Clinical Trials at Northwestern University

As of September 2026, 311 paid clinical trials are recruiting at Northwestern University, located at 303 E CHICAGO AVE, TARRY BUILDING, 11-703, CHICAGO, IL 60611-3008, phone (312) 503-0830 in Chicago, Illinois. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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313 clinical trials at Northwestern University

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Platform Clinical Study for Conquering Scleroderma

for Interstitial Lung Disease Due to Systemic Disease

Sites in Chicago +23 more locations

Sponsor: Scleroderma Research Foundation, Inc.

Sex: All·Age: 18+

Code: NCT06195072·Phase 2·Recruiting·Listed Jan 2024

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Evaluating a Decreased Dose of Radiation Therapy to the Elective Neck for the Treatment of HPV-Related Oropharyngeal Cancer, ENLIGHT Trial

for Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

Sites in Chicago & Warrenville

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07178301·Phase 2·Recruiting·Listed Sep 2025

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Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

for Hiv

Sites in Chicago +17 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06263426·Recruiting·Listed Feb 2024

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Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

for Breast Atypical Ductal Hyperplasia

Sites in Chicago +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18 - 55

Code: NCT06184750·Phase 2·Recruiting·Listed Dec 2023

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

Sites in Chicago, Maywood +241 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting·Listed Nov 2023

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Electrophysiological Representations of Odor Identity Study 2

for Odor Identity Ratings

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 12 - 65

Code: NCT07386236·Recruiting·Listed Feb 2026

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WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

for Glioblastoma, IDH-Wildtype

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT05879250·Phase 2·Recruiting·Listed May 2023

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Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia

for Hypertension, Pregnancy-Induced

Sites in Chicago +1 more location

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18+

Code: NCT06220721·Recruiting·Listed Jan 2024

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Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for Epiretinal Membrane

Sites in Chicago, Oak Park +45 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05145491·Recruiting·Listed Dec 2021

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Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

for Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation

Sites in Chicago +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT05691465·Phase 2·Recruiting·Listed Jan 2023

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Micromanaging Human Sleep Physiology to Treat Sleep Apnea and Other Disorders

for Sleep Apnea Obstructive (OSA)

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 60

Code: NCT06926036·Recruiting·Listed Apr 2025

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PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

for Parkinson Disease

Sites in Chicago +29 more locations

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT04477785·Recruiting·Listed Jul 2020

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Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

for Breast Atypical Hyperplasia

Sites in Chicago +3 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 35+

Code: NCT05941520·Phase 2·Recruiting·Listed Jul 2023

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Proton-Spatially Fractionated Radiotherapy and Standard Radiation Therapy for the Treatment of Newly Diagnosed Retroperitoneal Soft Tissue Sarcoma

for Retroperitoneal Sarcoma

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06327477·Phase 1, Phase 2·Recruiting·Listed Mar 2024

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Epcoritamab and Lenalidomide in Treating Patients With Refractory or Relapsed Immunodeficiency-Related Large B-Cell Lymphoma

for Recurrent B-Cell Non-Hodgkin Lymphoma

Drug: Epcoritamab

1 location in Chicago

Sponsor: Reem Karmali

Sex: All·Age: 18+

Code: NCT06723457·Phase 2·Recruiting·Listed Dec 2024

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An Investigational Scan (rhPSMA-7.3 PET/CT) for Detecting Biochemically Recurrent Prostate Cancer, ENLIGHTEN Trial

for Biochemically Recurrent Prostate Carcinoma

1 location in Chicago

Sponsor: Northwestern University

Sex: Male·Age: All ages

Code: NCT06813898·EARLY_Phase 1·Recruiting·Listed Feb 2025

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Testing the Combination of Anti-cancer Drugs Mosunetuzumab, Polatuzumab Vedotin, and Lenalidomide for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

for Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

Drug: Polatuzumab Vedotin

Sites in Chicago +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06015880·Phase 1·Recruiting·Listed Aug 2023

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Chicago, Oak Park +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

Sites in Chicago, Maywood +144 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting·Listed Jan 2025

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XL092 for the Treatment of Locally Advanced or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer

for Locally Advanced Differentiated Thyroid Gland Carcinoma

Sites in Chicago +1 more location

Sponsor: Jochen Lorch

Sex: All·Age: 18+

Code: NCT06959641·Phase 2·Recruiting·Listed May 2025

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Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

for Metastatic Malignant Neoplasm in the Liver

Sites in Chicago, Orland Park +378 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05040360·Phase 2·Recruiting·Listed Sep 2021

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ALS/MND Natural History Study Data Repository

for ALS

Sites in Chicago +13 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting·Listed Jul 2023

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XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue Sarcoma

for Metastatic Leiomyosarcoma

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06571734·Phase 2·Recruiting·Listed Aug 2024

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Pathophysiology of Circadian Rhythm Delayed Sleep Wake Phase Disorder

for Delayed Sleep Phase Syndrome

Sites in Chicago +1 more location

Sponsor: University of Colorado, Boulder

Sex: All·Age: 16 - 40·Accepts healthy volunteers

Code: NCT06471374·Recruiting·Listed Jun 2024

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MINT Conditioning to Improve Gait

for Stroke

Sites in Chicago +1 more location

Sponsor: Northwestern University

Sex: All·Age: 18 - 85

Code: NCT07041775·Recruiting·Listed Jun 2025

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Pemetrexed Response in Relation to Tumor Alterations of Gene Status for the Treatment of Patients With Metastatic Urothelial Bladder Cancer and Other Solid Tumors

for Metastatic Bladder Urothelial Carcinoma

Sites in Chicago & Orland Park

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06630416·Phase 2·Recruiting·Listed Oct 2024

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IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

Sites in Chicago, Springfield +50 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting·Listed Oct 2023

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Pupillometry in Delayed Sleep Wake Phase Disorder

for Delayed Sleep-Wake Phase Disorder

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 16+

Code: NCT06949644·Recruiting·Listed Apr 2025

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Genomic Predictors of Recurrent Pregnancy Loss

for Recurrent Pregnancy Loss

Sites in Chicago +8 more locations

Sponsor: Yale University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05444283·Recruiting·Listed Jul 2022

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Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula

for Pancreatic Carcinoma

Sites in Chicago +17 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06807437·Phase 3·Recruiting·Listed Feb 2025

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Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial

for Prostate Adenocarcinoma

Drug: Relugolix

1 location in Chicago

Sponsor: Sean Sachdev

Sex: Male·Age: 18+

Code: NCT06499870·Phase 2·Recruiting·Listed Jul 2024

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Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

for Hypertensive Disorders of Pregnancy

Sites in Chicago +15 more locations

Sponsor: Ohio State University

Sex: Female·Age: 14 - 35

Code: NCT06468202·Phase 4·Recruiting·Listed Jun 2024

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The Gut and Skin Microbiome in Vitiligo Disease Progression

for Vitiligo

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT03577327·Recruiting·Listed Jul 2018

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My Wellbeing Guide: A Novel Tool for Managing Stress and Improving Quality of Life

for Cancer

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT05369429·Recruiting·Listed May 2022

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Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment)

for Ovary Cancer

1 location in Chicago

Sponsor: Northwestern University

Sex: Female·Age: 60+

Code: NCT05743517·Recruiting·Listed Feb 2023

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The COCOA-PAD II Trial

for Peripheral Artery Disease

Sites in Chicago +2 more locations

Sponsor: Northwestern University

Sex: All·Age: 55+

Code: NCT04794530·Phase 3·Recruiting·Listed Mar 2021

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Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke

for Stroke

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 21 - 100

Code: NCT04312269·Recruiting·Listed Mar 2020

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Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

for Obstetrical Complications

Sites in Chicago +13 more locations

Sponsor: The George Washington University Biostatistics Center

Sex: Female·Age: All ages·Accepts healthy volunteers

Code: NCT06605118·Phase 3·Recruiting·Listed Sep 2024

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Clinical Trial of Approaches to Prostate Cancer Surgery

for Prostate Cancer

Sites in Chicago +8 more locations

Sponsor: Weill Medical College of Cornell University

Sex: Male·Age: 40 - 80

Code: NCT05155501·Recruiting·Listed Dec 2021

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Segmentectomy After Induction Therapy (SAINT)

for Segmentectomy

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 89

Code: NCT06496659·Recruiting·Listed Jul 2024

Apply to this trial