MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
for Lumbar Spinal Stenosis
Sites in Cedar Rapids, Waterloo +2341 more locations
Sponsor: Stryker Instruments
Sex: All·Age: 18+
Code: NCT03072927·Recruiting·Listed Mar 2017
Paid Clinical Trials in Cedar Rapids, IA
As of July 2026, 63 paid clinical trials are recruiting in Cedar Rapids, Iowa. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Cedar Rapids offers studies at sites including Oncology Associates at Mercy Medical Center for conditions such as Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Chronic Lymphocytic Leukemia, HER2-Negative Breast Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Cedar Rapids
Trials by drug in Cedar Rapids
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63 clinical trials
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
for Carcinoma, Non-Small-Cell Lung
Drug: Adagrasib
Sites in Cedar Rapids +49 more locations
Sponsor: Mirati Therapeutics Inc.
Sex: All·Age: 18+
Code: NCT06875310·Phase 3·Recruiting·Listed Mar 2025
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
for Extensive-stage Small-cell Lung Cancer
Sites in Cedar Rapids, Ames +32 more locations
Sponsor: BioNTech SE
Sex: All·Age: 18+
Code: NCT06712355·Phase 3·Recruiting·Listed Dec 2024
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
for Non-small Cell Lung Cancer
Sites in Cedar Rapids, Iowa City +37 more locations
Sponsor: BioNTech SE
Sex: All·Age: 18+
Code: NCT06712316·Phase 2, Phase 3·Recruiting·Listed Dec 2024
Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis
for Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps
Sites in Cedar Rapids +9 more locations
Sponsor: Airiver Medical, Inc.
Sex: All·Age: 18+
Code: NCT07290140·Recruiting·Listed Dec 2025
PAVE (Parallactic Visual-Field Enhancement) System for Treatment of Chronic Visual Field Loss Due to Stroke, Traumatic Brain Injury, or Brain Surgery
for Homonymous Hemianopsia
Sites in Cedar Rapids +1 more location
Sponsor: NeuroAEye LLC
Sex: All·Age: 21 - 80
Code: NCT07185971·Recruiting·Listed Sep 2025
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial
for Anatomic Stage II Breast Cancer AJCC v8
Drug: Ribociclib
Sites in Cedar Rapids, Marshalltown +70 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT07391774·Phase 3·Recruiting·Listed Feb 2026
Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial
for Lung Non-Small Cell Carcinoma
Drug: Atezolizumab
Sites in Cedar Rapids, Marshalltown +23 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT07388524·Phase 3·Recruiting·Listed Feb 2026
Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer
for Advanced Clear Cell Renal Cell Carcinoma
Sites in Cedar Rapids +40 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT07383441·Phase 3·Recruiting·Listed Feb 2026
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL
for Chronic Lymphocytic Leukemia
Drug: Sonrotoclax
Sites in Cedar Rapids, Pella +150 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 65+
Code: NCT07321652·Phase 3·Recruiting·Listed Jan 2026
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
for Ampulla of Vater Carcinoma
Sites in Cedar Rapids, Marshalltown +330 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07283939·Recruiting·Listed Dec 2025
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
for Advanced Endometrial Carcinoma
Drug: Bevacizumab
Sites in Cedar Rapids, Iowa City +235 more locations
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 18+
Code: NCT07198074·Phase 3·Recruiting·Listed Sep 2025
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
for Lung Non-Small Cell Carcinoma
Sites in Cedar Rapids, Marshalltown +633 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
Sites in Cedar Rapids, Iowa City +1103 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
for Chronic Lymphocytic Leukemia
Sites in Cedar Rapids, Marshalltown +296 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in Cedar Rapids, Iowa City +920 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
Sites in Cedar Rapids, Iowa City +774 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
for Locally Advanced Cervical Adenocarcinoma
Sites in Cedar Rapids, Iowa City +294 more locations
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 18+
Code: NCT07061977·Phase 3·Recruiting·Listed Jul 2025
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Cedar Rapids, Iowa City +641 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05677490·Phase 3·Recruiting·Listed Jan 2023
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for Anatomic Stage I Breast Cancer AJCC v8
Sites in Cedar Rapids, Marshalltown +583 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
for Acute Lymphoblastic Leukemia
Sites in Cedar Rapids, Marshalltown +629 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 40 - 75·Accepts healthy volunteers
Code: NCT05334069·Recruiting·Listed Apr 2022
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
for Anatomic Stage II Breast Cancer AJCC v8
Drug: Durvalumab
Sites in Cedar Rapids, Ankeny +525 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
for Extensive Stage Lung Small Cell Carcinoma
Drug: Atezolizumab
Sites in Cedar Rapids, Ankeny +271 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04402788·Phase 2, Phase 3·Recruiting·Listed May 2020
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
for Plasma Cell Myeloma
Sites in Cedar Rapids, Marshalltown +226 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT04566328·Phase 3·Recruiting·Listed Sep 2020
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
for Advanced Malignant Solid Neoplasm
Sites in Cedar Rapids, Ankeny +429 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: All ages
Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022
Mobile Health for Adherence in Breast Cancer Patients
for Anatomic Stage IV Breast Cancer AJCC v8
Sites in Cedar Rapids, Marshalltown +457 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06112613·Recruiting·Listed Nov 2023
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
for Clinical Stage III Cutaneous Melanoma AJCC v8
Drug: Cabozantinib
Sites in Cedar Rapids, Marshalltown +204 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05136196·Phase 2·Recruiting·Listed Nov 2021
Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors
for Hodgkin Lymphoma
Sites in Cedar Rapids, Marshalltown +403 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT06002828·Recruiting·Listed Aug 2023
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
for Advanced Lung Non-Small Cell Carcinoma
Sites in Cedar Rapids, Ankeny +267 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 70+
Code: NCT06096844·Phase 3·Recruiting·Listed Oct 2023
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
for Prostate Cancer (Adenocarcinoma)
Sites in Cedar Rapids, Pella +357 more locations
Sponsor: Canadian Cancer Trials Group
Sex: Male·Age: 18+
Code: NCT06592924·Phase 3·Recruiting·Listed Sep 2024
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
for Clear Cell Renal Cell Carcinoma
Sites in Cedar Rapids, Iowa City +403 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06661720·Phase 3·Recruiting·Listed Oct 2024
Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer
for Resectable Lung Non-Small Cell Carcinoma
Sites in Cedar Rapids +307 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06632327·Phase 3·Recruiting·Listed Oct 2024
E-Mindfulness Approaches for Living After Breast Cancer
for Breast Cancer
Sites in Cedar Rapids, Iowa City +355 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18 - 50
Code: NCT06748222·Phase 3·Recruiting·Listed Dec 2024
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
for Previously Treated Non-Small Cell Lung Cancer
Sites in Cedar Rapids, Iowa City +948 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT03851445·Phase 2, Phase 3·Recruiting·Listed Feb 2019
Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
for Plasma Cell Myeloma
Sites in Cedar Rapids, Iowa City +387 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: All ages
Code: NCT05561387·Phase 3·Recruiting·Listed Sep 2022
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
for Malignant Solid Neoplasm
Sites in Cedar Rapids +364 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: All ages·Accepts healthy volunteers
Code: NCT06295367·Recruiting·Listed Mar 2024
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
for Locally Advanced Lung Non-Small Cell Carcinoma
Sites in Cedar Rapids, Ames +444 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05624996·Phase 3·Recruiting·Listed Nov 2022
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
for Biochemically Recurrent Prostate Carcinoma
Drug: Apalutamide
Sites in Cedar Rapids +277 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: Male·Age: 18+
Code: NCT04423211·Phase 3·Recruiting·Listed Jun 2020
Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program
for Cigarette Smoking-Related Carcinoma
Sites in Cedar Rapids, Iowa City +204 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05008848·Phase 3·Recruiting·Listed Aug 2021
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Cedar Rapids, Ankeny +344 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06203600·Phase 2, Phase 3·Recruiting·Listed Jan 2024
Top Research Study Locations in Cedar Rapids
Researchers run research studies in Cedar Rapids, IA at 11 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Oncology Associates at Mercy Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma | 50 |
| Mercy Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma | 47 |
| Physicians' Clinic of Iowa PC | Lung Non-Small Cell Carcinoma, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 12 |
| Saint Luke's Hospital | Breast Cancer, Cigarette Smoking-Related Carcinoma, Depression | 5 |
| Dr. D. M. Fitzgerald & Associates | Homonymous Hemianopsia, Homonymous Quadrantanopia | 1 |
| Helen G. Nassif Community Cancer Center | Extensive-stage Small-cell Lung Cancer | 1 |
| Mercy Cedar Rapids | Lumbar Spinal Stenosis | 1 |
| Mercy Medical Center | Carcinoma, Non-Small-Cell Lung | 1 |
| Physicians Clinic of Iowa | Non-small Cell Lung Cancer | 1 |
| Physicians' Clinic of Iowa | Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps | 1 |
| St Lukes Hosp | Lumbar Spinal Stenosis | 1 |
Active & Upcoming Studies in Cedar Rapids (2026)
Recruiting trials in Cedar Rapids grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (56 active studies)
- Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial · Phase 3 · National Cancer Institute (NCI)
- Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial · Phase 3 · National Cancer Institute (NCI)
Mental health & behavior (2 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program · Phase 3 · Alliance for Clinical Trials in Oncology
Common conditions studied in Cedar Rapids
- Anatomic Stage II Breast Cancer AJCC v8 (5 active studies)
- Anatomic Stage IIIA Breast Cancer AJCC v8 (3 active studies)
- Chronic Lymphocytic Leukemia (3 active studies)
- HER2-Negative Breast Carcinoma (3 active studies)
- Lung Non-Small Cell Carcinoma (3 active studies)
- Malignant Solid Neoplasm (3 active studies)
Leading research sponsors in Cedar Rapids
- National Cancer Institute (NCI)
- Alliance for Clinical Trials in Oncology
- SWOG Cancer Research Network
- NRG Oncology
- ECOG-ACRIN Cancer Research Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Cedar Rapids?
There are approximately 63 recruiting clinical trials in Cedar Rapids, Iowa listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Cedar Rapids pay participants?
Most recruiting trials in Cedar Rapids compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Cedar Rapids?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Cedar Rapids?
The most common conditions under active study in Cedar Rapids include Anatomic Stage II Breast Cancer AJCC v8 (5), Anatomic Stage IIIA Breast Cancer AJCC v8 (3), Chronic Lymphocytic Leukemia (3), HER2-Negative Breast Carcinoma (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Cedar Rapids?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Cedar Rapids on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Cedar Rapids?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Cedar Rapids?
Recruiting research sites in Cedar Rapids include Oncology Associates at Mercy Medical Center, Mercy Hospital, Physicians' Clinic of Iowa PC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Cedar Rapids right now?
The largest active categories in Cedar Rapids are Cancer & tumors (56), Mental health & behavior (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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