Paid Clinical Trials in Columbus, OH
As of July 2026, 1,360 paid clinical trials are recruiting in Columbus, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Columbus offers studies at sites including Ohio State University Comprehensive Cancer Center for conditions such as Acute Myeloid Leukemia, Breast Cancer, Ovarian Cancer, Chronic Lymphocytic Leukemia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Columbus
Trials by drug in Columbus
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Newly added in Columbus
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Self-Supervised Constraint-Induced Movement Therapy for Stroke Recovery
Evaluating Whether a Nausea Band Reduces Symptoms in Those With Chronic Nausea Vomiting
AROMA-NT: Essential Oils and Wearable TENS Device for Chronic Nausea
Using the CompuFlo® CathCheck™ System to Check Epidural Catheter Function Before Tubal Ligation: A Pilot Study
Virtual Poetry Workshops to Enhance Patient Well Being and Reduce Anxiety
1,206 clinical trials
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
A Study of Brenipatide in Participants With Opioid Use Disorder
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
Parasternal Extravascular ICD System Pivotal Clinical Investigation (ALARION EV) Study
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder
A Study of Buntanetap in Participants With PD
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
Top Research Study Locations in Columbus
Researchers run research studies in Columbus, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Ohio State University Comprehensive Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 244 |
| Nationwide Children's Hospital | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Surgery | 217 |
| The Ohio State University | Heart Failure, Treatment Resistant Depression, Alzheimer's Disease | 136 |
| Ohio State University | Colorectal Cancer, Coronary Artery Disease, NSCLC | 126 |
| The Ohio State University Wexner Medical Center | Follicular Lymphoma, Endometrial Cancer, Hypertension | 75 |
| Riverside Methodist Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 30 |
| Ohio State University Wexner Medical Center | Anxiety, Chronic Nausea, Endometrial Cancer | 26 |
| Doctors Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 24 |
| Grant Medical Center | Anatomic Stage IV Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 24 |
| The Mark H Zangmeister Center | Malignant Solid Neoplasm, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 24 |
| Mount Carmel East Hospital | Malignant Solid Neoplasm, Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer | 22 |
| The Ohio State University Comprehensive Cancer Center | Cancer, Colorectal Cancer, CRC | 22 |
| Columbus Oncology and Hematology Associates Inc | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 17 |
| Mount Carmel Health Center West | Malignant Solid Neoplasm, Acral Lentiginous Melanoma, Acute Lymphoblastic Leukemia | 17 |
| Ohio State University Medical Center | AL Amyloidosis, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 16 |
| OhioHealth Research Institute | Atrial Fibrillation, Acute Ischemic Stroke, Acute Myeloid Leukaemia (AML) | 13 |
| OSU Wexner Medical Center | Intracerebral Hemorrhage, Ischemic Stroke, Acute Hypoxic Respiratory Failure | 12 |
| The Ohio State University Medical Center | AADC Deficiency, Abdominal Aortic Aneurysm, Bone Marrow Transplant (BMT) | 11 |
| The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine | Pregnancy, High Risk, Preeclampsia, Gestational Hypertension | 10 |
| Clinical Trial Site | AQP4+ NMOSD, ATTR Amyloidosis, Breast Cancer | 9 |
| Ohio Health Research Institute | Aortic Dissection, Aortic Valve Disease, Aortic Valve Stenosis | 9 |
| Ohio State University Hospital | Acute Decompensated Heart Failure, Advanced Solid Tumor, Fracture Fixation | 8 |
| OhioHealth Riverside Methodist Hospital | Aortic Stenosis, Carcinoma, Non-Small-Cell Lung, Coronary Artery Disease | 8 |
| GSK Investigational Site | Gastrointestinal Neoplasms, Hypereosinophilic Syndrome, Irritable Bowel Syndrome | 7 |
| Nationwide Children's Hosptial | Primary Immune Deficiency Disorder, Adenovirus, Congenital Cytomegaloviral (CMV) Disease | 7 |
Active & Upcoming Studies in Columbus (2026)
Recruiting trials in Columbus grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (490 active studies)
- Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma · Phase 1 · Northwestern University
- Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital · Ohio State University Comprehensive Cancer Center
Cardiovascular (76 active studies)
- Health Coaching for Patients With Cardiovascular Disease · Ohio State University
- Evaluating the Effects of a Mindfulness Intervention on Health Outcomes in Individuals With Hypertension · Ohio State University
Neurology & pain (66 active studies)
- Prescriptive Infusion Algorithm (PIA) · Phase 2 · AskBio Inc
- A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple Sclerosis Who Switch From an Approved Anti-CD20 Therapy · Phase 4 · Genentech, Inc.
Mental health & behavior (49 active studies)
- A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety · Phase 2 · Ohio State University
- Studying the Impacts of Higher Taxes and Bans on Electronic Cigarettes to Improve Public Health · Ohio State University Comprehensive Cancer Center
Diabetes & metabolic (38 active studies)
- Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Pediatric (35 active studies)
- VR-PAT and fNIRS to Identify CNS Biomarkers of Pain · Nationwide Children's Hospital
- Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). · Phase 2 · BrainChild Bio, Inc
HIV / STI (12 active studies)
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
Vaccines (7 active studies)
- A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease · Phase 3 · Pfizer
- REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19 · Duke University
Eye & vision (7 active studies)
- Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) · Phase 3 · AbbVie
- A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK · Phase 3 · Kodiak Sciences Inc
Common conditions studied in Columbus
- Acute Myeloid Leukemia (20 active studies)
- Breast Cancer (20 active studies)
- Ovarian Cancer (18 active studies)
- Chronic Lymphocytic Leukemia (17 active studies)
- Endometrial Cancer (16 active studies)
- Stage IV Lung Cancer AJCC v8 (15 active studies)
Leading research sponsors in Columbus
- Ohio State University
- Ohio State University Comprehensive Cancer Center
- National Cancer Institute (NCI)
- Nationwide Children's Hospital
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Columbus?
There are approximately 1,360 recruiting clinical trials in Columbus, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Columbus pay participants?
Most recruiting trials in Columbus compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Columbus?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Columbus?
The most common conditions under active study in Columbus include Acute Myeloid Leukemia (20), Breast Cancer (20), Ovarian Cancer (18), Chronic Lymphocytic Leukemia (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Columbus?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Columbus on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Columbus?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Columbus?
Recruiting research sites in Columbus include Ohio State University Comprehensive Cancer Center, Nationwide Children's Hospital, The Ohio State University, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Columbus right now?
The largest active categories in Columbus are Cancer & tumors (490), Cardiovascular (76), Neurology & pain (66). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.