PROSPECT Registry for Individuals at Risk for Genetic Prion Disease

Part of paid clinical trials in Cleveland, Ohio.

Sponsor
Brian Appleby
Study ID
NCT07732608
Status
Recruiting
Apply to this trial

Conditions

  • Prion Diseases

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Study Details

PROSPECT is a prospective observational registry and longitudinal natural history study of adults at risk for genetic prion disease.

Key Dates

First listed
Jul 29, 2026
Start date
Aug 25, 2026
Status verified
Aug 2026
Primary completion
Aug 31, 2036
Completion
Aug 31, 2036

Study Design

Enrollment
2,000 participants (estimated)

Arms

  • Arm: Individuals at risk for Genetic Prion Disease
    Adults age 18 years and older who are at risk for genetic prion disease based on family history and enrolled in the PROSPECT longitudinal natural history registry.

Primary Outcome Measure

Disease Onset or Death [ Time Frame: Baseline and annual follow-up assessments for up to 10 years after enrollment. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University Hospitals Cleveland Medical CenterClevelandOhio44106
Margaret Verba, MA
[email protected]
216-368-2062

Find similar trials in Cleveland, OH

By research site
University Hospitals Cleveland Medical Center· Cleveland, OH

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