The Abuse Liability of IQOS Heated Tobacco Products Among Adults Who Smoke

Part of paid clinical trials in Columbus, Ohio.

Sponsor
Ohio State University Comprehensive Cancer Center
Study ID
NCT07688304
Status
Recruiting
Apply to this trial

Conditions

  • Tobacco

Eligibility Criteria

Sex
ALL
Age
21 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • Smoking Behavioral Research (IQOS) — BEHAVIORAL
    Use IQOS HeatSticks (flavor matched to the participant's usual cigarette)
  • Smoking Behavioral Research (UBC) — BEHAVIORAL
    Smoke UBC

Study Details

This clinical trial aims to evaluate user sensory experiences and smoking behavior when using IQOS heated tobacco products (HTPs) among adults who smoke cigarettes.

Key Dates

First listed
Jul 7, 2026
Start date
Aug 27, 2026
Status verified
Aug 2026
Primary completion
Jul 31, 2027
Completion
Oct 31, 2027

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER

Arms

  • Other: Arm I (IQOS HeatSticks, Usual Brand Cigarette [UBC])
    Participants use IQOS HeatSticks (flavor matched to their usual cigarette) ad lib over 60 minutes during laboratory visit 1. At least forty-eight hours later, participants smoke their UBC ad lib over 60 minutes during laboratory visit 2.
  • Other: Arm II (UBC, IQOS HeatSticks)
    Participants smoke their UBC ad lib over 60 minutes during laboratory visit 1. At least forty-eight hours later, participants use IQOS HeatSticks (flavor matched to their usual cigarette) ad lib over 60 minutes during laboratory visit 2.

Primary Outcome Measure

Product Appeal [ Time Frame: Minute 5 of product use session, Minute 35 of product use session, Minute 60 of product use session ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Ohio State University Comprehensive Cancer CenterColumbusOhio43210
Alayna P. Tackett, PhD
[email protected]
844-744-2447
Alayna P. Tackett, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
Ohio State University Comprehensive Cancer Center· Columbus, OH

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