Predictors of Rapid CKD Progression

Sponsor
Assiut University
Study ID
NCT07803237
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

This prospective observational cohort study aims to identify independent predictors of rapid chronic kidney disease (CKD) progression and determine its incidence among predialysis CKD patients. A total of 190 adult patients will be enrolled from the nephrology outpatient clinic and inpatient ward at Assiut University Hospitals and followed for 24 months. Rapid progression is defined as a sustained decline in eGFR \> 5 mL/min/1.73 m² per year according to KDIGO 2024 criteria. Clinical and laboratory parameters will be assessed at baseline and during follow-up to identify predictive factors

Key Dates

First listed
Sep 3, 2026
Start date
Sep 1, 2026
Status verified
Aug 2026
Primary completion
Sep 1, 2027
Completion
Mar 1, 2028

Study Design

Enrollment
190 participants (estimated)

Arms

  • Arm: Predialysis CKD Patients
    Adult patients with chronic kidney disease not receiving maintenance dialysis, followed prospectively for 24 months to assess rapid disease progression. This is an observational study with no intervention.

Primary Outcome Measure

Incidence of rapid CKD progression [ Time Frame: 24 months ]

Central Contacts

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