St.Jude Children's Research Hospital

Clinical research site in Memphis, Tennessee · 262 DANNY THOMAS PL, MEMPHIS, TN 38105-3678 · (901) 595-2911

As of September 2026, 128 paid clinical trials are recruiting at St.Jude Children's Research Hospital in Memphis, Tennessee. Active studies at this site cover conditions such as Sickle Cell Disease, Hematologic Malignancy and Pediatric Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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Recruiting clinical trials at St.Jude Children's Research Hospital (128)

A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT

for Adenovirus Infections

32 locations incl. Phoenix

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT07387367·Phase 3·Recruiting·Listed Feb 2026

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A Long-term Follow-up Study in Patients Who Received BEAM-101

for Hemoglobinopathy

17 locations incl. Birmingham

Sponsor: Beam Therapeutics Inc.

Sex: All·Age: 14 - 37

Code: NCT07373639·Recruiting·Listed Jan 2026

Apply to this trial

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

for Refractory Ewing Sarcoma

14 locations incl. Los Angeles

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 2 - 30

Code: NCT05734066·Phase 1, Phase 2·Recruiting·Listed Feb 2023

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A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

for Locally Advanced Solid Tumors

12 locations incl. Los Angeles

Sponsor: Turning Point Therapeutics, Inc.

Sex: All·Age: Up to 25

Code: NCT04094610·Phase 1, Phase 2·Recruiting·Listed Sep 2019

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Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B

for Hemophilia B

5 locations incl. Orange

Sponsor: CSL Behring

Sex: Male·Age: 138 Months - 206 Months

Code: NCT07080905·Phase 3·Recruiting·Listed Jul 2025

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A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's Ataxia

for Friedreich Ataxia

7 locations incl. Los Angeles

Sponsor: Biogen

Sex: All·Age: 2 - 15

Code: NCT06953583·Phase 3·Recruiting·Listed May 2025

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Palliative Care Integration in Pediatric Oncology Phase 1 Clinical Trials

for Quality of Life Outcomes

3 locations incl. Phoenix

Sponsor: Phoenix Children's Hospital

Sex: All·Age: 0 - 25

Code: NCT07696065·EARLY_Phase 1·Recruiting·Listed Jul 10, 2026

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Functional Evaluation in Patients With Urea Cycle Disorders (UCD) During a Driving Task

for Urea Cycle Disorder

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 16 - 40·Accepts healthy volunteers

Code: NCT07701694·Recruiting·Listed Jul 14, 2026

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Bereaved Parent Conversations on Hope

for Hope

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07675083·Recruiting·Listed Jun 2026

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Collaboration for Down Syndrome Progress (CDP)

for Down Syndrome

16 locations incl. Orange

Sponsor: RTI International

Sex: All·Age: All ages

Code: NCT07625579·Recruiting·Listed Jun 2026

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Feasibility of Incorporating a Standardized Substance Use Measure With Linked-Brief Intervention Into Routine Psychosocial Care of Adult Childhood Cancer Survivors

for Survivors of Childhood Cancer

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 15+

Code: NCT07516301·Recruiting·Listed Apr 2026

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Deep Phenotyping Gait Deficits in Orthopedic Manifestations of Pediatric Cancer Patients

for Sarcoma, Bone

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 5 - 20·Accepts healthy volunteers

Code: NCT07502885·Recruiting·Listed Mar 2026

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Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma

for Pediatric Osteosarcoma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT07428993·Phase 2·Recruiting·Listed Feb 2026

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Outcomes of Health Care Transition for AYA With a Cancer Predisposition

for Genetic Predisposition

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+

Code: NCT07456904·Recruiting·Listed Mar 2026

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A Longitudinal Photo-Narrative Exploration of Hope During Phase 1/2 Clinical Trials For Pediatric Cancer

for Cancer, Therapy-Related

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 12+

Code: NCT07444216·Recruiting·Listed Mar 2026

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Functional Ovarian Reserve in Sickle Cell Disease

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: Female·Age: 10 - 18·Accepts healthy volunteers

Code: NCT07392216·Recruiting·Listed Feb 2026

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Stakeholders of Rare Diseases Informing Values In Neuroethics

for Rare Disorder

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT07314736·Recruiting·Listed Jan 2026

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CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

for Relapsed Pediatric ALL

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT07257419·Phase 1·Recruiting·Listed Dec 2025

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Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma

for Posterior Fossa Ependymal Tumor

10 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 1 - 39

Code: NCT07226453·Phase 2·Recruiting·Listed Nov 2025

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Evaluation Of Cardiovascular Health Outcomes Among Survivors 2

for Health Behavior

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 26+

Code: NCT07245420·Recruiting·Listed Nov 2025

Apply to this trial

Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 8 - 17

Code: NCT07226219·Phase 1·Recruiting·Listed Nov 2025

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

45 locations incl. Phoenix

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting·Listed Jan 2022

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Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia

for Survivor of Childhood Cancer

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 20 - 50

Code: NCT07191119·Recruiting·Listed Sep 2025

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Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

for BRAF V600 Mutation

10 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 12 Months - 25

Code: NCT07110246·Phase 2·Recruiting·Listed Aug 2025

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Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial

for Childhood Cancer Survivor

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 10 - 17

Code: NCT07160621·Recruiting·Listed Sep 2025

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A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

for Neuroblastoma Recurrent

5 locations incl. San Francisco

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 30

Code: NCT07085338·Phase 2·Recruiting·Listed Jul 2025

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Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity

for Acute Lymphoblastic Leukemia

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+

Code: NCT07228741·Phase 2·Recruiting·Listed Nov 2025

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Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

for Refractory Acute Myeloid Leukemia

10 locations incl. San Diego

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 1 - 30

Code: NCT06177067·Phase 1·Recruiting·Listed Dec 2023

Apply to this trial

Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study

for Friedreich Ataxia

9 locations incl. Los Angeles

Sponsor: Friedreich's Ataxia Research Alliance

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06016946·Recruiting·Listed Aug 2023

Apply to this trial

Feasibility of High Intensity Interval Training in Survivors of Childhood, Adolescent, and Young Adult Hodgkin Lymphoma

for Hodgkin Lymphoma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 10 - 25

Code: NCT07222345·Recruiting·Listed Oct 2025

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Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

for T-cell Acute Lymphoblastic Leukemia

4 locations incl. San Diego

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 1 - 18

Code: NCT06390319·Phase 2·Recruiting·Listed Apr 2024

Apply to this trial

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

76 locations incl. Phoenix

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting·Listed May 2020

Apply to this trial

Revealing Information Genuinely & Honestly Across Time - Communication Preferences Visit

for Cancer

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT06993688·Recruiting·Listed May 2025

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Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children

for Hemorrhagic Shock

20 locations incl. Tucson

Sponsor: Philip Spinella

Sex: All·Age: Up to 17

Code: NCT06070350·Phase 3·Recruiting·Listed Oct 2023

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NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

for Neuroblastoma

13 locations incl. Los Angeles

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 1 - 31

Code: NCT06450041·Phase 2·Recruiting·Listed Jun 2024

Apply to this trial

Cardiopulmonary Function and Cerebral Blood Flow in Hodgkin Lymphoma Survivors

for Hodgkin Lymphoma, Adult

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06421987·Recruiting·Listed May 2024

Apply to this trial

Study of CD19 Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia

for Acute Lymphoblastic Leukemia, in Relapse

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04881240·Phase 1·Recruiting·Listed May 2021

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Family Intervention for Black Teens With Type 1 Diabetes

for Type 1 Diabetes

4 locations incl. Washington D.C.

Sponsor: Wayne State University

Sex: All·Age: 10 - 14

Code: NCT06275412·Recruiting·Listed Feb 2024

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Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Exposed to HIV-1

for HIV-1

9 locations incl. Los Angeles

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: Up to 72 Hours·Accepts healthy volunteers

Code: NCT06517693·Phase 1·Recruiting·Listed Jul 2024

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Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

for Acute Lymphoblastic Leukemia

5 locations incl. San Diego

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 1 - 18

Code: NCT06289673·Phase 4·Recruiting·Listed Mar 2024

Apply to this trial

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