As of August 2026, 58 paid clinical trials are recruiting in Silver Spring, Maryland. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Silver Spring offers studies at sites including Holy Cross Hospital for conditions such as Breast Cancer, Endometrial Cancer, Acute Stress Reaction, Carcinoma, Non-Small-Cell Lung. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Researchers run research studies in Silver Spring, MD at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Holy Cross Hospital | Carcinoma, Ovarian Epithelial, Endometrial Cancer, Endometrioid Ovarian Cancer | 8 |
| Maryland Oncology Hematology, P.A. | Gastroesophageal Junction Cancer, Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung | 5 |
| Adventist Healthcare White Oak Medical Center | Interstitial Lung Disease, Progressive Pulmonary Fibrosis, Acute Myocardial Infarction | 3 |
| Maryland Oncology Hematology | Cancer, Chronic Lymphocytic Leukemia (CLL), Metastatic Prostate Cancer | 3 |
| Maryland Oncology Hematology - Silver Spring | Untreated, Unresectable, or Metastatic Colorectal Cancer, Chronic Lymphocytic Leukemia, Multiple Myeloma | 3 |
| Food and Drug Administration | Age-Related Macular Degeneration, Cone Dystrophy, Cone Rod Dystrophy | 2 |
| Jadestone Clinical Research | COVID-19 Infection, COVID-19 SARS-CoV-2 Infection | 2 |
| Maryland Oncology Hematology P A | Carcinoma, Non-Small-Cell Lung, Early Breast Cancer | 2 |
| TSC Alliance | Adult Caregivers of Individuals With TSC, Lymphangioleiomyomatosis, Tuberous Sclerosis | 2 |
| Holy Cross Hospital - Silver Spring | Breast Cancer, Folate Receptor-Alpha Positive, Recurrent Ovarian Cancer | 2 |
| ACCOMPLISH-1 Research Site | Chronic Weight Management, Obesity, Overweight | 1 |
| ACCOMPLISH-2 Research Site | Chronic Weight Management, Obesity, Overweight | 1 |
| Children's National Medical Center, Children's Research Institute | Caregiver Burden, Tracheostomy | 1 |
| Childrens National Hospital | Palliative Care Education | 1 |
| Direct Biologics Investigational Site | ARDS, Acute Respiratory Distress Syndrome | 1 |
| Food and Drug Administration (FDA) | Glaucoma | 1 |
| Jadestone Clinical Research, LLC | Percutaneous Coronary Intervention, Peripheral Endovascular Intervention | 1 |
| Javara | Focal Epilepsy | 1 |
| Javara Inc./Privia Medical Group - Silver Spring, MD - Columbia Pike | Proteinuric Kidney Disease | 1 |
| Local Institution - 0523 | Non-Small Cell Lung Cancer | 1 |
| Maryland Eye Consultants and Surgeons | Ocular Hypertension, Suspect Glaucoma | 1 |
| Maryland Oncology Hematology P.A. | Breast Cancer | 1 |
| Maryland Oncology Hematology, PA | Breast Cancer | 1 |
| Massive Bio SYNERGY-AI site | BRCA Gene Rearrangement, Bladder Cancer, Breast Cancer | 1 |
| Medical Center Orthotics and Prosthetics - Silver Spring | Upper Limb Amputation Above Elbow, Upper Limb Amputation Below Elbow | 1 |
Recruiting trials in Silver Spring grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 58 recruiting clinical trials in Silver Spring, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Silver Spring compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Silver Spring include Breast Cancer (4), Endometrial Cancer (4), Acute Stress Reaction (2), Cancer (2), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Silver Spring on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Silver Spring include Holy Cross Hospital, Maryland Oncology Hematology, P.A., Adventist Healthcare White Oak Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Silver Spring are Cancer & tumors (29), Eye & vision (4), Vaccines (3). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.