Thomas jefferson University

Clinical research site in Philadelphia, Pennsylvania · 111 S 11TH ST, SUITE 8270, PHILADELPHIA, PA 19107-4824 · (215) 955-4038 · Website

Part of Thomas Jefferson University

As of July 2026, 88 paid clinical trials are recruiting at Thomas jefferson University in Philadelphia, Pennsylvania. Active studies at this site cover conditions such as Focal Epilepsy and Advanced Melanoma. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

Recruiting clinical trials at Thomas jefferson University (88)

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

for Obesity

206 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07567001·Phase 3·Recruiting·Listed May 2026

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A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications

for Parkinson's Disease

26 locations incl. Phoenix

Sponsor: Bayer

Sex: All·Age: 45 - 75

Code: NCT07330258·Recruiting·Listed Jan 2026

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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

for Diabetes Mellitus, Type 2

211 locations incl. Anniston

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07064473·Phase 3·Recruiting·Listed Jul 2025

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A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

for Colorectal Neoplasms

68 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06750094·Phase 3·Recruiting·Listed Dec 2024

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A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for Colorectal Neoplasms

79 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06662786·Phase 3·Recruiting·Listed Oct 2024

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A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults

for Episodic Migraine

68 locations incl. Birmingham

Sponsor: Ipsen

Sex: All·Age: 18 - 80

Code: NCT06625060·Phase 2·Recruiting·Listed Oct 2024

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Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

for Primary Biliary Cholangitis

51 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06051617·Phase 3·Recruiting·Listed Sep 2023

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A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

for Chronic Lymphocytic Leukemia

35 locations incl. Laguna Hills

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06943872·Phase 3·Recruiting·Listed Apr 2025

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FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

for Urinary Bladder Neoplasms

41 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05614739·Phase 1·Recruiting·Listed Nov 2022

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A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

for Leukemia, Myeloid, Acute

51 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06852222·Phase 3·Recruiting·Listed Feb 2025

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VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for Advanced Melanoma

44 locations incl. Gilbert

Sponsor: Replimune, Inc.

Sex: All·Age: 12+

Code: NCT06264180·Phase 3·Recruiting·Listed Feb 2024

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Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature

for Peripheral Vascular Diseases

38 locations incl. Jonesboro

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT04674969·Recruiting·Listed Dec 2020

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A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy

for Kidney Disease

40 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06963827·Phase 3·Recruiting·Listed May 2025

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An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

for Progressive Pulmonary Fibrosis

25 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06951217·Phase 2·Recruiting·Listed Apr 2025

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Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostate Cancer

23 locations incl. Duarte

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT04221542·Phase 1·Recruiting·Listed Jan 2020

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Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

for Relapsed Non-Hodgkin Lymphoma

32 locations incl. Irvine

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT05826535·Phase 1, Phase 2·Recruiting·Listed Apr 2023

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Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

for Pulmonary Hypertension

30 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT06911632·Recruiting·Listed Apr 2025

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A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

for Focal Epilepsy

48 locations incl. Phoenix

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06132893·Phase 2, Phase 3·Recruiting·Listed Nov 2023

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A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

for Type 1 Diabetes Mellitus With Hypoglycemia

37 locations incl. Birmingham

Sponsor: Zucara Therapeutics Inc.

Sex: All·Age: 18 - 75

Code: NCT05762107·Phase 2·Recruiting·Listed Mar 2023

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The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

for Functional Mitral Regurgitation

51 locations incl. Gilbert

Sponsor: Cardiac Dimensions, Inc.

Sex: All·Age: 18+

Code: NCT03142152·Recruiting·Listed May 2017

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A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

for Metastatic Uveal Melanoma

29 locations incl. Scottsdale

Sponsor: Replimune, Inc.

Sex: All·Age: All ages

Code: NCT06581406·Phase 2, Phase 3·Recruiting·Listed Sep 2024

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IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

for Advanced Melanoma

33 locations incl. Tucson

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT06112314·Phase 3·Recruiting·Listed Nov 2023

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A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

for Gastrointestinal Stromal Tumor (GIST)

32 locations incl. Birmingham

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06655246·Phase 1·Recruiting·Listed Oct 2024

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DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

for Venous Thromboembolism

33 locations incl. Scottsdale

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT05701917·Recruiting·Listed Jan 2023

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A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

for Cancer Harboring BRAF Alterations

29 locations incl. Beverly Hills

Sponsor: Fore Biotherapeutics

Sex: All·Age: 10+

Code: NCT05503797·Phase 2·Recruiting·Listed Aug 2022

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CAR-T Long Term Follow Up (LTFU) Study

for Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program

41 locations incl. Duarte

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT02445222·Phase 3·Recruiting·Listed May 2015

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Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus

for Esophageal Stricture

34 locations incl. Birmingham

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561114·Phase 3·Recruiting·Listed Sep 2022

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Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel

for Bowel

33 locations incl. Scottsdale

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561127·Phase 3·Recruiting·Listed Sep 2022

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Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

for Pancreatic Cancer

23 locations incl. Phoenix

Sponsor: Immuneering Corporation

Sex: All·Age: 18+

Code: NCT07562152·Phase 3·Recruiting·Listed May 2026

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AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

for KRAS Altered Advanced or Metastatic Solid Tumors

10 locations incl. Duarte

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT07094113·Phase 1·Recruiting·Listed Jul 2025

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Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

for Vascular Disease

24 locations incl. Tucson

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06658730·Recruiting·Listed Oct 2024

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A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

for Lymphoma

17 locations incl. La Jolla

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06624085·Phase 1·Recruiting·Listed Oct 2024

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RevCore for In Stent Thrombosis

for In-stent Thrombosis

16 locations incl. New Haven

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06394739·Recruiting·Listed May 2024

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A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

23 locations incl. Phoenix

Sponsor: Syncromune, Inc.

Sex: Male·Age: 18+

Code: NCT06533644·Phase 2·Recruiting·Listed Aug 2024

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Vivistim Registry for Paired VNS Therapy (GRASP)

for Upper Extremity Problem

15 locations incl. Orlando

Sponsor: MicroTransponder Inc.

Sex: All·Age: 22+

Code: NCT05301140·Recruiting·Listed Mar 2022

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Open-label Study of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH)

for Secondary Hemophagocytic Lymphohistiocytosis (sHLH)

16 locations incl. Birmingham

Sponsor: Electra Therapeutics Inc.

Sex: All·Age: 6+

Code: NCT05416307·Phase 2, Phase 3·Recruiting·Listed Jun 2022

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A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

for Acromegaly

10 locations incl. Los Angeles

Sponsor: Debiopharm International SA

Sex: All·Age: 18+

Code: NCT06930625·Phase 3·Recruiting·Listed Apr 2025

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Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

for EPP

15 locations incl. Huntington Beach

Sponsor: Tanabe Pharma America, Inc.

Sex: All·Age: 12 - 75

Code: NCT05005975·Phase 3·Recruiting·Listed Aug 2021

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Pilot/Pivotal Study of DBS+Rehab After Stroke

for Stroke

9 locations incl. Phoenix

Sponsor: Enspire DBS Therapy, Inc.

Sex: All·Age: 21+

Code: NCT05701280·Recruiting·Listed Jan 2023

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Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer (mCRPC)

5 locations incl. Philadelphia

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT07493512·Phase 1·Recruiting·Listed Mar 2026

Apply to this trial

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Paid clinical trials in Philadelphia, PA · Pennsylvania clinical trials