Short Versus Standard Amoxicillin for Pediatric Strep Throat
Part of paid clinical trials in Houston, Texas.
- Sponsor
- The University of Texas Health Science Center, Houston
- Study ID
- NCT07845812
- Phase
- PHASE4
- Status
- Not Yet Recruiting
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Conditions
- Group A Streptococcal (GAS) Pharyngitis
Eligibility Criteria
- Sex
- ALL
- Age
- 3 Years - 18 Years
- Healthy Volunteers
- Not accepted
Interventions
- 5 day short course antibiotic treatment — DRUGParticipants will receive oral penicillin or amoxicillin for 5 days
- 10 day standard of care antibiotic treatment — DRUGParticipants will receive oral penicillin or amoxicillin for 10 days
Study Details
The purpose of this study is to compare 5-day vs 10-day amoxicillin for strep throat in children.
Key Dates
- First listed
- Sep 29, 2026
- Start date
- Sep 28, 2026
- Status verified
- Sep 2026
- Primary completion
- Apr 28, 2029
- Completion
- Sep 28, 2029
Study Design
- Enrollment
- 1,500 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: 5 day short course antibiotic treatment
- Active Comparator: 10 day standard of care antibiotic treatment
Primary Outcome Measure
Number of participants that demonstrate resolution of throat pain and fever as reported by the participant/caregiver [ Time Frame: about 14 days after treatment initiation ]
Central Contacts
- Guliz Erdem, MD(713) 500-5806
- Gabriela Del Bianco(713) 500-5806
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 |