Intramuscular Ketamine for Suicidal Patients in the Evanston Hospital Emergency Department for Suicidal Distress

Part of paid clinical trials in Evanston, Illinois.

Sponsor
Endeavor Health
Study ID
NCT07810023
Status
Enrolling By Invitation

Conditions

  • Depression / Major Depressive Disorder
  • Suicidal
  • Suicidal Ideation
  • Suicidal Ideation and Behavior

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Ketamine (0.5 mg/kg) — DRUG
    Single intramuscular dose of ketamine (0.5 mg/kg)

Study Details

This pilot study aims to evaluate the feasibility and acceptability of administering intramuscular ketamine for the acute reduction of suicidal distress during psychiatric boarding at the Evanston Hospital ED. This study also aims to identify and describe the broader patient population who present to the Evanston Hospital ED in suicidal distress. This study includes several cohorts. A small (n=8) dosing cohort will receive an IM injection of ketamine. Additionally, an ED staff cohort and a research staff cohort can complete optional surveys to provide feedback about study procedures. Lastly, a chart review will be conducted after the completion of the study to determine the volume and patterns of patients who present to Evanston Hospital ED in suicidal distress.

Key Dates

First listed
Sep 9, 2026
Start date
Sep 10, 2026
Status verified
Sep 2026
Primary completion
Mar 31, 2027
Completion
May 31, 2027

Study Design

Enrollment
8 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Experimental: Dosing Cohort: ketamine
    Group that receives IM ketamine

Primary Outcome Measure

Difference in time spent in the ED for dosing participants vs non-dosing patients [ Time Frame: Up to 7 Days ]

Locations (1)

FacilityCityStateZIPSite coordinators
Endeavor Health Evanston HospitalEvanstonIllinois60201-

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Endeavor Health Evanston Hospital· Evanston, IL

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