A Study to Learn About the Study Medicine Called Tilrekimig in People With Severe Asthma
Part of paid clinical trials in Garland, Texas.
- Sponsor
- Pfizer
- Study ID
- NCT07772921
- Phase
- PHASE3
- Status
- Not Yet Recruiting
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Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 12 Years - 80 Years
- Healthy Volunteers
- Not accepted
Interventions
- tilrekimig — DRUGsubcutaneous injection
- Placebo — OTHERsubcutaneous injection
Study Details
The purpose of this clinical study is to learn about the safety and effects of the study medicine (called tilrekimig) for the potential treatment of severe asthma. Asthma is a condition that makes it challenging to breathe, which negatively impacts the quality of life of people who are affected. The study is seeking participants who: * Have a history of severe asthma for at least 12 months * Have had at least 2 asthma attacks (also known as exacerbations) within the last 12 months All participants will be given shots of study medicine or a placebo at the study clinic. The study will compare the experiences of people receiving tilrekimig to those people who receive the placebo. This will help determine if tilrekimig is safe and effective.
Key Dates
- First listed
- Aug 19, 2026
- Start date
- Aug 24, 2026
- Status verified
- Aug 2026
- Primary completion
- Jun 12, 2029
- Completion
- Sep 4, 2029
Study Design
- Enrollment
- 1,100 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: Treatment Arm A TilrekimigTilrekimig
- Placebo Comparator: Treatment Arm B PlaceboPlacebo
Primary Outcome Measure
Annualized asthma exacerbation rate over 52 weeks [ Time Frame: Baseline through Week 52 ]
Central Contacts
- Pfizer CT.gov Call Center1-800-718-1021
Locations (2)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| SMS Clinical Research LLC | Garland | Texas | 75043 | - |
| SMS Clinical Research, LLC | Mesquite | Texas | 75149 | - |
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