UPRIGHT-PRO: Prospective Development Study of Upright Proton Therapy

Conditions

• Proton Therapy

Eligibility Criteria

Sex

ALL

Age

N/A - N/A

Healthy Volunteers

Not accepted

Interventions

• Standard-of-Care Proton Therapy — RADIATION
  Participants receive standard-of-care proton therapy at Stanford. Treatment is not assigned by the study.

Study Details

This study is being done to evaluate whether cancer patients can safely and reliably receive proton radiation therapy while positioned upright. Proton therapy is an established form of radiation treatment, and the upright treatment system used in this study has been cleared by the U.S. Food and Drug Administration. The intent of this protocol is to observe the treatment methods, doses, and outcomes for the initial cohorts of patients treated with this upright device. This study will support research activities and evaluate feasibility as needed. Results of this study will be reported in the scientific literature but the investigators do not intend to report to the FDA for a new use or indication or change to the labeling; nor are the investigators required to do so.

Key Dates

First listed

Jul 16, 2026

Start date

Sep 30, 2026

Status verified

Jul 2026

Primary completion

Sep 30, 2027

Completion

Sep 30, 2027

Study Design

Enrollment

450 participants (estimated)

Arms

• Arm: Participants Receiving Standard-of-Care Proton Therapy
  Participants with cancer receiving standard-of-care proton therapy at Stanford.

Primary Outcome Measure

Feasibility of upright proton therapy [ Time Frame: End of proton therapy (3 months) ]

Central Contacts

• Aryan Dwivedi
  [email protected]
  [email protected]

Locations (2)

Find similar trials in Palo Alto, CA