Wake Forest Baptist Health

Clinical research site in Winston-Salem, North Carolina · MEDICAL CENTER BLVD, WINSTON-SALEM, NC 27157-0001 · (336) 716-2255

Part of Wake Forest University

As of July 2026, 166 paid clinical trials are recruiting at Wake Forest Baptist Health in Winston-Salem, North Carolina. Active studies at this site cover conditions such as Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia Post Cytotoxic Therapy. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

Recruiting clinical trials at Wake Forest Baptist Health (166)

A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

for Clostridioides Difficile Associated Disease

135 locations incl. Athens

Sponsor: Pfizer

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07282665·Phase 3·Recruiting·Listed Dec 2025

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This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment

for Atopic Dermatitis

43 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT07290803·Recruiting·Listed Dec 2025

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OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

for Cardiovascular Disease

201 locations incl. Alexander City

Sponsor: Amgen

Sex: All·Age: 50 - 105

Code: NCT07136012·Phase 3·Recruiting·Listed Aug 2025

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Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

for Atherosclerotic Cardiovascular Disease

138 locations incl. Daphne

Sponsor: Amgen

Sex: All·Age: 45 - 99

Code: NCT07037433·Phase 3·Recruiting·Listed Jun 2025

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A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for Diabetes Mellitus, Type 2

123 locations incl. Chandler

Sponsor: Cleerly, Inc.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT06112418·Recruiting·Listed Nov 2023

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A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

for Primary Generalized Tonic-Clonic Seizures

51 locations incl. Mobile

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 12+

Code: NCT05667142·Phase 3·Recruiting·Listed Dec 2022

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Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

for Progressive Pulmonary Fibrosis

74 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT05943535·Phase 3·Recruiting·Listed Jul 2023

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Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

for Heart Failure

85 locations incl. Alexander City

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT06736574·Phase 3·Recruiting·Listed Dec 2024

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Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostate Cancer

23 locations incl. Duarte

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT04221542·Phase 1·Recruiting·Listed Jan 2020

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Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma Refractory

12 locations incl. San Francisco

Sponsor: CellCentric Ltd.

Sex: All·Age: 18+

Code: NCT07096778·Phase 2·Recruiting·Listed Jul 2025

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DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

for Glioblastoma (GBM)

17 locations incl. Duarte

Sponsor: Diakonos Oncology Corporation

Sex: All·Age: 18+

Code: NCT06805305·Phase 2·Recruiting·Listed Feb 2025

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A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)

for Multiple Myeloma

11 locations incl. Los Angeles

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06953960·Phase 1, Phase 2·Recruiting·Listed May 2025

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A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

for Gastric Adenocarcinoma

10 locations incl. Orange

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT05365581·Phase 1·Recruiting·Listed May 2022

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A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Participants With Multiple Myeloma That is Resistant to Current Standard of Care Treatments

for Multiple Myeloma

13 locations incl. La Jolla

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05137054·Phase 1·Recruiting·Listed Nov 2021

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Device Global Registry for the IlluminOss Bone Stabilization System

for Traumatic Fracture

10 locations incl. Los Angeles

Sponsor: IlluminOss Medical, Inc.

Sex: All·Age: 50+

Code: NCT05206981·Recruiting·Listed Jan 2022

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Non-Invasive Preeclampsia Screening and Biobank

for Preeclampsia (PE)

20 locations incl. Glendale

Sponsor: Sequenom, Inc.

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06643741·Recruiting·Listed Oct 2024

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Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

for EPP

15 locations incl. Huntington Beach

Sponsor: Tanabe Pharma America, Inc.

Sex: All·Age: 12 - 75

Code: NCT05005975·Phase 3·Recruiting·Listed Aug 2021

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Total Shoulder Arthroplasty Multi-Center Registry

for Shoulder Arthroplasty

15 locations incl. Phoenix

Sponsor: Arthrex, Inc.

Sex: All·Age: 18 - 100

Code: NCT03511586·Recruiting·Listed Apr 2018

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A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)

for Myotonic Dystrophy Type 1 (DM1)

8 locations incl. San Carlos

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 64

Code: NCT06185764·Phase 1, Phase 2·Recruiting·Listed Dec 2023

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NIBP Validation Study

for Critical Illness

3 locations incl. Winston-Salem

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: All ages

Code: NCT05673408·Recruiting·Listed Jan 2023

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Prospective Clinical Evaluation of the BioFire Emerging Coronavirus Panel for the Detection of COVID-19 and Other Coronaviruses

for Coronavirus

6 locations incl. Los Angeles

Sponsor: BioFire Defense LLC

Sex: All·Age: All ages

Code: NCT07221097·Recruiting·Listed Oct 2025

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Treatment of Radiation and Cisplatin Induced Toxicities with Tempol

for Mucositis

8 locations incl. La Jolla

Sponsor: Matrix Biomed, Inc.

Sex: All·Age: 18+

Code: NCT03480971·Phase 2·Recruiting·Listed Mar 2018

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RIsE Stroke Mobility Study

for Acute Ischemic Stroke

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07638462·Recruiting·Listed Jun 10, 2026

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BOOST: Blended Onsite and Offsite Structured Exercise Training and Coaching

for Heart Failure With Preserved Ejection Fraction

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 55+

Code: NCT07413198·Recruiting·Listed Feb 2026

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Culturally Tailored Program for Food-Insecure Adults: SPICE-D

for Type 2 Diabetes Mellitus (T2D)

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07361341·Recruiting·Listed Jan 2026

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Telehealth and Remote Blood Pressure

for Hypertension

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18 - 45

Code: NCT07356518·Recruiting·Listed Jan 2026

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

1105 locations incl. Anchorage

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting·Listed May 2023

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Development of Quantitative Muscle Imaging as a Biomarker of Disease Endpoints in Myotonic Dystrophy

for Myotonic Dystrophy

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07362875·Recruiting·Listed Jan 2026

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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

922 locations incl. Fairhope

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021

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Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for Locally Advanced Cervical Adenocarcinoma

289 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07061977·Phase 3·Recruiting·Listed Jul 2025

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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

776 locations incl. Fairhope

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023

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Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

for Intracranial Meningioma

456 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT02523014·Phase 2·Recruiting·Listed Aug 2015

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

640 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

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Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for Childhood Extracranial Germ Cell Tumor

387 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT03067181·Phase 3·Recruiting·Listed Mar 2017

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Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for Muscle Invasive Bladder Urothelial Carcinoma

449 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05987241·Phase 2, Phase 3·Recruiting·Listed Aug 2023

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Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

for B Acute Lymphoblastic Leukemia

156 locations incl. Antioch

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18 - 39

Code: NCT03150693·Phase 3·Recruiting·Listed May 2017

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

430 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022

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Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

for Prostate Cancer (Adenocarcinoma)

359 locations incl. Anchorage

Sponsor: Canadian Cancer Trials Group

Sex: Male·Age: 18+

Code: NCT06592924·Phase 3·Recruiting·Listed Sep 2024

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A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

382 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5 - 60

Code: NCT05675410·Phase 3·Recruiting·Listed Jan 2023

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MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for Acute Myeloid Leukemia

328 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05564390·Phase 2·Recruiting·Listed Oct 2022

Apply to this trial

Showing the 40 most relevant of 166 recruiting trials at this site. Browse all with filters →

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Paid clinical trials in Winston-Salem, NC · North Carolina clinical trials