Canada Society

Sex: All·Age: 18+

Code: NCT07488234

World Sight Foundation Field Machine (WSFFM) Pilot

for Glaucoma

Sponsor: Buckinghamshire Healthcare NHS Trust

Sex: All·Age: 18 - 99

Code: NCT07674069

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Validation of the Artificial Intelligence Subsystem of the DDART Medical Device for the Automated Detection of Lesions Compatible With Glaucoma in a Random Sample of Retinal Fundus Photographs

for Glaucoma

Sponsor: Democritus University of Thrace

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07758569

Apply to this trial

Change in IOP Fluctuation After DSLT

for Glaucoma

1 site in Fort Worth

Sponsor: Ophthalmology Associates, Fort Worth

Sex: All·Age: 18+

Code: NCT07428668

Apply to this trial

Modified Trabeculectomy After Failure of Combined Phaco With GATT

for Glaucoma

Sponsor: Assiut University

Sex: All·Age: 21 - 70

Code: NCT07455786

Apply to this trial

Advancing Pediatric Retinal Imaging With Auto-aligned OCT

for Eye Diseases

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 1 Month+·Accepts healthy volunteers

Code: NCT06841575

Apply to this trial

Automated Applanation Tonometry - Updated

for Glaucoma

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT07298356

Apply to this trial

This Study Examines Whether Personality Traits Influence the Frequency or Severity of Ocular Adverse Effects Reported by Patients Using Glaucoma Medications. The Findings May Identify Patients at Greater Risk of Intolerance and Support More Personalized Treatment and Counselling.

for Glaucoma

Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre

Sex: All·Age: 18+

Code: NCT07739784

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Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant

for Glaucoma

1 site in Dothan

Sponsor: Glaukos Corporation

Sex: All·Age: 18+

Code: NCT07495852·Phase 3

Apply to this trial

Glaucoma Screening to Enhance At-Risk Californians' Health

for Glaucoma

2 sites incl. Oakland

Sponsor: University of California, San Francisco

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT06854198

Apply to this trial

Efficacy of Biofeedback Training for Glaucoma

for Glaucoma

Sponsor: University Health Network, Toronto

Sex: All·Age: All ages

Code: NCT07409077

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Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

for Glaucoma

1 site in Miami

Sponsor: University of Miami

Sex: All·Age: 18+

Code: NCT07217678·Phase 4

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Strategies for Improving Linkage-to-Care After Eye Disease Screening

for Age Related Macular Degeneration

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 60+

Code: NCT06943599

Apply to this trial

Rocklatan Retinal Perfusion OCT Study

for Glaucoma

1 site in Portland

Sponsor: Oregon Health and Science University

Sex: All·Age: 21+

Code: NCT07174401·Phase 4

Effectiveness of a Large Language Model-Based Educational Tool on Visual Field Test Reliability in Glaucoma Patients

for Glaucoma

1 site in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT07327242

Repetitive Transcranial Alternating Current Stimulation (rtACS) for the Treatment of Optic Neuropathies

for Glaucoma

Sponsor: National Taiwan University Hospital

Sex: All·Age: 18+

Code: NCT07145073

Apply to this trial

DSLT in Normal Tension Glaucoma (NTG) Asian Eyes

for Normal Tension Glaucoma (NTG)

1 site in San Jose

Sponsor: Ngoc Nguyen Inc.

Sex: All·Age: 20+

Code: NCT07300852

Michigan Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (SIGHT) 2

for Eye Diseases

1 site in Flint

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06934577

Apply to this trial

Long-Term Clinical Results of Ab-Interno Trabeculotomy in Glaucoma Management

for Glaucoma

Sponsor: Wuerzburg University Hospital

Sex: All·Age: 18+

Code: NCT07780916

Apply to this trial

Safety and Effectiveness of PreserFlo and XEN Stents With or Without Amniotic Membrane in Glaucoma Surgery

for Glaucoma

Sponsor: Nova Scotia Health Authority

Sex: All·Age: 18+

Code: NCT07143708

High-throughput Large-model-based AI-assisted Diagnosis Using OCT

for Diabetic Retinopathy (DR)

Sponsor: Peking Union Medical College Hospital

Sex: All·Age: All ages

Code: NCT07249307

Glaucoma Screening Using Artificial Intelligence Assisted Clinical Model in Singapore's Diabetic Eye Screening Program

for Glaucoma

Sponsor: Singapore Eye Research Institute

Sex: All·Age: 21+

Code: NCT07243665

Apply to this trial

Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma

for Glaucoma

1 site in Kansas City

Sponsor: Insight Eyecare Specialties, Inc. dba Vision Source Eyecare,

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07209410·Phase 4

Apply to this trial

Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)

for Cataract

1 site in San Antonio

Sponsor: SpyGlass Pharma, Inc.

Sex: All·Age: 22+

Code: NCT07218796·Phase 3

Apply to this trial

Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers

for Glaucoma

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT06629649

Apply to this trial

Smart Soft Contact Lenses for Monitoring Glaucoma

for Glaucoma

1 site in Bloomington

Sponsor: Indiana University

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT07224542

Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)

for Cataract

1 site in Houston

Sponsor: SpyGlass Pharma, Inc.

Sex: All·Age: 22+

Code: NCT07218783·Phase 3

Apply to this trial

Efficacy and Safety of iStent in Reducing Intraocular Pressure in Open-angle Glaucoma

for Glaucoma

Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT07354009

Apply to this trial

Intraocular Pressure Measured by a Novel Sensing Contact Lens Versus Tonometry

for Glaucoma

Sponsor: Sensimed AG

Sex: All·Age: 18+

Code: NCT04024293

Apply to this trial

Nicotinamide Levels in Serum, Aqueous Humor, and Tear Film in Glaucoma and Correlations With Mitochondrial Damage-Associated Molecular Patterns (mtDAMPs) and Senescence-Associated Secretory Phenotype (SASP)

for Glaucoma

Sponsor: Università degli Studi 'G. d'Annunzio' Chieti e Pescara

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07006194

A Study Evaluating the Safety and Efficacy of MINIject S+ in Subjects With Open Angle Glaucoma

for Glaucoma

Sponsor: iSTAR Medical

Sex: All·Age: 20+

Code: NCT07009236

Apply to this trial

Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma Progression

for Glaucoma

Sponsor: The University of Hong Kong

Sex: All·Age: 18+

Code: NCT05940623

Apply to this trial

Altered Non-Visual Photoreception in Patients With Glaucoma: Impacts on Sleep, Alertness, Mood, and Cognition

for Glaucoma

Sponsor: National University of Singapore

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT07364929

Apply to this trial

Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy

for Glaucoma

1 site in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06993597

Apply to this trial

Multi-modal Intelligent Diagnosis System for Multiple Ophthalmic Diseases

for Retina Disease

Sponsor: Beijing Hospital

Sex: All·Age: 20 - 90

Code: NCT07143851

To Study Ocular Outflow Dynamics of the Eye Using Intraoperative Tonographic Biometry and Assess Its Predictive Value in Improving Postoperative Outcomes.

for Cataract

1 site in New York

Sponsor: The New York Eye & Ear Infirmary

Sex: All·Age: 18+

Code: NCT07425496

Apply to this trial

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Glaucoma clinical trials — common questions

Are glaucoma clinical trials free to join?

Yes. Participating in a glaucoma clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a glaucoma clinical trial?

Each glaucoma study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a glaucoma trial near me?

Use the location controls above. We'll show recruiting glaucoma trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many glaucoma trials are recruiting right now?

We're currently tracking roughly 54 recruiting glaucoma trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Glaucoma trials by city

Palo Alto, CA San Francisco, CA Boston, MA Bloomington, IN Anaheim, CA Ann Arbor, MI Birmingham, AL Cincinnati, OH Flint, MI Fountain Valley, CA Grand Junction, CO Miami, FL

Related specialties

Ophthalmology