Radiographic Changes in the Maxillary Sinus Following Closed Sinus Augmentation With Leukocyte Platelet Rich Fibrin

Conditions

• Partially Edentulous Maxilla

Eligibility Criteria

Sex

ALL

Age

18 Years - 85 Years

Healthy Volunteers

Not accepted

Interventions

• Leukocyte Platelet Rich Fibrin — BIOLOGICAL
  L-PRF does not directly induce bone formation within the maxillary sinus; rather, it serves as an autologous biologic scaffold that facilitates the regenerative process

Study Details

An examination of the participants mouth is done first. If they do not have enough bone to place a dental implant as a tooth replacement, and they have chosen sinus augmentation to treat this issue during implant placement a leukocyte platelet rich fibrin (L-PRF) will be performed instead of using other available options. The only difference from usual care is that L-PRF alone will be used as the bone formation material and two additional x-rays, Cone Beam Computed Tomography (CBCTs) will be taken right after the procedure and then again six months after treatment. CBCT is a special type of 3D X-ray commonly used in dentistry and oral surgery. Unlike traditional X-rays, which create flat 2D images, CBCT produces detailed 3D images of your teeth, jawbone, nerves, and nearby tissues.

Key Dates

First listed

Sep 23, 2026

Start date

Jan 31, 2027

Status verified

Sep 2026

Primary completion

Dec 1, 2028

Completion

Jan 31, 2029

Study Design

Enrollment

25 participants (estimated)

Allocation

NA

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Arms

• Experimental: Sinus Augmentation with Implant placement
  Partially edentulous patients requiring maxillary sinus augmentation for dental implant placement

Primary Outcome Measure

Maxillary Sinus Volume using 2D imaging [ Time Frame: Baseline to 6 months ]

Central Contacts

• Charles A Powell, DDS, MS
  210-567-3598
  [email protected]

Locations (1)

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