VA Medical Center, Durham

Clinical research site in Durham, North Carolina · 508 FULTON ST, DURHAM, NC 27705-3875 · (919) 286-0411

As of September 2026, 48 paid clinical trials are recruiting at VA Medical Center, Durham in Durham, North Carolina. Active studies at this site cover conditions such as Tobacco Use Disorder and Hearing Loss. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 1, 2026.

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Recruiting clinical trials at VA Medical Center, Durham (48)

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

39 locations incl. Phoenix

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07258511·Phase 3·Recruiting·Listed Dec 2025

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A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for Diabetes Mellitus, Type 2

123 locations incl. Chandler

Sponsor: Cleerly, Inc.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT06112418·Recruiting·Listed Nov 2023

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A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

66 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05552222·Phase 3·Recruiting·Listed Sep 2022

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06703073·Phase 2·Recruiting·Listed Nov 2024

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701656·Phase 2·Recruiting·Listed Nov 2024

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701669·Phase 2·Recruiting·Listed Nov 2024

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701682·Phase 2·Recruiting·Listed Nov 2024

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

623 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

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Increasing Germline Genetic Testing for Patients With Cancer

for Hereditary Pancreatic Cancer

10 locations incl. Los Angeles

Sponsor: Josh Peterson

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07307664·Recruiting·Listed Dec 2025

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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

618 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting·Listed Apr 2022

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

297 locations incl. Tucson

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020

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Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

for Advanced Lung Non-Small Cell Carcinoma

269 locations incl. Fayetteville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 70+

Code: NCT06096844·Phase 3·Recruiting·Listed Oct 2023

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Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

for Lung Non-Small Cell Carcinoma

266 locations incl. Jonesboro

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06498635·Phase 3·Recruiting·Listed Jul 2024

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Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

for Cigarette Smoking-Related Carcinoma

207 locations incl. Kingman

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05008848·Phase 3·Recruiting·Listed Aug 2021

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Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

for Castration-Sensitive Prostate Carcinoma

195 locations incl. Tucson

Sponsor: Alliance for Clinical Trials in Oncology

Sex: Male·Age: 18+

Code: NCT06931340·Phase 3·Recruiting·Listed Apr 2025

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Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

for Previously Treated Non-Small Cell Lung Cancer

950 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03851445·Phase 2, Phase 3·Recruiting·Listed Feb 2019

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Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

372 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642572·Phase 2·Recruiting·Listed Dec 2022

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Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

for Pancreatic Neoplasm

335 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 50 - 75

Code: NCT04239573·Recruiting·Listed Jan 2020

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Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for Prostate Adenocarcinoma

399 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT05946213·Phase 3·Recruiting·Listed Jul 2023

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

381 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

91 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting·Listed Feb 2020

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Implementing a Mobile Health Application for Women Veterans With Urinary Incontinence (MyHealtheBladder): Function QUERI 3.0

for Urinary Incontinence

1 location in Durham

Sponsor: VA Office of Research and Development

Sex: Female·Age: All ages

Code: NCT07219433·Recruiting·Listed Oct 2025

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Evaluating Treatments for Suicidal Veterans With PTSD

for Self-directed Violence

4 locations incl. Minneapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05974631·Recruiting·Listed Aug 2023

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Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

for Carcinoma, Hepatocellular

33 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05486572·Recruiting·Listed Aug 2022

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A New Intervention to Improve Function in Veterans With Anxiety and Depression

for Anxiety and Depression

1 location in Durham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 65

Code: NCT06188923·Phase 2·Recruiting·Listed Jan 2024

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International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

35 locations incl. Tuscaloosa

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting·Listed May 2017

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Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0

for Chronic Insomnia

1 location in Durham

Sponsor: VA Office of Research and Development

Sex: All·Age: 60+

Code: NCT07216261·Recruiting·Listed Oct 2025

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Implementing a Group Physical Therapy Program for Veterans (GroupPT): Function QUERI 3.0

for Knee Osteoarthritis

1 location in Durham

Sponsor: VA Office of Research and Development

Sex: All·Age: All ages

Code: NCT07215572·Recruiting·Listed Oct 2025

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ERP to Improve Functioning in Veterans With OCD

for Obsessive Compulsive Disorder (OCD)

19 locations incl. East Orange

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05240924·Recruiting·Listed Feb 2022

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Preserving Physical Function in Older Adults With Cancer: Impact of an Optimizing Nutrition Intervention Applied Before and After Surgery

for Cancer

1 location in Durham

Sponsor: VA Office of Research and Development

Sex: All·Age: 55+

Code: NCT05912257·Recruiting·Listed Jun 2023

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Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

for Prostate Cancer

16 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT04787744·Phase 2, Phase 3·Recruiting·Listed Mar 2021

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The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial

for Coronary Artery Disease

9 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05618353·Phase 4·Recruiting·Listed Nov 2022

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Pharmacogenomic Informed Statin Prescribing

for Hypercholesterolemia

2 locations incl. Indianapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 40 - 75

Code: NCT06568601·Recruiting·Listed Aug 2024

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Family Involvement in Treatment for PTSD (FIT-PTSD): A Brief, Feasible Method for Enhancing Outcomes, Retention, and Engagement

for Posttraumatic Stress Disorder

3 locations incl. Boston

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05267665·Recruiting·Listed Mar 2022

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Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

for Lung Neoplasm

14 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT02984761·Recruiting·Listed Dec 2016

Apply to this trial

Self-Injury Treatment and Recovery in Veterans

for Self-Injurious Behavior

1 location in Durham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05969080·Recruiting·Listed Aug 2023

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Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD

for Tobacco Use Disorder

1 location in Durham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05723588·Phase 2·Recruiting·Listed Feb 2023

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Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

for Prediabetic State

38 locations incl. Phoenix

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT02915198·Phase 4·Recruiting·Listed Sep 2016

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High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

for Metastatic Prostate Cancer

17 locations incl. Aurora

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05011383·Phase 2·Recruiting·Listed Aug 2021

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Supporting Health in Veterans With Heart Failure

for Heart Failure

4 locations incl. Gainesville

Sponsor: Florida State University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05839067·Recruiting·Listed May 2023

Apply to this trial

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Durham VA Medical Center (17 trials)
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