Phase 2 Trial of G207 + 5 Gy Radiation for Children With High-Grade Gliomas

Part of paid clinical trials in Houston, Texas.

Sponsor
M.D. Anderson Cancer Center
Study ID
NCT07649070
Phase
PHASE2
Status
Not Yet Recruiting

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Conditions

  • High Grade Gliomas

Eligibility Criteria

Sex
ALL
Age
3 Years - 21 Years
Healthy Volunteers
Not accepted

Interventions

  • G207 — DRUG
    Given by injection

Study Details

The goal of this clinical research study is to learn about the safety and effects of G207 combined with radiation therapy in patients with recurrent or progressive high-grade glioma (HGG).

Key Dates

Start date
Nov 30, 2026
Status verified
Jun 2026
Primary completion
Dec 31, 2030
Completion
Dec 31, 2032

Study Design

Enrollment
38 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Treatment with G207 (IT) + 5 Gy Radiation
    Treatment will be administered on a inpatient basis.

Primary Outcome Measure

Safety and Adverse Events (AEs) [ Time Frame: Through study completion; an average of 1 year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UT MD AndersonHoustonTexas77030
Gregory Friedman, MD
713-557-4400
Gregory Friedman, MD (PRINCIPAL_INVESTIGATOR)

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