A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
for Macular Degeneration
61 locations incl. Scottsdale
Sponsor: EyeBiotech Ltd.
Sex: All·Age: 50+
Code: NCT07440225·Phase 2, Phase 3·Recruiting·Listed Feb 2026
Springfield Clinic - First
Clinical research site in Springfield, Illinois · 1025 S 6TH ST, SPRINGFIELD, IL 62703-2403 · (217) 528-7541
As of September 2026, 103 paid clinical trials are recruiting at Springfield Clinic - First in Springfield, Illinois. Active studies at this site cover conditions such as Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia and Anatomic Stage II Breast Cancer AJCC v8. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Recruiting clinical trials at Springfield Clinic - First (103)
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
for Ulcerative Colitis (UC)
50 locations incl. Phoenix
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 80
Code: NCT07415044·Phase 2·Recruiting·Listed Feb 2026
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
for CRC (Colorectal Cancer)
71 locations incl. Mobile
Sponsor: Incyte Corporation
Sex: All·Age: 18+
Code: NCT07284849·Phase 3·Recruiting·Listed Dec 2025
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
for Heart Failure
86 locations incl. Covina
Sponsor: Boehringer Ingelheim
Sex: All·Age: 18+
Code: NCT06935370·Phase 3·Recruiting·Listed Apr 2025
A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
for Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer
47 locations incl. Daphne
Sponsor: Hoffmann-La Roche
Sex: All·Age: 18+
Code: NCT06065748·Phase 3·Recruiting·Listed Oct 2023
A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting
for Ulcerative Colitis
77 locations incl. Birmingham
Sponsor: Takeda
Sex: All·Age: 18 - 80
Code: NCT06581328·Phase 4·Recruiting·Listed Sep 2024
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
for Non-Small Cell Lung Cancer
37 locations incl. Chandler
Sponsor: AbbVie
Sex: All·Age: 18+
Code: NCT06568939·Phase 2·Recruiting·Listed Aug 2024
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
for Breast Cancer
59 locations incl. Goodyear
Sponsor: Hoffmann-La Roche
Sex: All·Age: 18+
Code: NCT06790693·Phase 3·Recruiting·Listed Jan 2025
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
for Carcinoma, Non-Small Cell Lung
104 locations incl. Anchorage
Sponsor: Seagen, a wholly owned subsidiary of Pfizer
Sex: All·Age: 18+
Code: NCT04389632·Phase 1·Recruiting·Listed May 2020
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
for Neovascular Age-Related Macular Degeneration (nAMD)
54 locations incl. Scottsdale
Sponsor: 4D Molecular Therapeutics
Sex: All·Age: 50+
Code: NCT07064759·Phase 3·Recruiting·Listed Jul 2025
A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)
for Chronic Lymphocytic Leukemia
31 locations incl. Tucson
Sponsor: AbbVie
Sex: All·Age: 18+
Code: NCT06428019·Phase 3·Recruiting·Listed May 2024
Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening
for Lung Cancer Diagnosis
36 locations incl. Los Angeles
Sponsor: Freenome Holdings Inc.
Sex: All·Age: 50+
Code: NCT06122077·Recruiting·Listed Nov 2023
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)
for Irritable Bowel Syndrome
14 locations incl. Mesa
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 75
Code: NCT07545772·Phase 2·Recruiting·Listed Apr 2026
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)
for Irritable Bowel Syndrome
15 locations incl. Mesa
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 75
Code: NCT07545759·Phase 2·Recruiting·Listed Apr 2026
Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer
for Extensive Stage Small Cell Lung Cancer (ES-SCLC)
23 locations incl. Anchorage
Sponsor: Gilead Sciences
Sex: All·Age: 18+
Code: NCT06801834·Phase 3·Recruiting·Listed Jan 2025
Collection of Samples USOPTIVAL Study
for Colorectal Cancer (CRC)
4 locations incl. Lakeland
Sponsor: Universal Diagnostics
Sex: All·Age: 45 - 84·Accepts healthy volunteers
Code: NCT04792684·Recruiting·Listed Mar 2021
A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
for Metastatic Colorectal Cancer
18 locations incl. Lone Tree
Sponsor: EMD Serono Research & Development Institute, Inc.
Sex: All·Age: 18+
Code: NCT07549412·Phase 3·Recruiting·Listed Apr 2026
A Study to Evaluate the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia
for Patients With Chemotherapy-Induced Thrombocytopenia
7 locations incl. Los Alamitos
Sponsor: Jiangsu HengRui Medicine Co., Ltd.
Sex: All·Age: 18+
Code: NCT07286032·Phase 3·Recruiting·Listed Dec 2025
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial
for Anatomic Stage II Breast Cancer AJCC v8
143 locations incl. Jonesboro
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT07391774·Phase 3·Recruiting·Listed Feb 2026
Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial
for Lung Non-Small Cell Carcinoma
59 locations incl. Beverly Hills
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT07388524·Phase 3·Recruiting·Listed Feb 2026
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL
for Chronic Lymphocytic Leukemia
181 locations incl. Los Angeles
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 65+
Code: NCT07321652·Phase 3·Recruiting·Listed Jan 2026
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
for Ampulla of Vater Carcinoma
349 locations incl. Fairbanks
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07283939·Recruiting·Listed Dec 2025
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
for Advanced Endometrial Carcinoma
256 locations incl. Birmingham
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 18+
Code: NCT07198074·Phase 3·Recruiting·Listed Sep 2025
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
for Lung Non-Small Cell Carcinoma
623 locations incl. Anchorage
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
1100 locations incl. Anchorage
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Family Communications After Genetic Testing
for Colon Adenocarcinoma
290 locations incl. Anchorage
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07143487·Recruiting·Listed Aug 2025
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
915 locations incl. Fairhope
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
for Head and Neck Squamous Cell Carcinoma
463 locations incl. Anchorage
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT02734537·Phase 2·Recruiting·Listed Apr 2016
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
779 locations incl. Issaquah
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
for Intracranial Meningioma
446 locations incl. Anchorage
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT02523014·Phase 2·Recruiting·Listed Aug 2015
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
for Advanced Esophageal Adenocarcinoma
632 locations incl. Anchorage
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05677490·Phase 3·Recruiting·Listed Jan 2023
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
for Plasma Cell Myeloma
305 locations incl. Alpena
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT04566328·Phase 3·Recruiting·Listed Sep 2020
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for Anatomic Stage I Breast Cancer AJCC v8
593 locations incl. Phoenix
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025
Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers
for Metastatic Small Intestinal Adenocarcinoma
399 locations incl. Anchorage
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT04205968·Phase 2·Recruiting·Listed Dec 2019
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
for Acute Lymphoblastic Leukemia
618 locations incl. Anchorage
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 40 - 75·Accepts healthy volunteers
Code: NCT05334069·Recruiting·Listed Apr 2022
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
484 locations incl. Birmingham
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
for Chronic Lymphocytic Leukemia
297 locations incl. Tucson
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
for Bladder Adenocarcinoma
222 locations incl. Phoenix
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT03866382·Phase 2·Recruiting·Listed Mar 2019
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
for Advanced Lung Non-Squamous Non-Small Cell Carcinoma
327 locations incl. Anchorage
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04181060·Phase 3·Recruiting·Listed Nov 2019
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer
for Miscellaneous Neoplasm, Nos
278 locations incl. Anchorage
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07091617·Recruiting·Listed Jul 2025
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Paid clinical trials in Springfield, IL · Illinois clinical trials