Study to Refine the Effectiveness of New Generation Therapies for Suicide

Part of paid clinical trials in Columbus, Ohio.

Sponsor
Ohio State University
Study ID
NCT07818889
Status
Recruiting
Apply to this trial

Conditions

  • Suicide Attempt
  • Suicide Risk
  • Treatment Response

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Brief Cognitive Behavioral Therapy — BEHAVIORAL
    In this study, BCBT skills will be introduced in various randomly determined sequence. During the first stage, around half of participants will complete reasons for living in session 2, physiological regulation in session 3, and sleep in session 4. The other half of participants will complete these components in the reverse order: sleep in session 2, physiological regulation in session 3, and reasons for living in session 4. Treatment non-responders will continue attending BCBT sessions during Stage 2 following their 4 completed sessions in Stage 1, up to a maximum of 6 additional sessions (i.e., 10 therapy sessions total across both stages). The specific sequence of the BCBT skills used in Stage 2 will be randomly assigned.

Study Details

The purpose of this research study is to improve the effectiveness of a well-established therapy for suicidal thoughts and behaviors called Brief Cognitive Behavioral Therapy (BCBT) for Suicide Prevention.

Key Dates

First listed
Sep 14, 2026
Start date
Apr 29, 2026
Status verified
Sep 2026
Primary completion
Dec 31, 2029
Completion
Dec 31, 2029

Study Design

Enrollment
50 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
PREVENTION

Arms

  • Other: Reasons for Living
    Participants will complete reasons for living in session 2, physiological regulation in session 3, and sleep in session 4.
  • Other: Sleep
    Sleep in session 2, physiological regulation in session 3, and reasons for living in session 4.
  • Other: Cognitive Reappraisal
    Beginning at week 4, participants will be classified as treatment responders if they (1) have not engaged in any preparatory behavior or made any suicide attempts (aborted, interrupted, or actual) and (2) have an SCS-R total score ≤21. Participants who do not meet these criteria will continue BCBT and be randomized a second time to determine if cognitive reappraisal or behavioral activation components are delivered next (sessions 5-9).
  • Other: Behavioral Activation
    Beginning at week 4, participants will be classified as treatment responders if they (1) have not engaged in any preparatory behavior or made any suicide attempts (aborted, interrupted, or actual) and (2) have an SCS-R total score ≤21. Participants who do not meet these criteria will continue BCBT and be randomized a second time to determine if cognitive reappraisal or behavioral activation components are delivered next (sessions 5-9).

Primary Outcome Measure

Suicide attempts during follow-up [ Time Frame: From enrollment to the end of study completion at one year. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Department of Psychiatry and Behavioral HealthColumbusOhio43210-

Find similar trials in Columbus, OH

By research site
Department of Psychiatry and Behavioral Health· Columbus, OH

Related Studies