Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 3

Part of paid clinical trials in Guilford, Connecticut.

Sponsor
Yale University
Study ID
NCT07793383
Status
Not Yet Recruiting

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Conditions

  • Clinical Decision Support
  • Opioid Abuse (Disorder)

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Refined EMBED CDS — OTHER
    Refined EMBED CDS
  • Provider alert that nurse completed COWS — OTHER
    Provider alert that nurse completed COWS

Study Details

This study is stage 2, round 3 of a larger study which refines and optimizes the EMBED clinical decision support (CDS) to increase number of ED physicians following standard of care for the administration of buprenorphine to appropriate patients with opioid use disorder. See NCT03658642

Key Dates

First listed
Aug 28, 2026
Start date
Aug 31, 2026
Status verified
Aug 2026
Primary completion
Oct 31, 2026
Completion
Oct 31, 2026

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Refined EMBED CDS
    EMBED CDS refined based on previous results
  • Experimental: Refined EMBED plus provider alert the nurse completed COWS
    Alert to provider in Epic that the nurse completed COWS

Primary Outcome Measure

Proportion of encounters with Buprenorphine initiation in the ED [ Time Frame: Trial round start to end up to 3 months ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
Yale New Haven Shoreline Medical CenterGuilfordConnecticut06437-
Yale New Haven HospitalNew HavenConnecticut06520-
Yale New Haven Hospital- St. RaphaelNew HavenConnecticut06510-

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