The Effect of Osteopathic Manipulative Techniques on Human Tear Proteins

Part of paid clinical trials in Erie, Pennsylvania.

Sponsor
Lake Erie College of Osteopathic Medicine
Study ID
NCT07633496
Status
Not Yet Recruiting

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Conditions

  • No Disease or Condition is Being Directly Studied
  • The Focus of the Study in Healthy Volunteers

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Osteopathic Manipulative Treatment — OTHER
    Sequential OMT of suboccipital 4-step release, occipital mastoid suture release, and sphenopalatine ganglion release.
  • Sham — OTHER
    Sham protocol including holding of the occiput and thoracic area and cranial vault hold without interaction with the motion.

Study Details

This is a pilot study to determine if osteopathic manipulation can alter the concentration of proteins in human tears.

Key Dates

Start date
Jul 31, 2026
Status verified
Jun 2026
Primary completion
Aug 31, 2026
Completion
Oct 31, 2026

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Osteopathic Manipulative Treatment
    Sequential OMT of suboccipital 4-step release, occipital mastoid suture release, and sphenopalatine ganglion release.
  • Sham Comparator: Sham

Primary Outcome Measure

Total tear protein concentration [ Time Frame: Baseline, 1 hour, and 1 week ]

Central Contacts

Locations (1)

FacilityCityStateZIP
Plaza 38 Medical OfficesEriePennsylvania16506

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Plaza 38 Medical Offices· Erie, PA