Lung oncology Clinical Trials in Chicago, IL

As of August 2026, 61 paid clinical trials are recruiting for Lung oncology in Chicago, Illinois. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 31, 2026.

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62 clinical trials for Lung oncology

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Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Chicago, Maywood +255 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500455·Phase 3·Recruiting·Listed Jul 2024

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Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

for Non-small Cell Lung Cancer

Sites in Chicago, Oak Brook +69 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06686771·Phase 3·Recruiting·Listed Nov 2024

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Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Chicago, Warrenville +56 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500481·Phase 3·Recruiting·Listed Jul 2024

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A Registry for People With Lung Cancer

for Lung Cancer

Sites in Chicago, Evanston +14 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06424327·Recruiting·Listed May 2024

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A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

for Malignant Peritoneal Mesothelioma

Sites in Chicago +12 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06057935·Phase 2·Recruiting·Listed Sep 2023

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

Sites in Chicago, Maywood +241 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting·Listed Nov 2023

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Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

Sites in Chicago, Oak Lawn +462 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting·Listed May 2024

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Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

for Non Small Cell Lung Cancer

Drug: Osimertinib

Sites in Chicago, Oak Lawn +144 more locations

Sponsor: PrECOG, LLC.

Sex: All·Age: 18+

Code: NCT06538038·Recruiting·Listed Aug 2024

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Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma

for Mesothelioma

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT07126509·Recruiting·Listed Aug 2025

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Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)

for Small-cell Lung Cancer

Drug: Durvalumab

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT05068232·Phase 2·Recruiting·Listed Oct 2021

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Lung Cancer Screening in High-risk Black Individuals

for Lung Cancer

Sites in Chicago +1 more location

Sponsor: Massachusetts General Hospital

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT05898594·Recruiting·Listed Jun 2023

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LUNG-05: Investigating Chemotherapy Effectiveness for Non-Small Cell Lung Cancer (NSCLC) Metastatic Patients

for NSCLC

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT06576635·Recruiting·Listed Aug 2024

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Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

for Stage IV NSCLC

Sites in Chicago +3 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06671613·Recruiting·Listed Nov 2024

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Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study

for Lung Carcinoma

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT05802186·Recruiting·Listed Apr 2023

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Olaparib in Patients With HRD Malignant Mesothelioma

for Mesothelioma

Drug: Olaparib

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT04515836·Phase 2·Recruiting·Listed Aug 2020

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DREAM: Double Lung Transplant REgistry Aimed for Lung-limited Malignancies

for Lung Cancer

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 75

Code: NCT05671887·Recruiting·Listed Jan 2023

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I3LUNG: Integrative Science, Intelligent Data Platform for Individualized LUNG Cancer Care With Immunotherapy

for Non Small Cell Lung Cancer

1 location in Chicago

Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Sex: All·Age: 18+

Code: NCT05537922·Recruiting·Listed Sep 2022

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

Sites in Chicago, Niles +46 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting·Listed Dec 2025

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Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for Non-small Cell Lung Cancer

Sites in Chicago +17 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06218914·Phase 1·Recruiting·Listed Jan 2024

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Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

for Non-small Cell Lung Cancer

Sites in Chicago +18 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 95

Code: NCT05061550·Phase 2·Recruiting·Listed Sep 2021

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Chicago, Hinsdale +63 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06692738·Phase 3·Recruiting·Listed Nov 2024

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Conditions in Lung oncology (Chicago, IL)

Non-small cell lung cancer (NSCLC)· 48 Lung cancer· 17 Mesothelioma· 5 Small cell lung cancer· 3