How many Selumetinib clinical trials are there?

99 Selumetinib clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 8 are actively recruiting participants. 51 are marked completed.

Are Selumetinib clinical trials recruiting in 2026?

Yes — 8 Selumetinib trials are actively recruiting in 2026, with 573 U.S. sites across 48 states. See the recruiting trials and the per-state site list further down this page.

What conditions is Selumetinib being studied for?

Selumetinib is being studied for Neurofibromatosis 1, Neurofibromatosis Type 1, Solid Tumours, Low Grade Glioma, Recurrent Malignant Solid Neoplasm and 263 more. The trials are grouped by indication on this page.

What phase is Selumetinib in?

Selumetinib clinical trials span 7 Phase 3, 49 Phase 2, 32 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.

Who sponsors Selumetinib clinical trials?

The lead sponsor across the most Selumetinib trials is National Cancer Institute (NCI), with 31 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Selumetinib Clinical Trials (2026): 99 Studies for Neurofibromatosis 1 & Neurofibromatosis Type 1

Creator: Hipa.ai Research
Published: 2026-05-26T17:45:46.231Z

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: September 1, 2026.

99 Selumetinib clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 76 indications (including Neurofibromatosis 1 & Neurofibromatosis Type 1) and 14,325 total planned enrollment. 7 Phase 3 Selumetinib trials and 49 Phase 2 are listed. 11 Selumetinib clinical trials are actively recruiting at 573 U.S. sites across 48 states. Most recent activity: NCT06502171 (Aug 2034).

Where to Participate: All Selumetinib Trial Sites in the U.S. (573 sites across 48 states)

Every actively recruiting Selumetinibtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

State	Facility	City	Trial	Map
AL	Children's Hospital of Alabama	Birmingham35233	NCT04166409	Map
AL	Children's of Alabama	Birmingham35294	NCT05253131	Map
AL	Childrens of Alabama	Birmingham35233	NCT06188741	Map
AL	Childrens of Alabama	Birmingham35233	NCT06502171	Map
AL	University of Alabama at Birmingham Cancer Center	Birmingham35233	NCT05564377	Map
AL	University of South Alabama Mitchell Cancer Institute	Mobile36688	NCT05564377	Map
AK	Alaska Women's Cancer Care	Anchorage99508	NCT05564377	Map
AZ	CTCA at Western Regional Medical Center	Goodyear85338	NCT05564377	Map
AZ	Kingman Regional Medical Center	Kingman86401	NCT05564377	Map
AZ	Banner Children's at Desert	Mesa85202	NCT04166409	Map
AZ	Phoenix Childrens Hospital	Phoenix85016	NCT04166409	Map
AR	NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro	Jonesboro72401	NCT05564377	Map
AR	Arkansas Children's Hospital	Little Rock72202-3591	NCT04166409	Map
CA	PCR Oncology	Arroyo Grande93420	NCT05564377	Map
CA	Mercy Cancer Center - Carmichael	Carmichael95608	NCT05564377	Map
CA	Mercy San Juan Medical Center	Carmichael95608	NCT05564377	Map
CA	Mercy Cancer Center - Elk Grove	Elk Grove95758	NCT05564377	Map
CA	UC San Diego Health System - Encinitas	Encinitas92024	NCT05564377	Map
CA	UC San Diego Moores Cancer Center	La Jolla92093	NCT05564377	Map
CA	Loma Linda University Medical Center	Loma Linda92354	NCT04166409	Map
CA	Miller Children's and Women's Hospital Long Beach	Long Beach90806	NCT04166409	Map
CA	Cedars-Sinai Medical Center	Los Angeles90048	NCT04166409	Map
CA	Cedars-Sinai Medical Center	Los Angeles90048	NCT05564377	Map
CA	Children's Hospital Los Angeles	Los Angeles90027	NCT04166409	Map
CA	Children's Hospital of Los Angeles	Los Angeles90027	NCT06188741	Map
CA	Mattel Children's Hospital UCLA	Los Angeles90095	NCT04166409	Map
CA	The Angeles Clinic and Research Institute - West Los Angeles Office	Los Angeles90025	NCT05564377	Map
CA	Kaiser Permanente-Oakland	Oakland94611	NCT04166409	Map
CA	Children's Hospital of Orange County	Orange92868	NCT04166409	Map
CA	Children's Hospital of Orange County	Orange92868	NCT05564377	Map
CA	Saint Joseph Hospital - Orange	Orange92868	NCT05564377	Map
CA	Lucile Packard Children's Hospital Stanford University	Palo Alto94304	NCT04166409	Map
CA	Stanford Cancer Institute Palo Alto	Palo Alto94304	NCT05564377	Map
CA	Stanford University	Palo Alto94304	NCT06188741	Map
CA	VA Palo Alto Health Care System	Palo Alto94304	NCT05564377	Map
CA	Mercy Cancer Center - Rocklin	Rocklin95765	NCT05564377	Map
CA	Mercy Cancer Center - Sacramento	Sacramento95816	NCT05564377	Map
CA	Rady Children's Hospital - San Diego	San Diego92123	NCT04166409	Map
CA	Sharp Memorial Hospital	San Diego92123	NCT05564377	Map
CA	UC San Diego Medical Center - Hillcrest	San Diego92103	NCT05564377	Map
CA	UCSF Medical Center-Mission Bay	San Francisco94158	NCT04166409	Map
CA	Saint John's Cancer Institute	Santa Monica90404	NCT05564377	Map
CA	Woodland Memorial Hospital	Woodland95695	NCT05564377	Map
CO	Children's Hospital Colorado	Aurora80045	NCT04166409	Map
CO	UCHealth University of Colorado Hospital	Aurora80045	NCT05564377	Map
CO	Cancer Care and Hematology-Fort Collins	Fort Collins80528	NCT05564377	Map
CO	Poudre Valley Hospital	Fort Collins80524	NCT05564377	Map
CO	UCHealth Greeley Hospital	Greeley80631	NCT05564377	Map
CO	Medical Center of the Rockies	Loveland80538	NCT05564377	Map
CT	Connecticut Children's Medical Center	Hartford06106	NCT04166409	Map
CT	Yale University	New Haven06520	NCT04166409	Map
DE	Helen F Graham Cancer Center	Newark19713	NCT05564377	Map
DE	Medical Oncology Hematology Consultants PA	Newark19713	NCT05564377	Map
DE	Alfred I duPont Hospital for Children	Wilmington19803	NCT04166409	Map
DC	Children's National Hospital	Washington D.C.20010	NCT06188741	Map
DC	Children's National Hospital	Washington D.C.20010	NCT06502171	Map
DC	Children's National Hospital	Washington D.C.20010	NCT06735820	Map
DC	Children's National Medical Center	Washington D.C.20010	NCT04166409	Map
FL	UM Sylvester Comprehensive Cancer Center at Aventura	Aventura33180	NCT05564377	Map
FL	UM Sylvester Comprehensive Cancer Center at Coral Gables	Coral Gables33146	NCT05564377	Map
FL	UM Sylvester Comprehensive Cancer Center at Deerfield Beach	Deerfield Beach33442	NCT05564377	Map
FL	Broward Health Medical Center	Fort Lauderdale33316	NCT05564377	Map
FL	Golisano Children's Hospital of Southwest Florida	Fort Myers33908	NCT04166409	Map
FL	UF Health Cancer Institute - Gainesville	Gainesville32610	NCT05564377	Map
FL	Memorial Regional Hospital/Joe DiMaggio Children's Hospital	Hollywood33021	NCT04166409	Map
FL	Mayo Clinic in Florida	Jacksonville32224-9980	NCT05564377	Map
FL	Nemours Children's Clinic-Jacksonville	Jacksonville32207	NCT04166409	Map
FL	Nicklaus Children's Hospital	Miami33155	NCT04166409	Map
FL	UM Sylvester Comprehensive Cancer Center at Kendall	Miami33176	NCT05564377	Map
FL	University of Miami Miller School of Medicine-Sylvester Cancer Center	Miami33136	NCT05564377	Map
FL	University of Miami Sylvester Comprehensive Cancer Center at Sole Mia	North Miami33181	NCT05564377	Map
FL	AdventHealth Orlando	Orlando32803	NCT04166409	Map
FL	Arnold Palmer Hospital for Children	Orlando32806	NCT04166409	Map
FL	Nemours Children's Hospital	Orlando32827	NCT04166409	Map
FL	Nemours Children's Clinic - Pensacola	Pensacola32504	NCT04166409	Map
FL	UM Sylvester Comprehensive Cancer Center at Plantation	Plantation33324	NCT05564377	Map
FL	Johns Hopkins All Children's Hospital	St. Petersburg33701	NCT04166409	Map
FL	Saint Joseph's Hospital/Children's Hospital-Tampa	Tampa33607	NCT04166409	Map
GA	Children's Healthcare of Atlanta - Arthur M Blank Hospital	Atlanta30329	NCT04166409	Map
HI	Hawaii Cancer Care - Westridge	‘Aiea96701	NCT05564377	Map
HI	Pali Momi Medical Center	‘Aiea96701	NCT05564377	Map
HI	The Queen's Medical Center - West Oahu	‘Ewa Beach96706	NCT05564377	Map
HI	Hawaii Cancer Care Inc - Waterfront Plaza	Honolulu96813	NCT05564377	Map
HI	Kapiolani Medical Center for Women and Children	Honolulu96826	NCT04166409	Map
HI	Kapiolani Medical Center for Women and Children	Honolulu96826	NCT05564377	Map
HI	Queen's Cancer Cenrer - POB I	Honolulu96813	NCT05564377	Map
HI	Queen's Cancer Center - Kuakini	Honolulu96817	NCT05564377	Map
HI	Queen's Medical Center	Honolulu96813	NCT05564377	Map
HI	Straub Clinic and Hospital	Honolulu96813	NCT05564377	Map
HI	University of Hawaii Cancer Center	Honolulu96813	NCT05564377	Map
ID	Saint Alphonsus Cancer Care Center-Boise	Boise83706	NCT05564377	Map
ID	Saint Luke's Cancer Institute - Boise	Boise83712	NCT04166409	Map
ID	Saint Luke's Cancer Institute - Boise	Boise83712	NCT05564377	Map
ID	Saint Alphonsus Cancer Care Center-Caldwell	Caldwell83605	NCT05564377	Map
ID	Kootenai Health - Coeur d'Alene	Coeur d'Alene83814	NCT05564377	Map
ID	Saint Luke's Cancer Institute - Fruitland	Fruitland83619	NCT05564377	Map
ID	Saint Luke's Cancer Institute - Meridian	Meridian83642	NCT05564377	Map
ID	Saint Alphonsus Cancer Care Center-Nampa	Nampa83687	NCT05564377	Map
ID	Saint Luke's Cancer Institute - Nampa	Nampa83687	NCT05564377	Map
ID	Kootenai Clinic Cancer Services - Post Falls	Post Falls83854	NCT05564377	Map
ID	Kootenai Clinic Cancer Services - Sandpoint	Sandpoint83864	NCT05564377	Map
ID	Saint Luke's Cancer Institute - Twin Falls	Twin Falls83301	NCT05564377	Map
IL	Advocate Good Shepherd Hospital	Barrington60010	NCT05564377	Map
IL	Illinois CancerCare-Bloomington	Bloomington61704	NCT05564377	Map
IL	Illinois CancerCare-Canton	Canton61520	NCT05564377	Map
IL	SIH Cancer Institute	Carterville62918	NCT05564377	Map
IL	Illinois CancerCare-Carthage	Carthage62321	NCT05564377	Map
IL	Centralia Oncology Clinic	Centralia62801	NCT05564377	Map
IL	Advocate Illinois Masonic Medical Center	Chicago60657	NCT05564377	Map
IL	John H Stroger Jr Hospital of Cook County	Chicago60612	NCT05564377	Map
IL	Lurie Children's Hospital of Chicago	Chicago60611	NCT06188741	Map
IL	Lurie Children's Hospital-Chicago	Chicago60611	NCT04166409	Map
IL	Mount Sinai Hospital Medical Center	Chicago60608	NCT05564377	Map
IL	Northwestern University	Chicago60611	NCT05564377	Map
IL	The University of Chicago	Chicago60637	NCT03326310	Map
IL	University of Chicago	Chicago63637	NCT06188741	Map
IL	University of Chicago Comprehensive Cancer Center	Chicago60637	NCT04166409	Map
IL	University of Chicago Comprehensive Cancer Center	Chicago60637	NCT05564377	Map
IL	University of Illinois	Chicago60612	NCT04166409	Map
IL	University of Illinois	Chicago60612	NCT05564377	Map
IL	AMG Crystal Lake - Oncology	Crystal Lake60014	NCT05564377	Map
IL	Carle at The Riverfront	Danville61832	NCT05564377	Map
IL	Cancer Care Specialists of Illinois - Decatur	Decatur62526	NCT05564377	Map
IL	Decatur Memorial Hospital	Decatur62526	NCT05564377	Map
IL	Northwestern Medicine Cancer Center Kishwaukee	DeKalb60115	NCT05564377	Map
IL	Illinois CancerCare-Dixon	Dixon61021	NCT05564377	Map
IL	Advocate Good Samaritan Hospital	Downers Grove60515	NCT05564377	Map
IL	Carle Physician Group-Effingham	Effingham62401	NCT05564377	Map
IL	Crossroads Cancer Center	Effingham62401	NCT05564377	Map
IL	Advocate Sherman Hospital	Elgin60123	NCT05564377	Map
IL	Illinois CancerCare-Eureka	Eureka61530	NCT05564377	Map
IL	NorthShore University HealthSystem-Evanston Hospital	Evanston60201	NCT05564377	Map
IL	Illinois CancerCare-Galesburg	Galesburg61401	NCT05564377	Map
IL	Northwestern Medicine Cancer Center Delnor	Geneva60134	NCT05564377	Map
IL	NorthShore University HealthSystem-Glenbrook Hospital	Glenview60026	NCT05564377	Map
IL	Northwestern Medicine Glenview Outpatient Center	Glenview60026	NCT05564377	Map
IL	Northwestern Medicine Grayslake Outpatient Center	Grayslake60030	NCT05564377	Map
IL	Ingalls Memorial Hospital	Harvey60426	NCT05564377	Map
IL	Advocate South Suburban Hospital	Hazel Crest60429	NCT05564377	Map
IL	NorthShore University HealthSystem-Highland Park Hospital	Highland Park60035	NCT05564377	Map
IL	Illinois CancerCare-Kewanee Clinic	Kewanee61443	NCT05564377	Map
IL	Northwestern Medicine Lake Forest Hospital	Lake Forest60045	NCT05564377	Map
IL	AMG Libertyville - Oncology	Libertyville60048	NCT05564377	Map
IL	Condell Memorial Hospital	Libertyville60048	NCT05564377	Map
IL	Illinois CancerCare-Macomb	Macomb61455	NCT05564377	Map
IL	Carle Physician Group-Mattoon/Charleston	Mattoon61938	NCT05564377	Map
IL	Loyola University Medical Center	Maywood60153	NCT05564377	Map
IL	SSM Health Good Samaritan	Mount Vernon62864	NCT05564377	Map
IL	UC Comprehensive Cancer Center at Silver Cross	New Lenox60451	NCT05564377	Map
IL	Carle BroMenn Medical Center	Normal61761	NCT05564377	Map
IL	Carle Cancer Institute Normal	Normal61761	NCT05564377	Map
IL	Cancer Care Center of O'Fallon	O'Fallon62269	NCT05564377	Map
IL	Advocate Christ Medical Center	Oak Lawn60453-2699	NCT05564377	Map
IL	Northwestern Medicine Orland Park	Orland Park60462	NCT05564377	Map
IL	University of Chicago Medicine-Orland Park	Orland Park60462	NCT05564377	Map
IL	Illinois CancerCare-Ottawa Clinic	Ottawa61350	NCT05564377	Map
IL	Advocate Lutheran General Hospital	Park Ridge60068	NCT05564377	Map
IL	Illinois CancerCare-Pekin	Pekin61554	NCT05564377	Map
IL	Illinois CancerCare-Peoria	Peoria61615	NCT05564377	Map
IL	OSF Children's Hospital of Illinois	Peoria61637	NCT04166409	Map
IL	Illinois CancerCare-Peru	Peru61354	NCT05564377	Map
IL	Illinois CancerCare-Princeton	Princeton61356	NCT05564377	Map
IL	Mercyhealth Cancer Institute - Rockford	Rockford61114	NCT05564377	Map
IL	Memorial Hospital East	Shiloh62269	NCT05564377	Map
IL	Southern Illinois University School of Medicine	Springfield62702	NCT04166409	Map
IL	Southern Illinois University School of Medicine	Springfield62702	NCT05564377	Map
IL	Springfield Clinic	Springfield62702	NCT05564377	Map
IL	Springfield Memorial Hospital	Springfield62781	NCT05564377	Map
IL	Carle Cancer Center	Urbana61801	NCT05564377	Map
IL	Northwestern Medicine Cancer Center Warrenville	Warrenville60555	NCT05564377	Map
IL	Illinois CancerCare - Washington	Washington61571	NCT05564377	Map
IN	UChicago Medicine Northwest Indiana	Crown Point46307	NCT05564377	Map
IN	Ascension Saint Vincent Indianapolis Hospital	Indianapolis46260	NCT04166409	Map
IN	Riley Hospital for Children	Indianapolis46202	NCT04166409	Map
IN	Riley Hospital for Children/Indiana University	Indianapolis46202	NCT06188741	Map
IN	Woodland Cancer Care Center	Michigan City46360	NCT05564377	Map
IA	UI Health Care Mission Cancer and Blood - Ankeny Clinic	Ankeny50023	NCT05564377	Map
IA	Mercy Hospital	Cedar Rapids52403	NCT05564377	Map
IA	Oncology Associates at Mercy Medical Center	Cedar Rapids52403	NCT05564377	Map
IA	Blank Children's Hospital	Des Moines50309	NCT04166409	Map
IA	Mercy Medical Center - Des Moines	Des Moines50314	NCT05564377	Map
IA	UI Health Care Mission Cancer and Blood - Des Moines Clinic	Des Moines50309	NCT05564377	Map
IA	UI Health Care Mission Cancer and Blood - Laurel Clinic	Des Moines50314	NCT05564377	Map
IA	University of Iowa/Holden Comprehensive Cancer Center	Iowa City52242	NCT04166409	Map
IA	UI Health Care Mission Cancer and Blood - Waukee Clinic	Waukee50263	NCT05564377	Map
KY	CommonSpirit Saint Joseph Medical Center - East Lexington	Lexington40509	NCT05564377	Map
KY	University of Kentucky/Markey Cancer Center	Lexington40536	NCT04166409	Map
KY	University of Kentucky/Markey Cancer Center	Lexington40536	NCT05564377	Map
KY	Norton Children's Hospital	Louisville40202	NCT04166409	Map
LA	Children's Hospital New Orleans	New Orleans70118	NCT04166409	Map
LA	Ochsner Medical Center Jefferson	New Orleans70121	NCT05564377	Map
ME	Harold Alfond Center for Cancer Care	Augusta04330	NCT05564377	Map
ME	Eastern Maine Medical Center	Bangor04401	NCT04166409	Map
ME	Lafayette Family Cancer Center-EMMC	Brewer04412	NCT05564377	Map
ME	Maine Children's Cancer Program	Scarborough04074	NCT04166409	Map
ME	MaineHealth Maine Medical Center- Scarborough	Scarborough04074	NCT05564377	Map
ME	MaineHealth Cancer Care and IV Therapy - South Portland	South Portland04106	NCT05564377	Map
MD	Johns Hopkins University	Baltimore21231	NCT06188741	Map
MD	Johns Hopkins University/Sidney Kimmel Cancer Center	Baltimore21287	NCT04166409	Map
MD	University of Maryland/Greenebaum Cancer Center	Baltimore21201	NCT05564377	Map
MD	National Cancer Institute/ National Institutes of Health	Bethesda20892	NCT06188741	Map
MD	National Institutes of Health Clinical Center	Bethesda20892	NCT05564377	Map
MD	Walter Reed National Military Medical Center	Bethesda20889-5600	NCT04166409	Map
MD	Walter Reed National Military Medical Center	Bethesda20889-5600	NCT05564377	Map
MD	UPMC Western Maryland	Cumberland21502	NCT05564377	Map
MA	Boston Children's Hospital	Boston02115	NCT06188741	Map
MA	Boston Children's Hospital	Boston02115	NCT06502171	Map
MA	Dana-Farber Cancer Institute	Boston02215	NCT05564377	Map
MA	Tufts Medical Center	Boston02111	NCT05564377	Map
MA	Baystate Medical Center	Springfield01199	NCT05564377	Map
MA	Tufts Medical Center Cancer Center Stoneham	Stoneham02180	NCT05564377	Map
MI	C S Mott Children's Hospital	Ann Arbor48109	NCT04166409	Map
MI	Trinity Health Saint Joseph Mercy Hospital Ann Arbor	Ann Arbor48106	NCT05564377	Map
MI	University of Michigan Rogel Cancer Center	Ann Arbor48109	NCT05564377	Map
MI	Bronson Battle Creek	Battle Creek49017	NCT05564377	Map
MI	Trinity Health IHA Medical Group Hematology Oncology - Brighton	Brighton48114	NCT05564377	Map
MI	Trinity Health Medical Center - Brighton	Brighton48114	NCT05564377	Map
MI	University of Michigan - Brighton Center for Specialty Care	Brighton48116	NCT05564377	Map
MI	Trinity Health IHA Medical Group Hematology Oncology - Canton	Canton48188	NCT05564377	Map
MI	Trinity Health Medical Center - Canton	Canton48188	NCT05564377	Map
MI	Chelsea Hospital	Chelsea48118	NCT05564377	Map
MI	Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital	Chelsea48118	NCT05564377	Map
MI	Corewell Health Dearborn Hospital	Dearborn48124	NCT05564377	Map
MI	Children's Hospital of Michigan	Detroit48201	NCT04166409	Map
MI	OSF Saint Francis Hospital and Medical Group	Escanaba49829	NCT05564377	Map
MI	Corewell Health Farmington Hills Hospital	Farmington Hills48336	NCT05564377	Map
MI	Cancer Hematology Centers - Flint	Flint48503	NCT05564377	Map
MI	Genesys Hurley Cancer Institute	Flint48503	NCT05564377	Map
MI	Hurley Medical Center	Flint48503	NCT05564377	Map
MI	Corewell Health Grand Rapids Hospitals - Butterworth Hospital	Grand Rapids49503	NCT05564377	Map
MI	Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital	Grand Rapids49503	NCT04166409	Map
MI	Beacon Kalamazoo	Kalamazoo49048	NCT05564377	Map
MI	Beacon Kalamazoo Cancer Center	Kalamazoo49009	NCT05564377	Map
MI	Bronson Methodist Hospital	Kalamazoo49007	NCT05564377	Map
MI	West Michigan Cancer Center	Kalamazoo49007	NCT05564377	Map
MI	University of Michigan Health - Sparrow Lansing	Lansing48912	NCT05564377	Map
MI	Trinity Health Saint Mary Mercy Livonia Hospital	Livonia48154	NCT05564377	Map
MI	Henry Ford Saint John Hospital - Macomb Medical	Macomb48044	NCT05564377	Map
MI	Corewell Health Lakeland Hospitals - Niles Hospital	Niles49120	NCT05564377	Map
MI	Michigan Healthcare Professionals Pontiac	Pontiac48341	NCT05564377	Map
MI	Trinity Health Saint Joseph Mercy Oakland Hospital	Pontiac48341	NCT05564377	Map
MI	Corewell Health Reed City Hospital	Reed City49677	NCT05564377	Map
MI	Corewell Health Children's	Royal Oak48073	NCT05564377	Map
MI	Corewell Health William Beaumont University Hospital	Royal Oak48073	NCT05564377	Map
MI	MyMichigan Medical Center Saginaw	Saginaw48601	NCT05564377	Map
MI	Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center	Saint Joseph49085	NCT05564377	Map
MI	Corewell Health Lakeland Hospitals - Saint Joseph Hospital	Saint Joseph49085	NCT05564377	Map
MI	MyMichigan Medical Center Tawas	Tawas City48764	NCT05564377	Map
MI	Munson Medical Center	Traverse City49684	NCT05564377	Map
MI	Corewell Health Beaumont Troy Hospital	Troy48085	NCT05564377	Map
MI	University of Michigan Health - West	Wyoming49519	NCT05564377	Map
MI	Huron Gastroenterology PC	Ypsilanti48106	NCT05564377	Map
MI	Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus	Ypsilanti48197	NCT05564377	Map
MN	Sanford Joe Lueken Cancer Center	Bemidji56601	NCT05564377	Map
MN	Mercy Hospital	Coon Rapids55433	NCT05564377	Map
MN	Essentia Health - Deer River Clinic	Deer River56636	NCT05564377	Map
MN	Essentia Health Cancer Center	Duluth55805	NCT05564377	Map
MN	Fairview Southdale Hospital	Edina55435	NCT05564377	Map
MN	Essentia Health Hibbing Clinic	Hibbing55746	NCT05564377	Map
MN	Fairview Clinics and Surgery Center Maple Grove	Maple Grove55369	NCT05564377	Map
MN	Saint John's Hospital - Healtheast	Maplewood55109	NCT05564377	Map
MN	Abbott-Northwestern Hospital	Minneapolis55407	NCT05564377	Map
MN	Children's Hospitals and Clinics of Minnesota - Minneapolis	Minneapolis55404	NCT04166409	Map
MN	University of Minnesota/Masonic Cancer Center	Minneapolis55455	NCT04166409	Map
MN	Mayo Clinic	Rochester55905	NCT06188741	Map
MN	Mayo Clinic in Rochester	Rochester55905	NCT04166409	Map
MN	Mayo Clinic in Rochester	Rochester55905	NCT05564377	Map
MN	Park Nicollet Clinic - Saint Louis Park	Saint Louis Park55416	NCT05564377	Map
MN	Regions Hospital	Saint Paul55101	NCT05564377	Map
MN	United Hospital	Saint Paul55102	NCT05564377	Map
MN	Essentia Health Sandstone	Sandstone55072	NCT05564377	Map
MN	Essentia Health Virginia Clinic	Virginia55792	NCT05564377	Map
MS	Baptist Memorial Hospital and Cancer Center-Golden Triangle	Columbus39705	NCT05564377	Map
MS	Baptist Cancer Center-Grenada	Grenada38901	NCT05564377	Map
MS	University of Mississippi Medical Center	Jackson39216	NCT04166409	Map
MS	Baptist Memorial Hospital and Cancer Center-Union County	New Albany38652	NCT05564377	Map
MS	Baptist Memorial Hospital and Cancer Center-Oxford	Oxford38655	NCT05564377	Map
MS	Baptist Memorial Hospital and Cancer Center-Desoto	Southhaven38671	NCT05564377	Map
MO	Saint Francis Medical Center	Cape Girardeau63703	NCT05564377	Map
MO	Saint Luke's Hospital	Chesterfield63017	NCT05564377	Map
MO	Siteman Cancer Center at Saint Peters Hospital	City of Saint Peters63376	NCT05564377	Map
MO	Siteman Cancer Center at West County Hospital	Creve Coeur63141	NCT05564377	Map
MO	Parkland Health Center - Farmington	Farmington63640	NCT05564377	Map
MO	Children's Mercy Hospitals and Clinics	Kansas City64108	NCT04166409	Map
MO	Heartland Regional Medical Center	Saint Joseph64506	NCT05564377	Map
MO	Sainte Genevieve County Memorial Hospital	Sainte Genevieve63670	NCT05564377	Map
MO	CoxHealth South Hospital	Springfield65807	NCT05564377	Map
MO	Mercy Hospital Springfield	Springfield65804	NCT05564377	Map
MO	Cardinal Glennon Children's Medical Center	St Louis63104	NCT04166409	Map
MO	Mercy Hospital Saint Louis	St Louis63141	NCT05564377	Map
MO	Mercy Hospital South	St Louis63128	NCT05564377	Map
MO	Missouri Baptist Medical Center	St Louis63131	NCT05564377	Map
MO	Siteman Cancer Center at Christian Hospital	St Louis63136	NCT05564377	Map
MO	Siteman Cancer Center-South County	St Louis63129	NCT05564377	Map
MO	Washington University - St. Louis	St Louis63110	NCT06188741	Map
MO	Washington University School of Medicine	St Louis63110	NCT04166409	Map
MO	Washington University School of Medicine	St Louis63110	NCT05564377	Map
MO	Missouri Baptist Sullivan Hospital	Sullivan63080	NCT05564377	Map
MT	Community Hospital of Anaconda	Anaconda59711	NCT05564377	Map
MT	Billings Clinic Cancer Center	Billings59101	NCT05564377	Map
MT	Bozeman Health Deaconess Hospital	Bozeman59715	NCT05564377	Map
MT	Benefis Sletten Cancer Institute	Great Falls59405	NCT05564377	Map
MT	Logan Health Medical Center	Kalispell59901	NCT05564377	Map
MT	Community Medical Center	Missoula59804	NCT05564377	Map
NE	Children's Hospital and Medical Center of Omaha	Omaha68114	NCT04166409	Map
NE	University of Nebraska Medical Center	Omaha68198	NCT04166409	Map
NV	Alliance for Childhood Diseases/Cure 4 the Kids Foundation	Las Vegas89135	NCT05564377	Map
NV	OptumCare Cancer Care at Charleston	Las Vegas89102	NCT05564377	Map
NV	OptumCare Cancer Care at Fort Apache	Las Vegas89183	NCT05564377	Map
NV	Summerlin Hospital Medical Center	Las Vegas89144	NCT05564377	Map
NV	Renown Regional Medical Center	Reno89502	NCT05564377	Map
NJ	Hunterdon Medical Center	Flemington08822	NCT05564377	Map
NJ	Monmouth Medical Center Southern Campus	Lakewood08701	NCT05564377	Map
NJ	Cooperman Barnabas Medical Center	Livingston07039	NCT05564377	Map
NJ	Monmouth Medical Center	Long Branch07740	NCT05564377	Map
NJ	Memorial Sloan Kettering Monmouth	Middletown07748	NCT05564377	Map
NJ	Morristown Medical Center	Morristown07960	NCT04166409	Map
NJ	Rutgers Cancer Institute of New Jersey	New Brunswick08903	NCT05564377	Map
NJ	Sidney Kimmel Cancer Center Washington Township	Sewell08080	NCT05564377	Map
NJ	Robert Wood Johnson University Hospital Somerset	Somerville08876	NCT05564377	Map
NJ	Community Medical Center	Toms River08755	NCT05564377	Map
NM	University of New Mexico Cancer Center	Albuquerque87106	NCT05564377	Map
NY	Albany Medical Center	Albany12208	NCT04166409	Map
NY	Roswell Park Cancer Institute	Buffalo14263	NCT04166409	Map
NY	Roswell Park Cancer Institute	Buffalo14263	NCT05564377	Map
NY	Memorial Sloan Kettering Commack	Commack11725	NCT05564377	Map
NY	Memorial Sloan Kettering Westchester	Harrison10604	NCT05564377	Map
NY	NYU Langone Hospital - Long Island	Mineola11501	NCT04166409	Map
NY	NYU Langone Hospital - Long Island	Mineola11501	NCT05564377	Map
NY	The Steven and Alexandra Cohen Children's Medical Center of New York	New Hyde Park11040	NCT04166409	Map
NY	Laura and Isaac Perlmutter Cancer Center at NYU Langone	New York10016	NCT04166409	Map
NY	Laura and Isaac Perlmutter Cancer Center at NYU Langone	New York10016	NCT05564377	Map
NY	Memorial Sloan Kettering Cancer Center	New York10065	NCT04166409	Map
NY	Memorial Sloan Kettering Cancer Center	New York10065	NCT05564377	Map
NY	Mount Sinai Hospital	New York10029	NCT05564377	Map
NY	State University of New York Upstate Medical University	Syracuse13210	NCT04166409	Map
NY	State University of New York Upstate Medical University	Syracuse13210	NCT05564377	Map
NY	Montefiore Medical Center - Moses Campus	The Bronx10467	NCT05564377	Map
NY	Montefiore Medical Center-Einstein Campus	The Bronx10461	NCT05564377	Map
NY	Montefiore Medical Center-Weiler Hospital	The Bronx10461	NCT05564377	Map
NY	New York Medical College	Valhalla10595	NCT04166409	Map
NC	Cone Health MedCenter Asheboro	Asheboro27205	NCT05564377	Map
NC	Cone Health Cancer Center at Alamance Regional	Burlington27215	NCT05564377	Map
NC	UNC Lineberger Comprehensive Cancer Center	Chapel Hill27599	NCT04166409	Map
NC	Carolinas Medical Center/Levine Cancer Institute	Charlotte28203	NCT04166409	Map
NC	Southeastern Medical Oncology Center-Clinton	Clinton28328	NCT05564377	Map
NC	Duke University Medical Center	Durham27710	NCT04166409	Map
NC	Duke University Medical Center	Durham27710	NCT05564377	Map
NC	Southeastern Medical Oncology Center-Goldsboro	Goldsboro27534	NCT05564377	Map
NC	Cone Health Cancer Center	Greensboro27403	NCT05564377	Map
NC	Cone Health Cancer Center at Drawbridge Parkway	Greensboro27410	NCT05564377	Map
NC	East Carolina University	Greenville27834	NCT04166409	Map
NC	Hayworth Cancer Center	High Point27262	NCT05564377	Map
NC	Southeastern Medical Oncology Center-Jacksonville	Jacksonville28546	NCT05564377	Map
NC	Duke Women's Cancer Care Raleigh	Raleigh27607	NCT05564377	Map
NC	Annie Penn Memorial Hospital	Reidsville27320	NCT05564377	Map
NC	Wake Forest University Health Sciences	Winston-Salem27157	NCT04166409	Map
NC	Wake Forest University Health Sciences	Winston-Salem27157	NCT05564377	Map
ND	Sanford Bismarck Medical Center	Bismarck58501	NCT05564377	Map
ND	Sanford Broadway Medical Center	Fargo58122	NCT04166409	Map
ND	Sanford Broadway Medical Center	Fargo58122	NCT05564377	Map
ND	Sanford Roger Maris Cancer Center	Fargo58122	NCT05564377	Map
OH	Children's Hospital Medical Center of Akron	Akron44308	NCT04166409	Map
OH	OhioHealth O'Bleness Hospital	Athens45701	NCT05564377	Map
OH	UH Seidman Cancer Center at UH Avon Health Center	Avon44011	NCT05564377	Map
OH	UHHS-Chagrin Highlands Medical Center	Beachwood44122	NCT05564377	Map
OH	Strecker Cancer Center-Belpre	Belpre45714	NCT05564377	Map
OH	Aultman Health Foundation	Canton44710	NCT05564377	Map
OH	Miami Valley Hospital South	Centerville45459	NCT05564377	Map
OH	Adena Regional Medical Center	Chillicothe45601	NCT05564377	Map
OH	Cincinnati Children's Hospital Medical Center	Cincinnati45229	NCT04166409	Map
OH	Cincinnati Children's Hospital Medical Center	Cincinnati45229-3039	NCT06502171	Map
OH	Cincinnati Childrens Hospital Medical Center	Cincinnati45229-	NCT06188741	Map
OH	Good Samaritan Hospital - Cincinnati	Cincinnati45220	NCT05564377	Map
OH	Case Western Reserve University	Cleveland44106	NCT05564377	Map
OH	Cleveland Clinic Foundation	Cleveland44195	NCT05564377	Map
OH	Rainbow Babies and Childrens Hospital	Cleveland44106	NCT04166409	Map
OH	Columbus Oncology and Hematology Associates Inc	Columbus43214	NCT05564377	Map
OH	Doctors Hospital	Columbus43228	NCT05564377	Map
OH	Grant Medical Center	Columbus43215	NCT05564377	Map
OH	Mount Carmel East Hospital	Columbus43213	NCT05564377	Map
OH	Nationwide Children's Hospital	Columbus43205	NCT04166409	Map
OH	Ohio State University Comprehensive Cancer Center	Columbus43210	NCT05564377	Map
OH	Riverside Methodist Hospital	Columbus43214	NCT05564377	Map
OH	The Mark H Zangmeister Center	Columbus43219	NCT05564377	Map
OH	Dayton Children's Hospital	Dayton45404	NCT04166409	Map
OH	Miami Valley Hospital	Dayton45409	NCT05564377	Map
OH	Miami Valley Hospital North	Dayton45415	NCT05564377	Map
OH	Premier Blood and Cancer Center	Dayton45409	NCT05564377	Map
OH	Delaware Health Center-Grady Cancer Center	Delaware43015	NCT05564377	Map
OH	Grady Memorial Hospital	Delaware43015	NCT05564377	Map
OH	Columbus Oncology and Hematology Associates	Dublin43016	NCT05564377	Map
OH	Dublin Methodist Hospital	Dublin43016	NCT05564377	Map
OH	Atrium Medical Center-Middletown Regional Hospital	Franklin45005-1066	NCT05564377	Map
OH	Miami Valley Cancer Care and Infusion	Greenville45331	NCT05564377	Map
OH	Kettering Medical Center	Kettering45429	NCT05564377	Map
OH	Fairfield Medical Center	Lancaster43130	NCT05564377	Map
OH	OhioHealth Mansfield Hospital	Mansfield44903	NCT05564377	Map
OH	OhioHealth Marion General Hospital	Marion43302	NCT05564377	Map
OH	Memorial Hospital	Marysville43040	NCT05564377	Map
OH	UH Seidman Cancer Center at Lake Health Mentor Campus	Mentor44060	NCT05564377	Map
OH	Knox Community Hospital	Mount Vernon43050	NCT05564377	Map
OH	Licking Memorial Hospital	Newark43055	NCT05564377	Map
OH	Mercy Health - Perrysburg Hospital	Perrysburg43551	NCT05564377	Map
OH	OhioHealth Pickerington Methodist Hospital	Pickerington43147	NCT05564377	Map
OH	Southern Ohio Medical Center	Portsmouth45662	NCT05564377	Map
OH	Springfield Regional Cancer Center	Springfield45504	NCT05564377	Map
OH	Springfield Regional Medical Center	Springfield45504	NCT05564377	Map
OH	Mercy Health - Saint Anne Hospital	Toledo43623	NCT05564377	Map
OH	Upper Valley Medical Center	Troy45373	NCT05564377	Map
OH	OhioHealth Westerville Medical Campus/Westerville Cancer Center	Westerville43082	NCT05564377	Map
OH	Saint Ann's Hospital	Westerville43081	NCT05564377	Map
OH	Genesis Healthcare System Cancer Care Center	Zanesville43701	NCT05564377	Map
OK	University of Oklahoma Health Sciences Center	Oklahoma City73104	NCT04166409	Map
OK	University of Oklahoma Health Sciences Center	Oklahoma City73104	NCT05564377	Map
OR	Providence Newberg Medical Center	Newberg97132	NCT05564377	Map
OR	Saint Alphonsus Cancer Care Center-Ontario	Ontario97914	NCT05564377	Map
OR	Providence Willamette Falls Medical Center	Oregon City97045	NCT05564377	Map
OR	Oregon Health and Science University	Portland97239	NCT04166409	Map
OR	Oregon Health and Science University	Portland97239	NCT05564377	Map
OR	Providence Portland Medical Center	Portland97213	NCT05564377	Map
OR	Providence Saint Vincent Medical Center	Portland97225	NCT05564377	Map
PA	Lehigh Valley Hospital-Cedar Crest	Allentown18103	NCT05564377	Map
PA	UPMC Altoona	Altoona16601	NCT05564377	Map
PA	Lehigh Valley Hospital - Muhlenberg	Bethlehem18017	NCT05564377	Map
PA	Geisinger Medical Center	Danville17822	NCT04166409	Map
PA	Pocono Medical Center	East Stroudsburg18301	NCT05564377	Map
PA	UPMC Hillman Cancer Center Erie	Erie16505	NCT05564377	Map
PA	UPMC Cancer Centers - Arnold Palmer Pavilion	Greensburg15601	NCT05564377	Map
PA	Lehigh Valley Hospital-Hazleton	Hazleton18201	NCT05564377	Map
PA	Penn State Children's Hospital	Hershey17033	NCT04166409	Map
PA	UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion	Mechanicsburg17050	NCT05564377	Map
PA	Riddle Memorial Hospital	Media19063	NCT05564377	Map
PA	UPMC Hillman Cancer Center - Monroeville	Monroeville15146	NCT05564377	Map
PA	Paoli Memorial Hospital	Paoli19301	NCT05564377	Map
PA	Children's Hospital of Philadelphia	Philadelphia19104	NCT04166409	Map
PA	Children's Hospital of Philadelphia	Philadelphia19104	NCT06188741	Map
PA	Children's Hospital of Philadelphia	Philadelphia19104	NCT06502171	Map
PA	Fox Chase Cancer Center	Philadelphia19111	NCT05564377	Map
PA	Pennsylvania Hospital	Philadelphia19107	NCT05564377	Map
PA	Saint Christopher's Hospital for Children	Philadelphia19134	NCT04166409	Map
PA	Thomas Jefferson University Hospital	Philadelphia19107	NCT05564377	Map
PA	Children's Hospital of Pittsburgh of UPMC	Pittsburgh15224	NCT04166409	Map
PA	UPMC Hillman Cancer Center	Pittsburgh15232	NCT05564377	Map
PA	UPMC-Magee Womens Hospital	Pittsburgh15213	NCT05564377	Map
PA	UPMC-Passavant Hospital	Pittsburgh15237	NCT05564377	Map
PA	Guthrie Medical Group PC-Robert Packer Hospital	Sayre18840	NCT05564377	Map
PA	Asplundh Cancer Pavilion	Willow Grove19090	NCT05564377	Map
PA	Lankenau Medical Center	Wynnewood19096	NCT05564377	Map
RI	Rhode Island Hospital	Providence02903	NCT04166409	Map
RI	Roger Williams Medical Center	Providence02908	NCT05564377	Map
RI	Women and Infants Hospital	Providence02905	NCT05564377	Map
SC	Prisma Health Cancer Institute - Spartanburg	Boiling Springs29316	NCT05564377	Map
SC	Medical University of South Carolina	Charleston29425	NCT04166409	Map
SC	Prisma Health Richland Hospital	Columbia29203	NCT04166409	Map
SC	Prisma Health Richland Hospital	Columbia29203	NCT05564377	Map
SC	Prisma Health Cancer Institute - Easley	Easley29640	NCT05564377	Map
SC	BI-LO Charities Children's Cancer Center	Greenville29605	NCT04166409	Map
SC	BI-LO Charities Children's Cancer Center	Greenville29605	NCT05564377	Map
SC	Prisma Health Cancer Institute - Butternut	Greenville29605	NCT05564377	Map
SC	Prisma Health Cancer Institute - Eastside	Greenville29615	NCT05564377	Map
SC	Prisma Health Cancer Institute - Faris	Greenville29605	NCT05564377	Map
SC	Saint Francis Cancer Center	Greenville29607	NCT05564377	Map
SC	Saint Francis Hospital	Greenville29601	NCT05564377	Map
SC	Prisma Health Cancer Institute - Greer	Greer29650	NCT05564377	Map
SC	Prisma Health Cancer Institute - Seneca	Seneca29672	NCT05564377	Map
SD	Rapid City Regional Hospital	Rapid City57701	NCT05564377	Map
SD	Sanford Cancer Center Oncology Clinic	Sioux Falls57104	NCT05564377	Map
SD	Sanford USD Medical Center - Sioux Falls	Sioux Falls57117-5134	NCT05564377	Map
TN	Baptist Memorial Hospital and Cancer Center-Collierville	Collierville38017	NCT05564377	Map
TN	Regional Cancer Center at Johnson City Medical Center	Johnson City37604	NCT05564377	Map
TN	Ballad Health Cancer Care - Kingsport	Kingsport37660	NCT05564377	Map
TN	East Tennessee Childrens Hospital	Knoxville37916	NCT04166409	Map
TN	Baptist Memorial Hospital and Cancer Center-Memphis	Memphis38120	NCT05564377	Map
TN	Saint Jude Children's Research Hospital	Memphis38105	NCT04166409	Map
TN	Vanderbilt Breast Center at One Hundred Oaks	Nashville37204	NCT05564377	Map
TN	Vanderbilt University/Ingram Cancer Center	Nashville37232	NCT04166409	Map
TN	Vanderbilt University/Ingram Cancer Center	Nashville37232	NCT05564377	Map
TX	Hendrick Medical Center	Abilene79601	NCT05564377	Map
TX	Dell Children's Medical Center of Central Texas	Austin78723	NCT04166409	Map
TX	University of Texas, Southwestern	Dallas75390	NCT06188741	Map
TX	University of Texas, Southwestern	Dallas75390	NCT06502171	Map
TX	UT Southwestern Medical Center	Dallas75235	NCT06735820	Map
TX	UT Southwestern/Simmons Cancer Center-Dallas	Dallas75390	NCT04166409	Map
TX	UT Southwestern/Simmons Cancer Center-Dallas	Dallas75390	NCT05564377	Map
TX	El Paso Children's Hospital	El Paso79905	NCT04166409	Map
TX	Cook Children's Medical Center	Fort Worth76104	NCT04166409	Map
TX	Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center	Houston77030	NCT04166409	Map
TX	Lyndon Baines Johnson General Hospital	Houston77026-1967	NCT05564377	Map
TX	UT MD Anderson Cancer Center	Houston77030	NCT04166409	Map
TX	UT MD Anderson Cancer Center	Houston77030	NCT05564377	Map
TX	Covenant Children's Hospital	Lubbock79410	NCT04166409	Map
TX	UMC Cancer Center / UMC Health System	Lubbock79415	NCT04166409	Map
TX	Children's Hospital of San Antonio	San Antonio78207	NCT04166409	Map
TX	Methodist Children's Hospital of South Texas	San Antonio78229	NCT04166409	Map
TX	University of Texas Health Science Center at San Antonio	San Antonio78229	NCT04166409	Map
TX	Scott and White Memorial Hospital	Temple76508	NCT05564377	Map
UT	Primary Children's Hospital	Salt Lake City84113	NCT04166409	Map
VT	University of Vermont and State Agricultural College	Burlington05405	NCT04166409	Map
VA	Ballad Health Cancer Care - Bristol	Bristol24201	NCT05564377	Map
VA	University of Virginia Cancer Center	Charlottesville22908	NCT05564377	Map
VA	Inova Schar Cancer Institute	Fairfax22031	NCT05564377	Map
VA	Inova Fairfax Hospital	Falls Church22042	NCT05564377	Map
VA	Children's Hospital of The King's Daughters	Norfolk23507	NCT04166409	Map
VA	Henrico Doctor's Hospital	Richmond23229	NCT05564377	Map
VA	VCU Massey Cancer Center at Stony Point	Richmond23235	NCT05564377	Map
VA	VCU Massey Comprehensive Cancer Center	Richmond23298	NCT04166409	Map
VA	VCU Massey Comprehensive Cancer Center	Richmond23298	NCT05564377	Map
VA	Carilion Children's	Roanoke24014	NCT04166409	Map
VA	Carilion Roanoke Memorial Hospital	Roanoke24033	NCT05564377	Map
VA	VCU Community Memorial Health Center	South Hill23970	NCT05564377	Map
WA	Swedish Cancer Institute-Edmonds	Edmonds98026	NCT05564377	Map
WA	Swedish Cancer Institute-Issaquah	Issaquah98029	NCT05564377	Map
WA	Providence Regional Cancer System-Lacey	Lacey98503	NCT05564377	Map
WA	Valley Medical Center	Renton98055	NCT05564377	Map
WA	Seattle Children's Hospital	Seattle98105	NCT04166409	Map
WA	Swedish Medical Center-First Hill	Seattle98122	NCT05564377	Map
WA	Providence Sacred Heart Medical Center and Children's Hospital	Spokane99204	NCT04166409	Map
WA	Madigan Army Medical Center	Tacoma98431	NCT04166409	Map
WA	Mary Bridge Children's Hospital and Health Center	Tacoma98405	NCT04166409	Map
WA	Providence Saint Mary Regional Cancer Center	Walla Walla99362	NCT05564377	Map
WA	North Star Lodge Cancer Center at Yakima Valley Memorial Hospital	Yakima98902	NCT05564377	Map
WV	West Virginia University Charleston Division	Charleston25304	NCT05564377	Map
WV	Edwards Comprehensive Cancer Center	Huntington25701	NCT05564377	Map
WV	West Virginia University Healthcare	Morgantown26506	NCT04166409	Map
WV	West Virginia University Healthcare	Morgantown26506	NCT05564377	Map
WI	ThedaCare Regional Cancer Center	Appleton54911	NCT05564377	Map
WI	ThedaCare Regional Medical Center - Appleton	Appleton54911	NCT05564377	Map
WI	Duluth Clinic Ashland	Ashland54806	NCT05564377	Map
WI	ThedaCare Cancer Care - Berlin	Berlin54923	NCT05564377	Map
WI	Aurora Cancer Care-Southern Lakes VLCC	Burlington53105	NCT05564377	Map
WI	Marshfield Medical Center-EC Cancer Center	Eau Claire54701	NCT05564377	Map
WI	Aurora Health Care Germantown Health Center	Germantown53022	NCT05564377	Map
WI	Aurora Cancer Care-Grafton	Grafton53024	NCT05564377	Map
WI	Aurora BayCare Medical Center	Green Bay54311	NCT05564377	Map
WI	Saint Vincent Hospital Cancer Center at Saint Mary's	Green Bay54303	NCT05564377	Map
WI	Saint Vincent Hospital Cancer Center Green Bay	Green Bay54301	NCT05564377	Map
WI	Mercyhealth Hospital and Cancer Center - Janesville	Janesville53548	NCT05564377	Map
WI	Aurora Cancer Care-Kenosha South	Kenosha53142	NCT05564377	Map
WI	Gundersen Lutheran Medical Center	La Crosse54601	NCT05564377	Map
WI	University of Wisconsin Carbone Cancer Center - Eastpark Medical Center	Madison53718	NCT05564377	Map
WI	University of Wisconsin Carbone Cancer Center - University Hospital	Madison53792	NCT04166409	Map
WI	University of Wisconsin Carbone Cancer Center - University Hospital	Madison53792	NCT05564377	Map
WI	Aurora Bay Area Medical Group-Marinette	Marinette54143	NCT05564377	Map
WI	Marshfield Medical Center-Marshfield	Marshfield54449	NCT05564377	Map
WI	Aurora Cancer Care-Milwaukee	Milwaukee53209	NCT05564377	Map
WI	Aurora Saint Luke's Medical Center	Milwaukee53215	NCT05564377	Map
WI	Aurora Sinai Medical Center	Milwaukee53233	NCT05564377	Map
WI	Children's Hospital of Wisconsin	Milwaukee53226	NCT04166409	Map
WI	Marshfield Medical Center - Minocqua	Minocqua54548	NCT05564377	Map
WI	ProHealth D N Greenwald Center	Mukwonago53149	NCT05564377	Map
WI	ThedaCare Regional Medical Center - Neenah	Neenah54956	NCT05564377	Map
WI	ThedaCare Cancer Care - New London	New London54961	NCT05564377	Map
WI	Cancer Center of Western Wisconsin	New Richmond54017	NCT05564377	Map
WI	ProHealth Oconomowoc Memorial Hospital	Oconomowoc53066	NCT05564377	Map
WI	Saint Vincent Hospital Cancer Center at Oconto Falls	Oconto Falls54154	NCT05564377	Map
WI	ThedaCare Cancer Care - Oshkosh	Oshkosh54904	NCT05564377	Map
WI	Vince Lombardi Cancer Clinic - Oshkosh	Oshkosh54904	NCT05564377	Map
WI	Aurora Cancer Care-Racine	Racine53406	NCT05564377	Map
WI	Marshfield Medical Center-Rice Lake	Rice Lake54868	NCT05564377	Map
WI	ThedaCare Cancer Care - Shawano	Shawano54166	NCT05564377	Map
WI	Saint Vincent Hospital Cancer Center at Sheboygan	Sheboygan53081	NCT05564377	Map
WI	Sheboygan Physicians Group	Sheboygan53081	NCT05564377	Map
WI	Vince Lombardi Cancer Clinic-Sheboygan	Sheboygan53081	NCT05564377	Map
WI	Marshfield Medical Center-River Region at Stevens Point	Stevens Point54482	NCT05564377	Map
WI	Saint Vincent Hospital Cancer Center at Sturgeon Bay	Sturgeon Bay54235-1495	NCT05564377	Map
WI	Aurora Medical Center in Summit	Summit53066	NCT05564377	—
WI	Vince Lombardi Cancer Clinic-Two Rivers	Two Rivers54241	NCT05564377	Map
WI	UW Cancer Center at ProHealth Care	Waukesha53188	NCT05564377	Map
WI	ThedaCare Cancer Care - Waupaca	Waupaca54981	NCT05564377	Map
WI	Aurora Cancer Care-Milwaukee West	Wauwatosa53226	NCT05564377	Map
WI	Aurora West Allis Medical Center	West Allis53227	NCT05564377	Map
WI	Marshfield Medical Center - Weston	Weston54476	NCT05564377	Map

Selumetinib clinical trials at a glance: phase × recruitment status

Phase	recruiting	active not recruiting	completed	terminated	withdrawn	not yet recruiting	unknown	approved for marketing	Total
P1	2	6	22	2					32
P1/P2	2	2	3	2			1		10
P2	3	8	25	5	4	3	1		49
P3	1	4	1	1					7
N/A								1	1

Recruiting Selumetinib clinical trials (11)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT ID	Title	Phase	Indication	Enrollment	Started
NCT06502171	NF113Study of Cabozantinib With Selumetinib for Plexiform Neurofibromas	P1	Neurofibromatosis 1	30	Jun 2026
NCT05253131	Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas	P2	MPNST	41	Aug 2026
NCT06188741	NF114Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1	P2	Neurofibromatosis 1	200	Aug 2025
NCT02813135	ESMARTEuropean Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors	P1/P2	Pediatric Cancer	472	Aug 2016
NCT04166409	A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma	P3	Low Grade Astrocytoma	170	Jan 2020
NCT05564377	Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial	P2	Advanced Malignant Solid Neoplasm	2,900	Apr 2023
NCT06763315	LS-NF1PNsLow-dose Selumetinib for the Treatment of Plexiform Neurofibromas in Chinese Children	P2	Plexiform Neurofibromas (PN)	50	Jan 2025
NCT06735820	MEKMDM2Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST	P1/P2	Malignant Peripheral Nerve Sheath Tumor (MPNST)	45	Jun 2026
NCT03326310	Selumetinib and Azacitidine in High Risk Chronic Blood Cancers	P1	Chronic Myeloid Leukemia	18	Sep 2018
NCT06620354	Clinical Study on the Treatment of Type I Neurofibromatosis With Smeitinib Hydrosulfate Capsule	P2	Neurofibromatosis 1	33	Sep 2024
NCT06621082	The Clinical Study of the Treatment of Patients With Type I Neurofibromatosis With Smetinib Hydrosulfate Capsule	P2	Neurofibromatosis 1	19	Sep 2024

Selumetinib clinical trials by indication

Neurofibromatosis 1 (6)

NCT	Acronym	Phase	Status	Title
NCT06502171	NF113	P1	recruiting	Study of Cabozantinib With Selumetinib for Plexiform Neurofibromas
NCT06188741	NF114	P2	recruiting	Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1
NCT04924608	KOMET	P3	active not recruiting	Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas
NCT06620354	—	P2	not yet recruiting	Clinical Study on the Treatment of Type I Neurofibromatosis With Smeitinib Hydrosulfate Capsule
NCT06621082	—	P2	not yet recruiting	The Clinical Study of the Treatment of Patients With Type I Neurofibromatosis With Smetinib Hydrosulfate Capsule
NCT04590235	NF1	P1	active not recruiting	A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)

Solid Tumours (6)

NCT	Acronym	Phase	Status	Title
NCT02056392	—	P1	completed	To Assess the Effects of Single Oral Dose of Selumetinib [AZD6244; ARRY-142886] [Hyd-Sulfate]), on QTc Interval in Healthy Male Volunteers
NCT02063204	—	P1	completed	To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Renal Impaired Subjects and Healthy Subjects
NCT02093728	—	P1	completed	To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers
NCT02046850	—	P1	completed	To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers
NCT01974349	—	P1	completed	To Assess the Effect of Food on the Pharmacokinetics of Selumetinib (AZD6244; ARRY-142886) (Hyd-Sulfate) in Healthy Male Volunteers
NCT01931761	ADME	P1	completed	Study Evaluating Absorption, Distribution, Metabolism and Excretion (ADME) of Single Dose [14C] Selumetinib in Volunteers

Neurofibromatosis Type 1 (5)

NCT	Acronym	Phase	Status	Title
NCT05309668	SPRINKLE	P1/P2	active not recruiting	Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN
NCT05101148	—	P1	active not recruiting	Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas
NCT05825365	PROTECT	P2	withdrawn	Selumetinib in Chinese Paediatric With Post-operative NF1-PNs, PhaseⅡ, Double-Blinded, Placebo-Controlled Study
NCT03326388	INSPECT	P1/P2	completed	Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours
NCT04495127	—	P1	completed	Selumetinib Paediatric NF1 Japan Study

Advanced Malignant Solid Neoplasm (3)

NCT	Acronym	Phase	Status	Title
NCT05564377	—	P2	recruiting	Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
NCT03155620	—	P2	active not recruiting	Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
NCT03213691	—	P2	completed	Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Non-Small Cell Lung Cancer (3)

NCT	Acronym	Phase	Status	Title
NCT03944772	ORCHARD	P2	active not recruiting	Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)
NCT02664935	—	P2	completed	National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer
NCT02337530	—	P2	completed	Selumetinib in Patients Receiving Pemetrexed and Platinum-based Chemotherapy in Advanced or Metastatic KRAS Wildtype or Unknown Non-Squamous NSCLC

Low Grade Glioma (2)

NCT	Acronym	Phase	Status	Title
NCT03871257	—	P3	active not recruiting	A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma
NCT01089101	—	P1/P2	active not recruiting	Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

Solid Tumors (2)

NCT	Acronym	Phase	Status	Title
NCT03745989	MK-8353-014	P1	completed	Study of MK-8353 + Selumetinib in Advanced/Metastatic Solid Tumors (MK-8353-014)
NCT02063230	—	P1	completed	To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects

Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IV (2)

NCT	Acronym	Phase	Status	Title
NCT01933932	SELECT-1	P3	active not recruiting	Assess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLC
NCT01750281	SELECT-2	P2	completed	Assess Efficacy and Safety of AZD6244 in Combination With Docetaxel in Patients Receiving Second Line Non Small Cell Lung Cancer Treatment.

Recurrent Melanoma (2)

NCT	Acronym	Phase	Status	Title
NCT00866177	—	P2	completed	MEK Inhibitor AZD6244 in Treating Patients With Stage III or Stage IV Melanoma
NCT01519427	—	P2	terminated	Selumetinib and Akt Inhibitor MK2206 in Treating Patients With Stage III or Stage IV Melanoma Who Failed Prior Therapy With Vemurafenib or Dabrafenib

Adult Solid Neoplasm (2)

NCT	Acronym	Phase	Status	Title
NCT00888134	—	P2	completed	Selumetinib in Cancers With BRAF Mutations
NCT01061749	—	P1	completed	Selumetinib and Cixutumumab in Treating Patients With Advanced Solid Malignancies

MPNST (1)

NCT	Acronym	Phase	Status	Title
NCT05253131	—	P2	recruiting	Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

Malignant Peripheral Nerve Sheath Tumor (MPNST) (1)

NCT	Acronym	Phase	Status	Title
NCT06735820	MEKMDM2	P1/P2	recruiting	Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST

Plexiform Neurofibromas (PN) (1)

NCT	Acronym	Phase	Status	Title
NCT06763315	LS-NF1PNs	P2	not yet recruiting	Low-dose Selumetinib for the Treatment of Plexiform Neurofibromas in Chinese Children

Recurrent Endometrial Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT05554328	—	P2	active not recruiting	Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

Recurrent Low Grade Astrocytoma (1)

NCT	Acronym	Phase	Status	Title
NCT04576117	—	P3	active not recruiting	A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

Metastatic Pancreatic Adenocarcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT04348045	MAZEPPA	P2	active not recruiting	Maintenance With Olaparib or Selumetinib + Durvaluma for m-PDAC Guided by BRCAness and KRAS Status.

Low Grade Astrocytoma (1)

NCT	Acronym	Phase	Status	Title
NCT04166409	—	P3	recruiting	A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Malignant Peripheral Nerve Sheath Tumors (1)

NCT	Acronym	Phase	Status	Title
NCT03433183	AZD6244	P2	completed	SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

Recurrent Lung Non-Small Cell Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT03581487	—	P1/P2	completed	Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer

Advanced/Metastatic Solid Tumors (1)

NCT	Acronym	Phase	Status	Title
NCT03833427	MK-5618	P1	terminated	Study of Selumetinib (MK-5618) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (MK-5618-001)

Anatomic Stage IV Breast Cancer AJCC v8 (1)

NCT	Acronym	Phase	Status	Title
NCT03801369	AMTEC IIT	P2	terminated	AMTEC IIT: Phase 2 Multiarm Study in TNBC

Chronic Myeloid Leukemia (1)

NCT	Acronym	Phase	Status	Title
NCT03326310	—	P1	recruiting	Selumetinib and Azacitidine in High Risk Chronic Blood Cancers

Malignant Neoplasm of Respiratory and Intrathoracic Organ Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT03004105	NSCLC	P2	withdrawn	MEDI4736 With Selumetinib for KRAS Mutant Non-Small Cell Lung Cancer (NSCLC)

Acute Lymphoblastic Leukemia (1)

NCT	Acronym	Phase	Status	Title
NCT03705507	SeluDex	P1/P2	terminated	International Trial of Selumetinib in Combination With Dexamethasone for the Treatment of Acute Lymphoblastic Leukaemia

Non-small Cell Lung Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT03392246	—	P2	active not recruiting	A Phase 2 Study of Osimertinib in Combination With Selumetinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer

Cutaneous Neurofibroma (1)

NCT	Acronym	Phase	Status	Title
NCT02839720	—	P2	completed	Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma

Malignant Neoplasm of Breast (1)

NCT	Acronym	Phase	Status	Title
NCT03162627	—	P1	active not recruiting	Selumetinib and Olaparib in Solid Tumors

KRAS NP_004976.2:p.G12R (1)

NCT	Acronym	Phase	Status	Title
NCT03040986	—	P2	completed	Selumetinib Sulfate in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer With KRAS G12R Mutations

Neurofibromatosis 2 (1)

NCT	Acronym	Phase	Status	Title
NCT03095248	SEL-TH-1601	P2	terminated	Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors

Neoplasms, Nerve Tissue (1)

NCT	Acronym	Phase	Status	Title
NCT03109301	NF1	P2	withdrawn	Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)

Uveal Melanoma (1)

NCT	Acronym	Phase	Status	Title
NCT02768766	—	P1	completed	Intermittent Selumetinib for Uveal Melanoma

Muscle Invasive Bladder Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT02546661	BISCAY	P1	active not recruiting	Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer

Triple Negative Breast Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT02685657	—	P2	unknown	Neoadjuvant Chemotherapy Docetaxel With or Without SELUMETINIB in Patients With Triple Negative Breast Cancer

Pediatric Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT02813135	ESMART	P1/P2	recruiting	European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors

Stage IIIB Non-Small Cell Lung Cancer AJCC v7 (1)

NCT	Acronym	Phase	Status	Title
NCT02503358	—	P1	completed	Selumetinib and Paclitaxel as Second-Line Treatment in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer

Neurofibromatosis 1 (NF1) (1)

NCT	Acronym	Phase	Status	Title
NCT02407405	NF1	P2	active not recruiting	MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

Lung Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT02586987	—	P1	completed	A Study to Assess the Safety, Tolerability and Anti-tumour Activity of Ascending Doses of Selumetinib in Combination With MEDI4736 and Selumetinib in Combination With MEDI4736 and Tremelimumab in Patients With Advanced Solid Tumours

Colorectal Neoplasms (1)

NCT	Acronym	Phase	Status	Title
NCT02450656	M14AFS	P1/P2	unknown	Afatinib and Selumetinib in Advanced KRAS Mutant and PIK3CA Wildtype Non-small Cell Lung Cancer

Metastatic Thyroid Gland Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT02393690	—	P2	completed	Iodine I-131 With or Without Selumetinib in Treating Patients With Recurrent or Metastatic Thyroid Cancer

Healthy Volunteers Bioequivalence or Bioavailability Study (1)

NCT	Acronym	Phase	Status	Title
NCT02322749	—	P1	completed	A Study to Assess the Relative Bioavailability of Process Variants of Selumetinib in Healthy Male Volunteers

Biliary Tract Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT02151084	—	P2	active not recruiting	A Study of Different Dosing Schedules of Selumetinib With Cisplatin/Gemcitabine (CIS/GEM) Versus CIS/GEM Alone in Biliary Cancer

Gastric Adenocarcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT02448290	—	P2	completed	Single-arm Study of Selumetinib in Combination With Docetaxel, in Advanced Gastric Adenocarcinoma Patients With Low/High MEK Signature, RAS Mutation or RAS Amplification as a Second-line Chemotherapy

Healthy Volunteers Bioavailability Study (1)

NCT	Acronym	Phase	Status	Title
NCT02238782	—	P1	completed	A Study to Assess the Absolute Bioavailability of Oral Selumetinib in Healthy Male Volunteers.

Non-small Cell Lung Cancer (NSCLC) (1)

NCT	Acronym	Phase	Status	Title
NCT02025114	—	P1/P2	completed	Selumetinib in Combination With Gefitinib in NSCLC Patients

Recurrent Colorectal Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT02188264	—	P1	completed	Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer

Advanced Non Small Cell Lung Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT02143466	—	P1	active not recruiting	AZD9291 in Combination With Ascending Doses of Novel Therapeutics

Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (Stage IIIB-IV) (1)

NCT	Acronym	Phase	Status	Title
NCT02179671	MEDI4736	P2	completed	Immune-Modulated Study of Selected Small Molecules (Gefitinib, AZD9291, or Selumetinib + Docetaxel) or a 1st Immune-Mediated Therapy (IMT; Tremelimumab) With a Sequential Switch to a 2nd IMT (MEDI4736) in Patients With Locally Advanced or Metastatic Non-Small-Cell Lung Cancer

Metastatic (1)

NCT	Acronym	Phase	Status	Title
NCT01974752	SUMIT	P3	completed	Selumetinib (AZD6244: ARRY-142886) (Hyd-Sulfate) in Metastatic Uveal Melanoma (SUMIT)

Non-small Cell Lung Cancer Metastatic (1)

NCT	Acronym	Phase	Status	Title
NCT02117167	SAFIR02_Lung	P2	completed	SAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC Patients

Metastatic Breast Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT02299999	SAFIR02_Breast	P2	active not recruiting	SAFIR02_Breast - Efficacy of Genome Analysis as a Therapeutic Decision Tool for Patients With Metastatic Breast Cancer

Healthy Volunteers Pharmacokinetic Study (1)

NCT	Acronym	Phase	Status	Title
NCT01960374	—	P1	completed	Dose-escalation Study to Assess Selumetinib Safety, Tolerability and PK

Inoperable Locally Advanced or Metastatic Biliary Tract Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT01949870	—	P1	terminated	Selumetinib (AZD6244, ARRY-142886) J-BTC Phase 1 Study

Differentiated Thyroid Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT01843062	ASTRA	P3	terminated	Comparing Complete Remission After Treatment With Selumetinib/Placebo in Patient With Differentiated Thyroid Cancer

Non Small Cell Lung Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT01783197	—	P1	completed	Study of Selumetinib in Patients With Previously Treated or Untreated Advanced/Metastatic NSCLC

Locally Advanced or Metastatic NSCL Cancer Stage IIIB IV (1)

NCT	Acronym	Phase	Status	Title
NCT01809210	SELECT-3	P1	completed	Assess Safety & Efficacy of Selumetinib When Given in Combination With Standard First Line Treatment for Advanced Non-small Cell Lung Cancer

Adenocarcinoma of the Gallbladder (1)

NCT	Acronym	Phase	Status	Title
NCT01859182	—	P2	withdrawn	Selumetinib and Akt Inhibitor MK-2206 in Treating Patients With Refractory or Advanced Gallbladder or Bile Duct Cancer That Cannot Be Removed By Surgery

Recurrent Colon Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT01217450	—	P1	completed	Selumetinib and Cetuximab in Treating Patients With Refractory Solid Tumors

Pancreatic Acinar Cell Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT01658943	S1115	P2	completed	Selumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With Chemotherapy

AIDS-related Kaposi's Sarcoma (1)

NCT	Acronym	Phase	Status	Title
NCT01752569	SCART	P1/P2	terminated	A Study of Selumetinib in Patients With Kaposi's Sarcoma

Biliary Tract Neoplasms (1)

NCT	Acronym	Phase	Status	Title
NCT01242605	ABC-04	P1	completed	ABC-04 a Study of Cisplatin, Gemcitabine and Selumetinib in Patients With Advanced Biliary Tract Cancer

Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT01586624	AZD6474	P1	completed	A Phase I Trial of Vandetanib (AZD6474) and Selumetinib (AZD6244) for Solid Tumours Including Non Small Cell Lung Cancer (VanSel-1)

Metastatic Melanoma (1)

NCT	Acronym	Phase	Status	Title
NCT01364051	—	P1	active not recruiting	Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies

Recurrent Adult Diffuse Large Cell Lymphoma (1)

NCT	Acronym	Phase	Status	Title
NCT01278615	—	P2	terminated	Selumetinib in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

Adenocarcinoma of the Pancreas (1)

NCT	Acronym	Phase	Status	Title
NCT01222689	—	P2	completed	Selumetinib and Erlotinib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

Mucosal Melanoma (1)

NCT	Acronym	Phase	Status	Title
NCT01166126	—	P2	terminated	Temsirolimus/AZD 6244 for Treatment-naive With BRAF Mutant Unresectable Stage IV

Recurrent Adult Soft Tissue Sarcoma (1)

NCT	Acronym	Phase	Status	Title
NCT01206140	—	P2	completed	Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery

Breast Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT01160718	—	P2	completed	Fulvestrant With or Without AZD6244 in Treating Patients With Advanced Breast Cancer That Progressed After Aromatase Inhibitor Therapy

Iris Melanoma (1)

NCT	Acronym	Phase	Status	Title
NCT01143402	—	P2	completed	Temozolomide or Selumetinib in Treating Patients With Metastatic Melanoma of the Eye

Recurrent Plasma Cell Myeloma (1)

NCT	Acronym	Phase	Status	Title
NCT01085214	—	P2	completed	AZD6244 (Selumetinib) in Treating Patients With Multiple Myeloma

Endometrial Adenocarcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT01011933	—	P2	completed	Selumetinib in Treating Patients With Recurrent or Persistent Endometrial Cancer

Recurrent Thyroid Gland Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT00559949	—	P2	completed	Selumetinib in Treating Patients With Papillary Thyroid Cancer That Did Not Respond to Radioactive Iodine

Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) (1)

NCT	Acronym	Phase	Status	Title
NCT00588809	—	P2	completed	Selumetinib in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia

Borderline Ovarian Serous Tumor (1)

NCT	Acronym	Phase	Status	Title
NCT00551070	—	P2	completed	Selumetinib Sulfate in Treating Woman With Recurrent Low-Grade Ovarian Cancer or Peritoneum Cancer

Liver and Intrahepatic Biliary Tract Cancer (1)

NCT	Acronym	Phase	Status	Title
NCT00553332	—	P2	completed	Selumetinib in Treating Patients With Biliary Cancer That Cannot Be Removed By Surgery

Adult Primary Hepatocellular Carcinoma (1)

NCT	Acronym	Phase	Status	Title
NCT00604721	—	P2	completed	Selumetinib in Treating Patients With Locally Advanced or Metastatic Liver Cancer

NF type1 With Inoperable Plexiform Neurofibromas (1)

NCT	Acronym	Phase	Status	Title
NCT03259633	—	N/A	approved for marketing	An Intermediate Access Protocol for Selumetinib for Treatment of Neurofibromatosis Type 1

Selumetinib pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

Acronym	NCT	Phase	Status	Indication	Enrollment	PubMed
KOMET	NCT04924608	P3	active not recruiting	Neurofibromatosis 1	145	PMID 40473450
SELECT-1	NCT01933932	P3	active not recruiting	Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IV	510	PMID 28492898
ASTRA	NCT01843062	P3	terminated	Differentiated Thyroid Cancer	233	PMID 35192411
SUMIT	NCT01974752	P3	completed	Metastatic	152	PMID 26059332
NF114	NCT06188741	P2	recruiting	Neurofibromatosis 1	200	—
NF1	NCT02407405	P2	active not recruiting	Neurofibromatosis 1 (NF1)	36	PMID 33536190
LS-NF1PNs	NCT06763315	P2	not yet recruiting	Plexiform Neurofibromas (PN)	50	PMID 35579709
PROTECT	NCT05825365	P2	withdrawn	Neurofibromatosis Type 1	0	—
MAZEPPA	NCT04348045	P2	active not recruiting	Metastatic Pancreatic Adenocarcinoma	307	—
SAFIR02_Breast	NCT02299999	P2	active not recruiting	Metastatic Breast Cancer	1,460	PMID 32067679
ORCHARD	NCT03944772	P2	active not recruiting	Non-Small Cell Lung Cancer	247	PMID 34389237
AMTEC IIT	NCT03801369	P2	terminated	Anatomic Stage IV Breast Cancer AJCC v8	24	PMID 32379297
NSCLC	NCT03004105	P2	withdrawn	Malignant Neoplasm of Respiratory and Intrathoracic Organ Carcinoma	0	—
SEL-TH-1601	NCT03095248	P2	terminated	Neurofibromatosis 2	10	—
SAFIR02_Lung	NCT02117167	P2	completed	Non-small Cell Lung Cancer Metastatic	999	PMID 26410619
AZD6244	NCT03433183	P2	completed	Malignant Peripheral Nerve Sheath Tumors	21	—
SELECT-2	NCT01750281	P2	completed	Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IV	212	PMID 29045535
NF1	NCT03109301	P2	withdrawn	Neoplasms, Nerve Tissue	0	—
MEDI4736	NCT02179671	P2	completed	Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (Stage IIIB-IV)	32	—
S1115	NCT01658943	P2	completed	Pancreatic Acinar Cell Carcinoma	137	PMID 27978579

Terminated and withdrawn Selumetinib trials (14)

Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.

NCT05825365withdrawnSelumetinib in Chinese Paediatric With Post-operative NF1-PNs, PhaseⅡ, Double-Blinded, Placebo-Controlled Study
NCT03801369terminatedAMTEC IIT: Phase 2 Multiarm Study in TNBC
NCT03004105withdrawnMEDI4736 With Selumetinib for KRAS Mutant Non-Small Cell Lung Cancer (NSCLC)
NCT03095248terminatedTrial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors
NCT03705507terminatedInternational Trial of Selumetinib in Combination With Dexamethasone for the Treatment of Acute Lymphoblastic Leukaemia
NCT03833427terminatedStudy of Selumetinib (MK-5618) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (MK-5618-001)
NCT03109301withdrawnMitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)
NCT01843062terminatedComparing Complete Remission After Treatment With Selumetinib/Placebo in Patient With Differentiated Thyroid Cancer
NCT01752569terminatedA Study of Selumetinib in Patients With Kaposi's Sarcoma
NCT01949870terminatedSelumetinib (AZD6244, ARRY-142886) J-BTC Phase 1 Study
NCT01278615terminatedSelumetinib in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma
NCT01859182withdrawnSelumetinib and Akt Inhibitor MK-2206 in Treating Patients With Refractory or Advanced Gallbladder or Bile Duct Cancer That Cannot Be Removed By Surgery
NCT01519427terminatedSelumetinib and Akt Inhibitor MK2206 in Treating Patients With Stage III or Stage IV Melanoma Who Failed Prior Therapy With Vemurafenib or Dabrafenib
NCT01166126terminatedTemsirolimus/AZD 6244 for Treatment-naive With BRAF Mutant Unresectable Stage IV

All Selumetinib trials (99)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT ID	Acronym	Title	Phase	Status	Enrollment	Sponsor	Started
NCT06502171	NF113	Study of Cabozantinib With Selumetinib for Plexiform Neurofibromas	P1	recruiting	30	Girish Dhall, MD	Jun 2026
NCT05253131		Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas	P2	recruiting	41	University of Alabama at Birmingham	Aug 2026
NCT06188741	NF114	Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1	P2	recruiting	200	University of Alabama at Birmingham	Aug 2025
NCT02813135	ESMART	European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors	P1/P2	recruiting	472	Gustave Roussy, Cancer Campus, Grand Paris	Aug 2016
NCT04166409		A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma	P3	recruiting	170	National Cancer Institute (NCI)	Jan 2020
NCT05564377		Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial	P2	recruiting	2,900	National Cancer Institute (NCI)	Apr 2023
NCT02407405	NF1	MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas	P2	active not recruiting	36	National Cancer Institute (NCI)	Jan 2016
NCT04924608	KOMET	Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas	P3	active not recruiting	145	AstraZeneca	Nov 2021
NCT06763315	LS-NF1PNs	Low-dose Selumetinib for the Treatment of Plexiform Neurofibromas in Chinese Children	P2	not yet recruiting	50	West China Hospital	Jan 2025
NCT06735820	MEKMDM2	Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST	P1/P2	recruiting	45	AeRang Kim	Jun 2026
NCT05554328		Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial	P2	active not recruiting	165	National Cancer Institute (NCI)	Apr 2023
NCT05309668	SPRINKLE	Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN	P1/P2	active not recruiting	36	AstraZeneca	Jan 2022
NCT05101148		Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas	P1	active not recruiting	24	AstraZeneca	Jul 2021
NCT03871257		A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma	P3	active not recruiting	165	National Cancer Institute (NCI)	Jan 2020
NCT03392246		A Phase 2 Study of Osimertinib in Combination With Selumetinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer	P2	active not recruiting	25	Dana-Farber Cancer Institute	Jan 2018
NCT02151084		A Study of Different Dosing Schedules of Selumetinib With Cisplatin/Gemcitabine (CIS/GEM) Versus CIS/GEM Alone in Biliary Cancer	P2	active not recruiting	57	University Health Network, Toronto	Nov 2014
NCT03326310		Selumetinib and Azacitidine in High Risk Chronic Blood Cancers	P1	recruiting	18	University of Chicago	Sep 2018
NCT01364051		Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies	P1	active not recruiting	19	National Cancer Institute (NCI)	May 2011
NCT01089101		Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma	P1/P2	active not recruiting	217	National Cancer Institute (NCI)	Jul 2010
NCT03155620		Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)	P2	active not recruiting	1,377	National Cancer Institute (NCI)	Jul 2017
NCT06620354		Clinical Study on the Treatment of Type I Neurofibromatosis With Smeitinib Hydrosulfate Capsule	P2	not yet recruiting	33	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Sep 2024
NCT06621082		The Clinical Study of the Treatment of Patients With Type I Neurofibromatosis With Smetinib Hydrosulfate Capsule	P2	not yet recruiting	19	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Sep 2024
NCT02143466		AZD9291 in Combination With Ascending Doses of Novel Therapeutics	P1	active not recruiting	344	AstraZeneca	Aug 2014
NCT01933932	SELECT-1	Assess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLC	P3	active not recruiting	510	AstraZeneca	Sep 2013
NCT04576117		A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma	P3	active not recruiting	300	National Cancer Institute (NCI)	Feb 2021
NCT04590235	NF1	A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)	P1	active not recruiting	32	AstraZeneca	Dec 2020
NCT03162627		Selumetinib and Olaparib in Solid Tumors	P1	active not recruiting	90	M.D. Anderson Cancer Center	Aug 2017
NCT05825365	PROTECT	Selumetinib in Chinese Paediatric With Post-operative NF1-PNs, PhaseⅡ, Double-Blinded, Placebo-Controlled Study	P2	withdrawn	0	AstraZeneca	Aug 2023
NCT02546661	BISCAY	Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer	P1	active not recruiting	117	AstraZeneca	Dec 2016
NCT04348045	MAZEPPA	Maintenance With Olaparib or Selumetinib + Durvaluma for m-PDAC Guided by BRCAness and KRAS Status.	P2	active not recruiting	307	GERCOR - Multidisciplinary Oncology Cooperative Group	Dec 2020
NCT02299999	SAFIR02_Breast	SAFIR02_Breast - Efficacy of Genome Analysis as a Therapeutic Decision Tool for Patients With Metastatic Breast Cancer	P2	active not recruiting	1,460	UNICANCER	Apr 2014
NCT03581487		Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer	P1/P2	completed	40	M.D. Anderson Cancer Center	Apr 2019
NCT03944772	ORCHARD	Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)	P2	active not recruiting	247	AstraZeneca	Jun 2019
NCT03213691		Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)	P2	completed	21	National Cancer Institute (NCI)	Oct 2017
NCT03801369	AMTEC IIT	AMTEC IIT: Phase 2 Multiarm Study in TNBC	P2	terminated	24	Gordon Mills, MD, PhD	Dec 2018
NCT03004105	NSCLC	MEDI4736 With Selumetinib for KRAS Mutant Non-Small Cell Lung Cancer (NSCLC)	P2	withdrawn	0	M.D. Anderson Cancer Center	May 2018
NCT03095248	SEL-TH-1601	Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors	P2	terminated	10	Children's Hospital Medical Center, Cincinnati	May 2017
NCT03326388	INSPECT	Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours	P1/P2	completed	14	Great Ormond Street Hospital for Children NHS Foundation Trust	Sep 2019
NCT02393690		Iodine I-131 With or Without Selumetinib in Treating Patients With Recurrent or Metastatic Thyroid Cancer	P2	completed	60	Academic and Community Cancer Research United	May 2015
NCT02117167	SAFIR02_Lung	SAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC Patients	P2	completed	999	UNICANCER	Apr 2014
NCT02664935		National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer	P2	completed	423	University of Birmingham	May 2015
NCT03433183	AZD6244	SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors	P2	completed	21	Sarcoma Alliance for Research through Collaboration	Oct 2019
NCT02839720		Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma	P2	completed	11	National Cancer Institute (NCI)	Aug 2017
NCT03705507	SeluDex	International Trial of Selumetinib in Combination With Dexamethasone for the Treatment of Acute Lymphoblastic Leukaemia	P1/P2	terminated	12	University of Birmingham	May 2018
NCT04495127		Selumetinib Paediatric NF1 Japan Study	P1	completed	12	AstraZeneca	Aug 2020
NCT01750281	SELECT-2	Assess Efficacy and Safety of AZD6244 in Combination With Docetaxel in Patients Receiving Second Line Non Small Cell Lung Cancer Treatment.	P2	completed	212	AstraZeneca	Dec 2012
NCT03833427	MK-5618	Study of Selumetinib (MK-5618) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (MK-5618-001)	P1	terminated	32	Merck Sharp & Dohme LLC	Mar 2019
NCT03745989	MK-8353-014	Study of MK-8353 + Selumetinib in Advanced/Metastatic Solid Tumors (MK-8353-014)	P1	completed	30	Merck Sharp & Dohme LLC	Feb 2019
NCT00551070		Selumetinib Sulfate in Treating Woman With Recurrent Low-Grade Ovarian Cancer or Peritoneum Cancer	P2	completed	52	National Cancer Institute (NCI)	Dec 2007
NCT03040986		Selumetinib Sulfate in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer With KRAS G12R Mutations	P2	completed	8	National Cancer Institute (NCI)	Jul 2017
NCT02768766		Intermittent Selumetinib for Uveal Melanoma	P1	completed	42	Shaheer A. Khan	Feb 2017
NCT02503358		Selumetinib and Paclitaxel as Second-Line Treatment in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer	P1	completed	23	OHSU Knight Cancer Institute	Jul 2016
NCT01586624	AZD6474	A Phase I Trial of Vandetanib (AZD6474) and Selumetinib (AZD6244) for Solid Tumours Including Non Small Cell Lung Cancer (VanSel-1)	P1	completed	61	Cancer Research UK	Jan 2012
NCT02450656	M14AFS	Afatinib and Selumetinib in Advanced KRAS Mutant and PIK3CA Wildtype Non-small Cell Lung Cancer	P1/P2	unknown	320	The Netherlands Cancer Institute	Jun 2015
NCT02586987		A Study to Assess the Safety, Tolerability and Anti-tumour Activity of Ascending Doses of Selumetinib in Combination With MEDI4736 and Selumetinib in Combination With MEDI4736 and Tremelimumab in Patients With Advanced Solid Tumours	P1	completed	58	AstraZeneca	Dec 2015
NCT02337530		Selumetinib in Patients Receiving Pemetrexed and Platinum-based Chemotherapy in Advanced or Metastatic KRAS Wildtype or Unknown Non-Squamous NSCLC	P2	completed	62	Canadian Cancer Trials Group	May 2015
NCT02188264		Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer	P1	completed	40	National Cancer Institute (NCI)	Aug 2014
NCT01783197		Study of Selumetinib in Patients With Previously Treated or Untreated Advanced/Metastatic NSCLC	P1	completed	39	Canadian Cancer Trials Group	Jun 2013
NCT03109301	NF1	Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)	P2	withdrawn	0	National Cancer Institute (NCI)	Apr 2017
NCT01843062	ASTRA	Comparing Complete Remission After Treatment With Selumetinib/Placebo in Patient With Differentiated Thyroid Cancer	P3	terminated	233	AstraZeneca	Aug 2013
NCT02448290		Single-arm Study of Selumetinib in Combination With Docetaxel, in Advanced Gastric Adenocarcinoma Patients With Low/High MEK Signature, RAS Mutation or RAS Amplification as a Second-line Chemotherapy	P2	completed	25	Samsung Medical Center	Nov 2014
NCT02025114		Selumetinib in Combination With Gefitinib in NSCLC Patients	P1/P2	completed	34	National Taiwan University Hospital	Sep 2014
NCT01752569	SCART	A Study of Selumetinib in Patients With Kaposi's Sarcoma	P1/P2	terminated	19	Sheffield Teaching Hospitals NHS Foundation Trust	Jun 2012
NCT03259633		An Intermediate Access Protocol for Selumetinib for Treatment of Neurofibromatosis Type 1	—	approved for marketing	0	AstraZeneca	—
NCT01974752	SUMIT	Selumetinib (AZD6244: ARRY-142886) (Hyd-Sulfate) in Metastatic Uveal Melanoma (SUMIT)	P3	completed	152	AstraZeneca	Apr 2014
NCT02685657		Neoadjuvant Chemotherapy Docetaxel With or Without SELUMETINIB in Patients With Triple Negative Breast Cancer	P2	unknown	164	Russian Academy of Medical Sciences	Sep 2016
NCT01160718		Fulvestrant With or Without AZD6244 in Treating Patients With Advanced Breast Cancer That Progressed After Aromatase Inhibitor Therapy	P2	completed	46	Swiss Cancer Institute	Aug 2010
NCT00559949		Selumetinib in Treating Patients With Papillary Thyroid Cancer That Did Not Respond to Radioactive Iodine	P2	completed	39	National Cancer Institute (NCI)	Dec 2007
NCT02179671	MEDI4736	Immune-Modulated Study of Selected Small Molecules (Gefitinib, AZD9291, or Selumetinib + Docetaxel) or a 1st Immune-Mediated Therapy (IMT; Tremelimumab) With a Sequential Switch to a 2nd IMT (MEDI4736) in Patients With Locally Advanced or Metastatic Non-Small-Cell Lung Cancer	P2	completed	32	AstraZeneca	Jul 2014
NCT01242605	ABC-04	ABC-04 a Study of Cisplatin, Gemcitabine and Selumetinib in Patients With Advanced Biliary Tract Cancer	P1	completed	13	University College, London	Feb 2012
NCT01143402		Temozolomide or Selumetinib in Treating Patients With Metastatic Melanoma of the Eye	P2	completed	120	National Cancer Institute (NCI)	Jun 2010
NCT01011933		Selumetinib in Treating Patients With Recurrent or Persistent Endometrial Cancer	P2	completed	54	National Cancer Institute (NCI)	Sep 2009
NCT01809210	SELECT-3	Assess Safety & Efficacy of Selumetinib When Given in Combination With Standard First Line Treatment for Advanced Non-small Cell Lung Cancer	P1	completed	55	AstraZeneca	Apr 2013
NCT01658943	S1115	Selumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With Chemotherapy	P2	completed	137	National Cancer Institute (NCI)	Aug 2012
NCT02322749		A Study to Assess the Relative Bioavailability of Process Variants of Selumetinib in Healthy Male Volunteers	P1	completed	48	AstraZeneca	Feb 2015
NCT01206140		Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery	P2	completed	70	National Cancer Institute (NCI)	Oct 2010
NCT00888134		Selumetinib in Cancers With BRAF Mutations	P2	completed	28	National Cancer Institute (NCI)	Jul 2009
NCT02238782		A Study to Assess the Absolute Bioavailability of Oral Selumetinib in Healthy Male Volunteers.	P1	completed	21	AstraZeneca	Oct 2014
NCT02063230		To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects	P1	completed	32	AstraZeneca	Mar 2014
NCT01222689		Selumetinib and Erlotinib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer	P2	completed	46	National Cancer Institute (NCI)	Nov 2010
NCT01061749		Selumetinib and Cixutumumab in Treating Patients With Advanced Solid Malignancies	P1	completed	30	National Cancer Institute (NCI)	Nov 2009
NCT02056392		To Assess the Effects of Single Oral Dose of Selumetinib [AZD6244; ARRY-142886] [Hyd-Sulfate]), on QTc Interval in Healthy Male Volunteers	P1	completed	54	AstraZeneca	Mar 2014
NCT01949870		Selumetinib (AZD6244, ARRY-142886) J-BTC Phase 1 Study	P1	terminated	6	AstraZeneca	Oct 2013
NCT02063204		To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Renal Impaired Subjects and Healthy Subjects	P1	completed	24	AstraZeneca	Mar 2014
NCT02093728		To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers	P1	completed	26	AstraZeneca	Apr 2014
NCT01960374		Dose-escalation Study to Assess Selumetinib Safety, Tolerability and PK	P1	completed	117	AstraZeneca	Oct 2013
NCT01217450		Selumetinib and Cetuximab in Treating Patients With Refractory Solid Tumors	P1	completed	33	National Cancer Institute (NCI)	Oct 2012
NCT01278615		Selumetinib in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma	P2	terminated	16	National Cancer Institute (NCI)	Dec 2010
NCT02046850		To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers	P1	completed	24	AstraZeneca	Feb 2014
NCT01974349		To Assess the Effect of Food on the Pharmacokinetics of Selumetinib (AZD6244; ARRY-142886) (Hyd-Sulfate) in Healthy Male Volunteers	P1	completed	39	AstraZeneca	Nov 2013
NCT01931761	ADME	Study Evaluating Absorption, Distribution, Metabolism and Excretion (ADME) of Single Dose [14C] Selumetinib in Volunteers	P1	completed	6	AstraZeneca	Oct 2013
NCT00866177		MEK Inhibitor AZD6244 in Treating Patients With Stage III or Stage IV Melanoma	P2	completed	167	National Cancer Institute (NCI)	Mar 2009
NCT01859182		Selumetinib and Akt Inhibitor MK-2206 in Treating Patients With Refractory or Advanced Gallbladder or Bile Duct Cancer That Cannot Be Removed By Surgery	P2	withdrawn	0	National Cancer Institute (NCI)	Jan 2013
NCT01519427		Selumetinib and Akt Inhibitor MK2206 in Treating Patients With Stage III or Stage IV Melanoma Who Failed Prior Therapy With Vemurafenib or Dabrafenib	P2	terminated	2	National Cancer Institute (NCI)	Jan 2012
NCT00553332		Selumetinib in Treating Patients With Biliary Cancer That Cannot Be Removed By Surgery	P2	completed	29	National Cancer Institute (NCI)	Nov 2007
NCT00588809		Selumetinib in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia	P2	completed	47	National Cancer Institute (NCI)	Dec 2007
NCT01166126		Temsirolimus/AZD 6244 for Treatment-naive With BRAF Mutant Unresectable Stage IV	P2	terminated	4	National Cancer Institute (NCI)	Oct 2010
NCT00604721		Selumetinib in Treating Patients With Locally Advanced or Metastatic Liver Cancer	P2	completed	19	National Cancer Institute (NCI)	Nov 2007
NCT01085214		AZD6244 (Selumetinib) in Treating Patients With Multiple Myeloma	P2	completed	37	National Cancer Institute (NCI)	Mar 2010

Selumetinib clinical trials: frequently asked questions

How many Selumetinib clinical trials are there?: 99 Selumetinib clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 8 are actively recruiting participants. 51 are marked completed.
Are Selumetinib clinical trials recruiting in 2026?: Yes — 8 Selumetinib trials are actively recruiting in 2026, with 573 U.S. sites across 48 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Selumetinib being studied for?: Selumetinib is being studied for Neurofibromatosis 1, Neurofibromatosis Type 1, Solid Tumours, Low Grade Glioma, Recurrent Malignant Solid Neoplasm and 263 more. The trials are grouped by indication on this page.
What phase is Selumetinib in?: Selumetinib clinical trials span 7 Phase 3, 49 Phase 2, 32 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Selumetinib clinical trials?: The lead sponsor across the most Selumetinib trials is National Cancer Institute (NCI), with 31 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Selumetinibas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed September 1, 2026.

Related pages on Hipa.ai:

Selumetinib overview Selumetinib evidence & publications