Paid Clinical Trials in Winston-Salem, NC
As of September 2026, 526 paid clinical trials are recruiting in Winston-Salem, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Winston-Salem offers studies at sites including Wake Forest University Health Sciences for conditions such as Acute Myeloid Leukemia, Multiple Myeloma, Breast Cancer, Malignant Solid Neoplasm. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Winston-Salem
Trials by drug in Winston-Salem
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Newly added in Winston-Salem
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
A Clinical Study to Evaluate the Efficacy and SPF of Two Test Materials According to an Adaptation of the Guidelines of the FDA Sunscreen Drug Products for Over-the-Counter Human Use
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
Comparative Self-collection for Cervical Cancer Screening Pivotal Study
456 clinical trials
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
Parasternal Extravascular ICD System Pivotal Clinical Investigation (ALARION EV) Study
Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
Top Research Study Locations in Winston-Salem
Researchers run research studies in Winston-Salem, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Wake Forest University Health Sciences | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy | 157 |
| Atrium Health Wake Forest Baptist | Aging, Chronic Lymphocytic Leukemia, Myelofibrosis | 47 |
| Wake Forest University | Heart Failure, Heart Failure With Preserved Ejection Fraction, ALS-Frontotemporal Dementia | 25 |
| Novant Health Forsyth Medical Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer | 20 |
| Atrium Health Wake Forest Baptist Comprehensive Cancer Center | Acute Myeloid Leukemia, Cancer, Leukemia, Myeloid, Acute | 19 |
| Wake Forest Baptist Comprehensive Cancer Center | Malignant Solid Neoplasm, Nonsmall Cell Lung Cancer Stage III, Angiosarcoma | 18 |
| Atrium Health Wake Forest Baptist Medical Center | Acute Decompensated Heart Failure, Amyotrophic Lateral Sclerosis, Back Pain | 17 |
| Wake Forest Baptist Medical Center | Acute Respiratory Failure, Alzheimer Disease, Atrial Fibrillation | 15 |
| Wake Forest Baptist Health | Acute Lymphocytic Leukemia, Acute Myelogenous Leukemia, Alzheimer's Disease | 11 |
| Wake Forest University School of Medicine | AHRF, ARDS (Moderate or Severe), Acute Kidney Injury (AKI) | 10 |
| Southeastern Research Center | Idiopathic Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis (IPF), Progressive Pulmonary Fibrosis | 8 |
| Wake Forest School of Medicine | Lung Diseases, Acute Respiratory Failure, Bone Loss | 7 |
| Wake Forest University Baptist Medical Center | Amputation, Antibiotic Side Effect, Aortic Stenosis | 6 |
| Novant Health Cancer Institute | Acute Myeloid Leukemia, in Relapse, MDS (Myelodysplastic Syndrome), Acute Myeloid Leukemia Refractory | 6 |
| Wake Forest NCORP Research Base | Breast Carcinoma, Cancer, Colorectal Carcinoma | 6 |
| GSK Investigational Site | Bronchiectasis, Influenza, Human, Irritable Bowel Syndrome | 5 |
| Wake Forest | Acute Kidney Injury, Anesthesia, Anesthesia Awareness | 5 |
| Novant Health | Anemia, Benign Liver Tumor, Colorectal Cancer | 4 |
| Wake Forest Health Sciences | Albuminuria, Angiotensin Hypertension, Autonomic Dysfunction | 4 |
| Wake Forest Baptist | Focal Epilepsy, AAA - Abdominal Aortic Aneurysm | 3 |
| Novant Health Oncology Specialists | Breast Cancer, Ovarian Cancer, Previously Treated Non-Small Cell Lung Cancer | 3 |
| Wake Forest University Health Sciences Department of Dermatology | Dermatologic Disease, ICD10 Code L40.9 for Psoriasis, Psoriasis | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Accellacare - Winston-Salem | Clostridoides Difficile Associated Disease, Migraine | 2 |
| Atrium Health-Wake Forest Baptist | Chronic Pain, TEE Image Quality | 2 |
Active & Upcoming Studies in Winston-Salem (2026)
Recruiting trials in Winston-Salem grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (153 active studies)
- A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma · Phase 3 · AbbVie
- A Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL) · Phase 1 · Wake Forest University Health Sciences
Neurology & pain (34 active studies)
- Study of the Pharmacokinetics, Safety, and Tolerability of ZONISADE in Children 1 Month to 17 Years of Age With Partial-onset Seizures · Phase 4 · Azurity Pharmaceuticals
- Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's Disease · Phase 2 · Wake Forest University Health Sciences
Cardiovascular (31 active studies)
- Tailoring TM-HTN Intervention for Black Patients · Wake Forest University Health Sciences
- INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery · Abiomed Inc.
Diabetes & metabolic (22 active studies)
- Vibegron for ENergy Thinking and Resilience in Aging · Phase 3 · Wake Forest University Health Sciences
- Continuous Glucose Monitoring in Patients Undergoing Cardiopulmonary Bypass · Wake Forest University Health Sciences
Mental health & behavior (12 active studies)
- Supporting Families in the ICU · Indiana University
- Enhancing Slow Wave Sleep in Depression · Wake Forest University Health Sciences
HIV / STI (8 active studies)
- Supporting Health and Empowerment Through Contingency Management and Affect Regulation · Wake Forest University Health Sciences
- Study of GS-0415 and How It Works in People With HIV · Phase 1 · Gilead Sciences
Pediatric (6 active studies)
- The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma · Phase 2 · Wake Forest University Health Sciences
- Comprehensive Care for AYA: Needs Assessment Survey · Wake Forest University Health Sciences
Vaccines (4 active studies)
Eye & vision (3 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy · Phase 3 · Regeneron Pharmaceuticals
Common conditions studied in Winston-Salem
- Acute Myeloid Leukemia (11 active studies)
- Multiple Myeloma (10 active studies)
- Cancer (9 active studies)
- Breast Cancer (7 active studies)
- Malignant Solid Neoplasm (7 active studies)
- Hypertension (6 active studies)
Leading research sponsors in Winston-Salem
- Wake Forest University Health Sciences
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- AbbVie
Frequently asked questions
How many paid clinical trials are currently recruiting in Winston-Salem?
There are approximately 526 recruiting clinical trials in Winston-Salem, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Winston-Salem pay participants?
Most recruiting trials in Winston-Salem compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Winston-Salem?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Winston-Salem?
The most common conditions under active study in Winston-Salem include Acute Myeloid Leukemia (11), Multiple Myeloma (10), Cancer (9), Breast Cancer (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Winston-Salem?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Winston-Salem on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Winston-Salem?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Winston-Salem?
Recruiting research sites in Winston-Salem include Wake Forest University Health Sciences, Atrium Health Wake Forest Baptist, Wake Forest University, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Winston-Salem right now?
The largest active categories in Winston-Salem are Cancer & tumors (153), Neurology & pain (34), Cardiovascular (31). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.