Protoacoustic Imaging For 3D Mapping

Part of paid clinical trials in Oklahoma City, Oklahoma.

Sponsor: University of Oklahoma
Study ID: NCT07832617
Status: Recruiting

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Conditions

Liver Cancer
Prostate Cancer
Proton Therapy
Radiation Therapy, Secondary Skin Reactions

Eligibility Criteria

Sex: ALL
Age: 18 Years - N/A
Healthy Volunteers: Not accepted

Interventions

Radiacoustic Imaging w/Ultrasound. — DEVICE
A robotic arm will position the ultrasound matrix array on the lower abdomen.

Study Details

The purpose of this study is to test a new imaging technology called radioacoustic imaging (RAI) that may help doctors see where radiation is being delivered during proton therapy. During proton therapy, the radiation treatment produces very small sound signals inside the body. This study will use special ultrasound sensors placed on the outside of the body to detect these signals. The information collected may allow researchers to create a picture showing where the radiation dose is being delivered in the body and how much radiation is reaching the treatment area. The goal is to determine whether this technology can safely and accurately measure radiation during proton therapy without requiring any additional procedures or radiation exposure.

Key Dates

First listed: Sep 22, 2026
Start date: Jun 10, 2026
Status verified: Sep 2026
Primary completion: Jun 30, 2028
Completion: Jun 30, 2030

Study Design

Enrollment: 24 participants (estimated)

Arms

Arm: Proton Therapy In Vivo
This prospective clinical trial will evaluate the use of RAI in 24 cancer patients, including 12 patients with liver cancer and 12 patients with prostate cancer, using a noninvasive device. The device consists of a small ultrasound transducer placed on the participant's body that delivers low-intensity sound signals through the body to evaluate the treatment.