Clinical Trials at Rush University Medical Center

As of August 2026, 133 paid clinical trials are recruiting at Rush University Medical Center, located at 1725 W HARRISON ST, NUMBER 1118 UNIVERSITY NEUROLOGISTS, CHICAGO, IL 60612-3841, phone (312) 942-5936 in Chicago, Illinois. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 27, 2026.

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135 clinical trials at Rush University Medical Center

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U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK Procedures

for Bone Tumor

Sites in Chicago +2 more locations

Sponsor: Precision IO Group

Sex: All·Age: 22+

Code: NCT07325578·Recruiting·Listed Jan 2026

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A Safety and Efficacy Study of GTX-102 in Subjects With Deletion- or Nondeletion-type Angelman Syndrome (AS)

for Angelman Syndrome

Sites in Chicago +7 more locations

Sponsor: Ultragenyx Pharmaceutical Inc

Sex: All·Age: 1 - 64

Code: NCT07157254·Phase 2·Recruiting·Listed Sep 2025

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Phase 1/2 Study of MZ-1866, an AAV-9 Gene Therapy Delivered by Intracerebroventricular Injection to Participants With Pitt Hopkins Syndrome

for Pitt Hopkins Syndrome

Sites in Chicago +2 more locations

Sponsor: Mahzi Therapeutics

Sex: All·Age: 2 - 25

Code: NCT07135050·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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Efficacy and Safety Study of TPX-115 on Partial-thickness Rotator Cuff Tear

for Partial Thickness Rotator Cuff Tears

Sites in Chicago +1 more location

Sponsor: Tego Science, Inc.

Sex: All·Age: 18+

Code: NCT07219654·Phase 2·Recruiting·Listed Oct 2025

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Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass

for Weight Regain

Sites in Chicago +8 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07015424·Recruiting·Listed Jun 2025

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MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion

for Degenerative Disc Disease

Sites in Chicago +7 more locations

Sponsor: Kuros Biosurgery AG

Sex: All·Age: 18+

Code: NCT05037968·Recruiting·Listed Sep 2021

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A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)

for Healthy Participants

Sites in Chicago +7 more locations

Sponsor: Equilibra Bioscience LLC

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06349473·Phase 1·Recruiting·Listed Apr 2024

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FiberLocker® System Augmentation of Rotator Cuff Repairs

for Rotator Cuff Tear

Sites in Chicago +3 more locations

Sponsor: ZuriMED Technologies Inc.

Sex: All·Age: 30 - 70

Code: NCT06918041·Recruiting·Listed Apr 2025

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International Multicentric Observational Study to Characterize Subpopulations of Patients With Autism Spectrum Disorder

for Autism Spectrum Disorder

Sites in Chicago +4 more locations

Sponsor: Stalicla SA

Sex: All·Age: 12 - 65

Code: NCT05590715·Recruiting·Listed Oct 2022

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Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study

for Obstructive Sleep Apnea (OSA)

Sites in Chicago +4 more locations

Sponsor: Inspire Medical Systems, Inc.

Sex: All·Age: 18+

Code: NCT07113288·Recruiting·Listed Aug 2025

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MOTION Clinical Trial

for Osteoarthritis, Knee

Sites in Chicago, Oak Brook +4 more locations

Sponsor: Moximed

Sex: All·Age: All ages

Code: NCT06843980·Recruiting·Listed Feb 2025

Apply to this trial

Non-Invasive Quantification of Liver Health in NASH (N-QUAN)

for NASH - Nonalcoholic Steatohepatitis

Sites in Chicago +5 more locations

Sponsor: Perspectum

Sex: All·Age: 18 - 75

Code: NCT04054310·Recruiting·Listed Aug 2019

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Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement

for Pain Management

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: Female·Age: 18+

Code: NCT07487246·Phase 2·Recruiting·Listed Mar 2026

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Mobilizing Community Hypertension Access Pilot

for Hypertension

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT07547345·Recruiting·Listed Apr 2026

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Nurse-Led PTSD Treatment in Primary Care

for Post Traumatic Stress Disorder PTSD

Sites in Chicago +1 more location

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT07430657·Recruiting·Listed Feb 2026

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PRImary Care Strategies for Weight Management (PRISM) Study

for Obesity

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT07288294·Recruiting·Listed Dec 2025

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Behavioral Economic Attributes of Recreation

for Cardiometabolic Health Indicators

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07282418·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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Comparing the Efficacy and Safety of Holmium Laser Lithotripsy Versus Electrohydraulic Lithotripsy for the Treatment of Difficult Choledocholithiasis and Pancreatic Duct Stones

for Choledocholithiasis

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 19 - 85

Code: NCT07418112·Phase 4·Recruiting·Listed Feb 2026

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The Impact of Skin Tone on Pulse Oximeter Accuracy

for Accuracy of Pulse Oximetry Across Skin Pigmentation Levels

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT07415187·Recruiting·Listed Feb 2026

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Chicago, Evanston +85 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

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Rapid Evacuation and Access of Cerebral Hemorrhage Trial

for Stroke Hemorrhagic

Sites in Chicago, Evanston +22 more locations

Sponsor: Emory University

Sex: All·Age: 18 - 70

Code: NCT06870812·Recruiting·Listed Mar 2025

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

Sites in Chicago, Maywood +111 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

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Rett Syndrome Registry

for Rett Syndrome

Sites in Chicago +18 more locations

Sponsor: International Rett Syndrome Foundation

Sex: All·Age: 0 - 99

Code: NCT05432349·Recruiting·Listed Jun 2022

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Molecular Genetics Studies of Cancer Patients and Their Relatives

for Malignant Neoplasm

Sites in Chicago +34 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04185935·Recruiting·Listed Dec 2019

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Proton or Photon RT for Retroperitoneal Sarcomas

for Retroperitoneal Sarcoma

Sites in Chicago +9 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT01659203·Phase 1, Phase 2·Recruiting·Listed Aug 2012

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

Sites in Chicago, North Chicago +89 more locations

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting·Listed Feb 2020

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Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

for Retroperitoneal Sarcoma

Sites in Chicago +96 more locations

Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All·Age: 18+

Code: NCT04031677·Phase 3·Recruiting·Listed Jul 2019

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ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

Sites in Chicago, Peoria +74 more locations

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting·Listed May 2020

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Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

for Hiv

Sites in Chicago +17 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06263426·Recruiting·Listed Feb 2024

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Operative vs Non-operative Management of Posterior-medial Meniscal Root Tears: A Randomized Multicenter Trial (RCT)

for Meniscus Tear, Tibial

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT05985772·Recruiting·Listed Aug 2023

Apply to this trial

Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection

for Osteoarthritis of the Knee

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18 - 70

Code: NCT05985785·Recruiting·Listed Aug 2023

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ROAM OA: Functional and Patient Reported Outcomes Wearing a Knee Brace for Unicompartmental OA

for Knee Osteoarthritis

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 40 - 85

Code: NCT07224958·Recruiting·Listed Nov 2025

Apply to this trial

Esomeprazole and Radiation Induced Esophagitis

for Radiation Esophagitis

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT06120803·Phase 2·Recruiting·Listed Nov 2023

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Hip Arthroscopy Postoperative Opioid Demands

for Opioid Use

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT04094701·Recruiting·Listed Sep 2019

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Resuscitative TEE Collaborative Registry

for Cardiac Arrest

1 location in Chicago

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04972526·Recruiting·Listed Jul 2021

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Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients

for Obesity, Morbid

Sites in Chicago, Winfield +2 more locations

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT05918575·Recruiting·Listed Jun 2023

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End Diagnostic Overshadowing

for Disabilities Multiple

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 3 - 89·Accepts healthy volunteers

Code: NCT06608758·Recruiting·Listed Sep 2024

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(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain

for Pain, Neuropathic

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18 - 75

Code: NCT05864053·Phase 1, Phase 2·Recruiting·Listed May 2023

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Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for Epiretinal Membrane

Sites in Chicago, Oak Park +45 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05145491·Recruiting·Listed Dec 2021

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Chicago, Maywood +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

Apply to this trial