Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 4

Part of paid clinical trials in Boulder, Colorado.

Sponsor
L. Cinnamon Bidwell
Study ID
NCT07679581
Status
Recruiting
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Conditions

  • Cannabis
  • Electroencephalography
  • Memory

Eligibility Criteria

Sex
ALL
Age
21 Years - 40 Years
Healthy Volunteers
Accepted

Interventions

  • Cannabis (smoked flower) — DRUG
    Self directed use (ad libitum)

Study Details

This study investigates the impact of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on recognition memory in healthy, regular cannabis users. Participants complete the same recognition memory task after self-administering one of two different strains of cannabis flower one day and while not intoxicated another day. Event-related potentials (ERPs) are measured via electroencephalogram (EEG) during the recognition memory task. Blood is collected to quantify THC and CBD exposure. Participants also complete self-report measures of medical history, sleep quality, subjective cognitive function, physical activity, psychological functioning, substance use, and acute drug effects.

Key Dates

Start date
Dec 10, 2025
Status verified
Jun 2026
Primary completion
Feb 1, 2027
Completion
May 31, 2027

Study Design

Enrollment
64 participants (estimated)

Primary Outcome Measure

Difference in ERP amplitude (FN400) [ Time Frame: Intoxicated session and not-intoxicated session (about 1 week) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Center for Innovation and Creativity (CINC)BoulderColorado80301
Katie N Paulich, Ph.D.
[email protected]
303-492-9549
Timothy Curran, Ph.D. (PRINCIPAL_INVESTIGATOR)

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By research site
Center for Innovation and Creativity (CINC)· Boulder, CO

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