The Efficacy of Vitamin D Supplementation to Sustain Performance Outcomes

Part of paid clinical trials in Silver Spring, Maryland.

Sponsor
Walter Reed Army Institute of Research (WRAIR)
Study ID
NCT07654777
Status
Recruiting
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Conditions

  • Acute Stress Reaction

Eligibility Criteria

Sex
ALL
Age
18 Years - 40 Years
Healthy Volunteers
Accepted

Interventions

  • Vitamin D3 (Cholecalciferol) — DIETARY_SUPPLEMENT
    4,000 IU daily oral administration for 8 weeks.
  • Oral Placebo Tablet — DIETARY_SUPPLEMENT
    Daily administration of two oral placebo tablets for 8 weeks

Study Details

The goal of this clinical trial is to find out if vitamin D supplements help healthy adults maintain their cognitive and simple physical task performance and emotional state during highly stressful situations. The main question it aims to answer is: \- Does vitamin D help maintain cognitive and physical task performance and emotional state during highly stressful situations? Researchers will compare vitamin D to placebo (a look-alike tablet that contains no active ingredients) to see if vitamin D better maintain cognitive and physical task performance and emotional state during highly stressful situations. Participants will: * Take vitamin D or placebo tablets daily for 8 weeks. * Perform cognitive and simple physical tasks and rate their emotional state under highly stressful situations. * Wear a stress belt that delivers mild electric shocks 1 - 5 times while participants are performing laboratory tasks. * Wear a wristwatch-shaped activity monitor for 9 weeks. * Visit the laboratory 5 times.

Key Dates

Start date
Jun 30, 2026
Status verified
Jun 2026
Primary completion
Sep 30, 2027
Completion
Sep 30, 2027

Study Design

Enrollment
52 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: Vitamin D3
    Daily self-administration of two 2,000 International Unit (IU) vitamin D3 tablets for 8 weeks.
  • Placebo Comparator: Placebo
    Daily self-administration of two placebo tablets for 8 weeks.

Primary Outcome Measure

Percentage correct for No-Go trials in the Go/No-Go task [ Time Frame: From baseline to the end of study product supplementation at 9 weeks. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Sleep Research Center (SRC), Walter Reed Army Institute of Research (WRAIR)Silver SpringMaryland20910
Lonique Moore, MSPH
[email protected]
301-319-9287
Beza Negash, BS, BA
[email protected]
301-319-9287

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By research site
Sleep Research Center (SRC), Walter Reed Army Institute of Research (WRAIR)· Silver Spring, MD

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