Prehabilitation for Improving Outcomes in Breast Cancer Patients Undergoing Neoadjuvant Systemic Treatment and Surgery

Conditions

• Breast Carcinoma

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Aerobic Exercise — OTHER
  Participate in aerobic exercise
• Bioelectric Impedance Analysis — PROCEDURE
  Ancillary studies
• Consultation — OTHER
  Attend physiatry consultation
• Educational Intervention — OTHER
  Receive prehabilitation education
• Electronic Health Record Review — OTHER
  Ancillary studies
• Nutritional Intervention — OTHER
  Receive nutritional guidance
• Physical Performance Testing — OTHER
  Ancillary studies
• Psychosocial Care — BEHAVIORAL
  Receive psychospiritual care
• Questionnaire Administration — OTHER
  Ancillary studies
• Referral — OTHER
  Receive referral(s)
• Resistance Training — OTHER
  Participate in resistance exercise
• Spiritual Therapy — PROCEDURE
  Receive psychospiritual care
• Tailored Intervention — PROCEDURE
  Receive tailored prescriptions and recommendations

Study Details

This clinical trial evaluates whether a prehabilitation program is feasible for breast cancer patients receiving neoadjuvant systemic treatment before surgery. Many people with breast cancer have problems during and after treatment. These issues can make daily activities harder and make it harder for a person to enjoy daily life. Some people with breast cancer already have other health problems, like joint pain or nerve problems, which can make these symptoms worse. Research shows that being stronger and more active before and during treatment may help people do better during cancer care and recover more easily. However, many patients do not get this type of support early enough. Prehabilitation is a program that helps patients get ready for cancer treatment and surgery. It may include help with medical care, exercise, food and nutrition, and mental health. The goal is to help patients stay as strong and healthy as possible before surgery. Starting prehabilitation during neoadjuvant systemic treatment before surgery may help breast cancer patients feel better, stay stronger and recover more easily during treatment.

Key Dates

First listed

Sep 15, 2026

Start date

Feb 24, 2027

Status verified

Sep 2026

Primary completion

Jul 24, 2029

Completion

Jul 24, 2029

Study Design

Enrollment

20 participants (estimated)

Allocation

NA

Intervention model

SINGLE_GROUP

Primary purpose

SUPPORTIVE_CARE

Arms

• Experimental: Supportive care (prehabilitation)
  See Detailed Description.

Primary Outcome Measure

Adherence (feasibility) [ Time Frame: Up to day 168 ]

Locations (2)

Find similar trials in Duarte, CA

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