Cleveland Clinic, Cole Eye Institute

Clinical research site in Cleveland, Ohio · Cleveland Clinic-Cole Eye Institute, 9500 Euclid Ave # S40, Cleveland, OH 44195 · (216) 444-2020 · Website

Part of Cleveland Clinic

As of July 2026, 10 paid clinical trials are recruiting at Cleveland Clinic, Cole Eye Institute in Cleveland, Ohio. Active studies at this site cover conditions such as Uveal Melanoma, Choroidal Melanoma and Indeterminate Lesions. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

Recruiting clinical trials at Cleveland Clinic, Cole Eye Institute (10)

Neoadjuvant Darovasertib in Primary Uveal Melanoma

for Uveal Melanoma

35 locations incl. Scottsdale

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT07015190·Phase 3·Recruiting·Listed Jun 2025

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A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

for Choroidal Melanoma

34 locations incl. La Jolla

Sponsor: Aura Biosciences

Sex: All·Age: 18+

Code: NCT06007690·Phase 3·Recruiting·Listed Aug 2023

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Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

for Neurotrophic Keratopathy

24 locations incl. Laguna Hills

Sponsor: ReGenTree, LLC

Sex: All·Age: 18+

Code: NCT05555589·Phase 3·Recruiting·Listed Sep 2022

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Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma

for Open Angle Glaucoma (OAG)

9 locations incl. Glendale

Sponsor: Avisi Technologies Inc.

Sex: All·Age: 45+

Code: NCT07220876·Recruiting·Listed Oct 2025

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Suprachoroidal Administration in Subjects With Metastases to the Choroid

for Eye Cancer

10 locations incl. Palo Alto

Sponsor: Aura Biosciences

Sex: All·Age: 18+

Code: NCT06643884·Phase 2·Recruiting·Listed Oct 2024

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Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD

for Age-Related Macular Degeneration

10 locations incl. Loma Linda

Sponsor: VisionCare, Inc.

Sex: All·Age: 65+

Code: NCT05438732·Recruiting·Listed Jun 2022

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Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

73 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting·Listed Apr 2024

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Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age

for Amblyopia

58 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 8 - 12

Code: NCT06524882·Phase 3·Recruiting·Listed Jul 2024

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Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography

for Uveitis

1 location in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01746537·Recruiting·Listed Dec 2012

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Clarifying the Optimal Application of SLT Therapy Trial

for Glaucoma and Ocular Hypertension

27 locations incl. Laguna Hills

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04967989·Phase 3·Recruiting·Listed Jul 2021

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Paid clinical trials in Cleveland, OH · Ohio clinical trials