Clinical Trials at Northwestern University

As of September 2026, 311 paid clinical trials are recruiting at Northwestern University, located at 303 E CHICAGO AVE, TARRY BUILDING, 11-703, CHICAGO, IL 60611-3008, phone (312) 503-0830 in Chicago, Illinois. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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313 clinical trials at Northwestern University

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Bowel Continence Across the Lifespan in People With Spina Bifida

for Spina Bifida

Sites in Chicago +23 more locations

Sponsor: David Chu

Sex: All·Age: 5+

Code: NCT07390318·Recruiting·Listed Feb 2026

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Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

for Chronic Obstructive Pulmonary Disease (COPD)

Drug: Omalizumab

Sites in Chicago +20 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 40+

Code: NCT07059091·Phase 2·Recruiting·Listed Jul 2025

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Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

for Pleural Biphasic Mesothelioma

Sites in Chicago, Orland Park +102 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05647265·Phase 2·Recruiting·Listed Dec 2022

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Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

for Previously Treated Non-Small Cell Lung Cancer

Sites in Chicago, Oak Park +948 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03851445·Phase 2, Phase 3·Recruiting·Listed Feb 2019

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Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

for Astrocytoma, IDH-Mutant, Grade 2

Sites in Chicago +34 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06860594·Phase 1·Recruiting·Listed Mar 2025

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PREVENT ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Chicago +30 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06581861·Recruiting·Listed Sep 2024

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Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

for Advanced Malignant Solid Neoplasm

Sites in Chicago +26 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06311214·Phase 2·Recruiting·Listed Mar 2024

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Nutrition for Precision Health, Powered by the All of Us

for Nutrition

Sites in Chicago +11 more locations

Sponsor: RTI International

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05701657·Recruiting·Listed Jan 2023

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Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

for Advanced Malignant Solid Neoplasm

Sites in Chicago +21 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05327010·Phase 2·Recruiting·Listed Apr 2022

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Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Chicago, Warrenville +56 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500481·Phase 3·Recruiting·Listed Jul 2024

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Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

for Gastric Adenocarcinoma

Sites in Chicago, Oak Brook +76 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT07001748·Phase 2, Phase 3·Recruiting·Listed Jun 2025

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Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

for Recurrent Non-Muscle Invasive Bladder Carcinoma

Sites in Chicago, Maywood +56 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07000084·Phase 3·Recruiting·Listed May 2025

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Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Sites in Chicago, Oak Park +370 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642572·Phase 2·Recruiting·Listed Dec 2022

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National Liver Cancer Screening Trial

for Carcinoma, Hepatocellular

Sites in Chicago +18 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 85

Code: NCT06084234·Phase 4·Recruiting·Listed Oct 2023

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Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

for Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

Sites in Chicago, Warrenville +39 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18+

Code: NCT05646316·Phase 3·Recruiting·Listed Dec 2022

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Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

for Lactating Women on Select DOI

Sites in Chicago +12 more locations

Sponsor: Duke University

Sex: All·Age: All ages

Code: NCT03511118·Recruiting·Listed Apr 2018

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Evolution of the Chicago Classification: Bridging Physiology and Mechanics

for Dysphagia

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 85

Code: NCT06883175·Recruiting·Listed Mar 2025

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Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

for Non-small Cell Lung Cancer

Sites in Chicago, Oak Brook +69 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06686771·Phase 3·Recruiting·Listed Nov 2024

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ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for Frontotemporal Lobar Degeneration (FTLD)

Sites in Chicago +24 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04363684·Recruiting·Listed Apr 2020

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Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

for Metastatic Colorectal Carcinoma

Sites in Chicago +53 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT05863195·Phase 3·Recruiting·Listed May 2023

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Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer

for Estrogen-receptor-positive Breast Cancer

3 locations in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06062498·Phase 2·Recruiting·Listed Oct 2023

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Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

for Clinical Stage III Cutaneous Melanoma AJCC v8

Sites in Chicago, Shiloh +23 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05896839·Phase 1, Phase 2·Recruiting·Listed Jun 2023

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Efficacy of RestoreX Penile Traction Therapy In Preserving Erectile Function Post-Prostatectomy

for Erectile Dysfunction Following Radical Prostatectomy

Sites in Chicago +3 more locations

Sponsor: Charitable Union for the Research and Education of Peyronie's Disease

Sex: Male·Age: 18+

Code: NCT05244486·Recruiting·Listed Feb 2022

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The SEQUENCE Trial

for Pulmonary Nodules

Sites in Chicago +4 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06676956·Recruiting·Listed Nov 2024

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Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial

for Prostate Adenocarcinoma

Sites in Chicago +4 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT06022822·Phase 2·Recruiting·Listed Sep 2023

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Cemiplimab for the Treatment of Incurable Metastatic or Unresectable NUT Carcinoma

for Metastatic NUT Carcinoma

Drug: Cemiplimab

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07050186·Phase 2·Recruiting·Listed Jul 2025

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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for Cystic Fibrosis

Sites in Chicago, Peoria +57 more locations

Sponsor: Chris Goss

Sex: All·Age: 6+

Code: NCT05548283·Phase 4·Recruiting·Listed Sep 2022

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Functional Assessment in Liver Transplantation

for End Stage Liver Disease

Sites in Chicago +7 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT03228290·Recruiting·Listed Jul 2017

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

Sites in Chicago, Maywood +705 more locations

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021

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Developing a Digital Intervention for Adolescent Nonsuicidal Self-injury

for Nonsuicidal Self-injury

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 14 - 18

Code: NCT07224165·Recruiting·Listed Nov 2025

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Tocilizumab Discontinuation Versus Dose Reduction for Patients With Well-Controlled Giant Cell Arteritis

for Giant Cell Arteritis (GCA)

Drug: Tocilizumab

Sites in Chicago +6 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 50+

Code: NCT07108387·Phase 2·Recruiting·Listed Aug 2025

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Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

for Rectal Cancer

Sites in Chicago, Warrenville +101 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06205485·Phase 3·Recruiting·Listed Jan 2024

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Movement Amplification Gait Training to Enhance Walking Balance Post-Stroke

for Chronic Hemiparetic Stroke

Sites in Chicago & Hines

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80

Code: NCT06400186·Recruiting·Listed May 2024

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Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

for Newly Diagnosed Glioblastoma

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT05864534·Phase 2·Recruiting·Listed May 2023

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Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure

for Heart Failure With Reduced Ejection Fraction

Sites in Chicago +4 more locations

Sponsor: University of Colorado, Denver

Sex: All·Age: 18+

Code: NCT06526988·Recruiting·Listed Jul 2024

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

Sites in Chicago, Maywood +379 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024

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ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Chicago +35 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting·Listed Aug 2024

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Electrophysiological Representations of Odor in the Human Brain Study 1

for Odor Intensity Ratings

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 12 - 65

Code: NCT06769464·Recruiting·Listed Jan 2025

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Deep Functional Phenotyping of the ALA Lung Health Cohort

for Lung Diseases

Sites in Chicago +11 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT06177717·Recruiting·Listed Dec 2023

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Sites in Chicago, Maywood +239 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18 Minutes+

Code: NCT06031688·Phase 2·Recruiting·Listed Sep 2023

Apply to this trial