A Study to Learn About the Study Medicine Called Tilrekimig in People With Severe Asthma

Part of paid clinical trials in Garland, Texas.

Sponsor
Pfizer
Study ID
NCT07772921
Phase
PHASE3
Status
Not Yet Recruiting

Notify me when recruiting opens

Save your spot on the interest list for this study. We'll keep your details with this study so our team can follow up when recruiting opens.

Not yet recruiting

Add your contact details and location so we can keep your interest tied to this study.

Conditions

Eligibility Criteria

Sex
ALL
Age
12 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • tilrekimig — DRUG
    subcutaneous injection
  • Placebo — OTHER
    subcutaneous injection

Study Details

The purpose of this clinical study is to learn about the safety and effects of the study medicine (called tilrekimig) for the potential treatment of severe asthma. Asthma is a condition that makes it challenging to breathe, which negatively impacts the quality of life of people who are affected. The study is seeking participants who: * Have a history of severe asthma for at least 12 months * Have had at least 2 asthma attacks (also known as exacerbations) within the last 12 months All participants will be given shots of study medicine or a placebo at the study clinic. The study will compare the experiences of people receiving tilrekimig to those people who receive the placebo. This will help determine if tilrekimig is safe and effective.

Key Dates

First listed
Aug 19, 2026
Start date
Aug 24, 2026
Status verified
Aug 2026
Primary completion
Jun 12, 2029
Completion
Sep 4, 2029

Study Design

Enrollment
1,100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Treatment Arm A Tilrekimig
    Tilrekimig
  • Placebo Comparator: Treatment Arm B Placebo
    Placebo

Primary Outcome Measure

Annualized asthma exacerbation rate over 52 weeks [ Time Frame: Baseline through Week 52 ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
SMS Clinical Research LLCGarlandTexas75043-
SMS Clinical Research, LLCMesquiteTexas75149-

Find similar trials in Garland, TX

By condition

Related Studies