Autoimmune disease Clinical Trials in Chicago, IL

As of July 2026, 55 paid clinical trials are recruiting for Autoimmune disease in Chicago, Illinois. Autoimmune disease research covers a broad spectrum of immune-modulating therapies — JAK inhibitors, biologics, T-cell modulators, and tolerance-inducing agents — across rheumatologic, dermatologic, neurologic, and GI conditions. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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55 clinical trials for Autoimmune disease

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Functional Balance Intervention in Multiple Sclerosis

for Multiple Sclerosis

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18 - 90

Code: NCT06341023·Recruiting·Listed Apr 2024

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Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis

for Multiple Sclerosis

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18 - 64

Code: NCT05051618·Recruiting·Listed Sep 2021

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Nomad P-KAFO Study

for Cerebrovascular Accident

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18 - 89

Code: NCT05644522·Recruiting·Listed Dec 2022

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Tissue Destruction and Healing in Celiac Disease

for Celiac Disease

Sites in Chicago +2 more locations

Sponsor: University of Chicago

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT05680012·Recruiting·Listed Jan 2023

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Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

for Atopic Dermatitis

Drug: Dupilumab

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 6 - 17

Code: NCT05042258·Phase 4·Recruiting·Listed Sep 2021

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The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing

for Patients Undergoing Routine Health Care

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01280825·Recruiting·Listed Jan 2011

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Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS

for Multiple Sclerosis

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18 - 75

Code: NCT06390930·Recruiting·Listed Apr 2024

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Evaluation of the Safety and Efficacy of a Full-Body Electrostimulation Garment for Individuals With Neurological and Neuromuscular Conditions That Cause Spasticity, Hyperreflexia, and Pain

for Multiple Sclerosis

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18 - 75

Code: NCT07132775·Recruiting·Listed Aug 2025

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Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

for Ulcerative Colitis

Sites in Chicago +18 more locations

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT05230173·Recruiting·Listed Feb 2022

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Intermittent Hypoxia in Persons With Multiple Sclerosis

for Multiple Sclerosis

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18 - 75

Code: NCT06276634·Recruiting·Listed Feb 2024

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Development of Camera Based Gait Quality Measure for Persons With Multiple Sclerosis

for Multiple Sclerosis

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18 - 75

Code: NCT06516458·Recruiting·Listed Jul 2024

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A Study of AZD0120 in Autoimmune Diseases

for Systemic Sclerosis

Sites in Chicago +7 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT07295847·Phase 1·Recruiting·Listed Dec 2025

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A Study to Investigate OCS Tapering in Adult Participants With Generalized Myasthenia Gravis Treated With Ravulizumab

for Generalized Myasthenia Gravis

Sites in Chicago, Schaumburg +3 more locations

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07221838·Phase 4·Recruiting·Listed Oct 2025

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An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

for Systemic Lupus Erythematosus

Sites in Chicago +19 more locations

Sponsor: AstraZeneca

Sex: All·Age: 5 - 17

Code: NCT05835310·Phase 3·Recruiting·Listed Apr 2023

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A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

for Systemic Sclerosis

Sites in Chicago +13 more locations

Sponsor: Nkarta, Inc.

Sex: All·Age: 18 - 75

Code: NCT06733935·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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Conditions in Autoimmune disease (Chicago, IL)

Multiple sclerosis· 13 Ulcerative colitis· 11 Crohn's disease· 9 Atopic dermatitis / eczema· 8 Rheumatoid arthritis· 5 Myasthenia gravis· 5 Inflammatory bowel disease (IBD)· 4 Lupus (SLE)· 3 Psoriatic arthritis· 2 Hidradenitis suppurativa· 2 Autoimmune diseases (general)· 2 Celiac disease· 2 Psoriasis· 1