Paid Clinical Trials in Winston-Salem, NC
As of August 2026, 537 paid clinical trials are recruiting in Winston-Salem, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Winston-Salem offers studies at sites including Wake Forest University Health Sciences for conditions such as Acute Myeloid Leukemia, Multiple Myeloma, Malignant Solid Neoplasm, Chronic Pain. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Winston-Salem
Trials by drug in Winston-Salem
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Newly added in Winston-Salem
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
An Observational Study of Patients With Dermatologic Disease
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
Comparing Two Acute Care Transition Programs for Older Adults and Their Family Caregivers
466 clinical trials
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
Parasternal Extravascular ICD System Pivotal Clinical Investigation (ALARION EV) Study
Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
A Study to Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis
A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Top Research Study Locations in Winston-Salem
Researchers run research studies in Winston-Salem, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Wake Forest University Health Sciences | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy | 168 |
| Atrium Health Wake Forest Baptist | Aging, Chronic Lymphocytic Leukemia, Myelofibrosis | 47 |
| Wake Forest University | Heart Failure, Heart Failure With Preserved Ejection Fraction, ALS-Frontotemporal Dementia | 23 |
| Novant Health Forsyth Medical Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer | 20 |
| Wake Forest Baptist Comprehensive Cancer Center | Malignant Solid Neoplasm, Nonsmall Cell Lung Cancer Stage III, Angiosarcoma | 19 |
| Atrium Health Wake Forest Baptist Comprehensive Cancer Center | Acute Myeloid Leukemia, Cancer, Leukemia, Myeloid, Acute | 18 |
| Atrium Health Wake Forest Baptist Medical Center | Acute Decompensated Heart Failure, Amyotrophic Lateral Sclerosis, Back Pain | 17 |
| Wake Forest Baptist Medical Center | Acute Respiratory Failure, Alzheimer Disease, Atrial Fibrillation | 14 |
| Wake Forest Baptist Health | Acute Lymphocytic Leukemia, Acute Myelogenous Leukemia, Alzheimer's Disease | 12 |
| Wake Forest University School of Medicine | AHRF, ARDS (Moderate or Severe), Acute Kidney Injury (AKI) | 10 |
| Southeastern Research Center | Idiopathic Pulmonary Fibrosis (IPF), Progressive Pulmonary Fibrosis, COPD | 8 |
| Wake Forest School of Medicine | Lung Diseases, Sepsis, Septic Shock, Acute Respiratory Failure | 8 |
| Wake Forest University Baptist Medical Center | Amputation, Antibiotic Side Effect, Aortic Stenosis | 6 |
| Wake Forest NCORP Research Base | Breast Carcinoma, Cancer, Colorectal Carcinoma | 6 |
| Novant Health Cancer Institute | Acute Myeloid Leukemia, in Relapse, MDS (Myelodysplastic Syndrome), Acute Myeloid Leukemia Refractory | 5 |
| Wake Forest | Acute Kidney Injury, Anesthesia, Anesthesia Awareness | 5 |
| Wake Forest Baptist | Focal Epilepsy, AAA - Abdominal Aortic Aneurysm, Community-acquired Pneumonia | 4 |
| GSK Investigational Site | Irritable Bowel Syndrome, Multiple Myeloma, Newly Diagnosed Multiple Myeloma | 4 |
| Novant Health | Anemia, Benign Liver Tumor, Colorectal Cancer | 4 |
| Wake Forest Health Sciences | Albuminuria, Angiotensin Hypertension, Autonomic Dysfunction | 4 |
| Wake Forest University Baptist Health | Androgenic Alopecia, EPP, Gastric Adenocarcinoma | 3 |
| Wake Forest University Health Sciences Department of Dermatology | Dermatologic Disease, ICD10 Code L40.9 for Psoriasis, Psoriasis | 3 |
| Brookview Hills Research Associates Llc | Antineutrophil Cytoplasmic Antibody-associated Vasculitis, Atherosclerotic Cardiovascular Disease, Obesity | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Atrium Health-Wake Forest Bapt | Sickle Cell Disease, Thalassemia | 2 |
Active & Upcoming Studies in Winston-Salem (2026)
Recruiting trials in Winston-Salem grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (154 active studies)
- A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma · Phase 3 · AbbVie
- A Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL) · Phase 1 · Wake Forest University Health Sciences
Neurology & pain (36 active studies)
- Study of the Pharmacokinetics, Safety, and Tolerability of ZONISADE in Children 1 Month to 17 Years of Age With Partial-onset Seizures · Phase 4 · Azurity Pharmaceuticals
- Methadone Pharmacokinetics in Cardiac Surgery · Phase 4 · Wake Forest University Health Sciences
Cardiovascular (30 active studies)
- Tailoring TM-HTN Intervention for Black Patients · Wake Forest University Health Sciences
- A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis · Phase 2 · Beijing Inno Medicine Co., Ltd.
Diabetes & metabolic (20 active studies)
- Vibegron for ENergy Thinking and Resilience in Aging · Phase 3 · Wake Forest University Health Sciences
- Continuous Glucose Monitoring in Patients Undergoing Cardiopulmonary Bypass · Wake Forest University Health Sciences
Mental health & behavior (14 active studies)
- Auditory Stimulation for Insomnia and Depression · Wake Forest University Health Sciences
- Enhancing Slow Wave Sleep in Depression · Wake Forest University Health Sciences
HIV / STI (6 active studies)
- Quitting Matters Human Immunodeficiency Virus Hybrid Trial · Wake Forest University Health Sciences
- Project neuroARTEMIS · Wake Forest University Health Sciences
Pediatric (6 active studies)
- The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma · Phase 2 · Wake Forest University Health Sciences
- Comprehensive Care for AYA: Needs Assessment Survey · Wake Forest University Health Sciences
Vaccines (4 active studies)
- A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease · Phase 2 · Shionogi
- Prospective Clinical Evaluation of the BioFire Emerging Coronavirus Panel for the Detection of COVID-19 and Other Coronaviruses · BioFire Defense LLC
Eye & vision (4 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
Common conditions studied in Winston-Salem
- Acute Myeloid Leukemia (11 active studies)
- Cancer (10 active studies)
- Multiple Myeloma (10 active studies)
- Malignant Solid Neoplasm (7 active studies)
- Chronic Pain (6 active studies)
- Breast Cancer (5 active studies)
Leading research sponsors in Winston-Salem
- Wake Forest University Health Sciences
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- AbbVie
Frequently asked questions
How many paid clinical trials are currently recruiting in Winston-Salem?
There are approximately 537 recruiting clinical trials in Winston-Salem, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Winston-Salem pay participants?
Most recruiting trials in Winston-Salem compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Winston-Salem?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Winston-Salem?
The most common conditions under active study in Winston-Salem include Acute Myeloid Leukemia (11), Cancer (10), Multiple Myeloma (10), Malignant Solid Neoplasm (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Winston-Salem?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Winston-Salem on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Winston-Salem?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Winston-Salem?
Recruiting research sites in Winston-Salem include Wake Forest University Health Sciences, Atrium Health Wake Forest Baptist, Wake Forest University, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Winston-Salem right now?
The largest active categories in Winston-Salem are Cancer & tumors (154), Neurology & pain (36), Cardiovascular (30). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.