Clinical Trials at Rush University Medical Center

As of July 2026, 139 paid clinical trials are recruiting at Rush University Medical Center, located at 1725 W HARRISON ST, NUMBER 1118 UNIVERSITY NEUROLOGISTS, CHICAGO, IL 60612-3841, phone (312) 942-5936 in Chicago, Illinois. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 16, 2026.

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139 clinical trials at Rush University Medical Center

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(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

for Advanced Systemic Mastocytosis (AdvSM)

14 locations incl. Birmingham

Sponsor: Cogent Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT04996875·Phase 2·Recruiting

Apply to this trial

Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)

for Pulmonary Embolism

10 locations incl. Irvine

Sponsor: Innova Vascular, Inc.

Sex: All·Age: 18 - 85

Code: NCT06041594·Recruiting

Apply to this trial

InSpace Accelerated Rehabilitation Study

for Rotator Cuff Tears

11 locations incl. Phoenix

Sponsor: Stryker Endoscopy

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT05329584·Recruiting

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A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A

for Haemophilia A

15 locations incl. Los Angeles

Sponsor: Novo Nordisk A/S

Sex: All·Age: All ages

Code: NCT05685238·Phase 3·Recruiting

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Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients

for Melanoma Stage IIIB

19 locations incl. Phoenix

Sponsor: Philogen S.p.A.

Sex: All·Age: 18+

Code: NCT03567889·Phase 3·Recruiting

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Non-Invasive Quantification of Liver Health in NASH (N-QUAN)

for NASH - Nonalcoholic Steatohepatitis

7 locations incl. Chandler

Sponsor: Perspectum

Sex: All·Age: 18 - 75

Code: NCT04054310·Recruiting

Apply to this trial

HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome

for Angelman Syndrome

6 locations incl. San Diego

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 0 - 50

Code: NCT05127226·Phase 1, Phase 2·Recruiting

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Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass

for Weight Regain

9 locations incl. Irvine

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07015424·Recruiting

Apply to this trial

Phase 1/2 Study of MZ-1866, an AAV-9 Gene Therapy Delivered by Intracerebroventricular Injection to Participants With Pitt Hopkins Syndrome

for Pitt Hopkins Syndrome

3 locations incl. Oakland

Sponsor: Mahzi Therapeutics

Sex: All·Age: 2 - 25

Code: NCT07135050·Phase 1, Phase 2·Recruiting

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A Safety and Efficacy Study of GTX-102 in Subjects With Deletion- or Nondeletion-type Angelman Syndrome (AS)

for Angelman Syndrome

8 locations incl. Los Angeles

Sponsor: Ultragenyx Pharmaceutical Inc

Sex: All·Age: 1 - 64

Code: NCT07157254·Phase 2·Recruiting

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FiberLocker® System Augmentation of Rotator Cuff Repairs

for Rotator Cuff Tear

4 locations incl. Chicago

Sponsor: ZuriMED Technologies Inc.

Sex: All·Age: 30 - 70

Code: NCT06918041·Recruiting

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MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion

for Degenerative Disc Disease

8 locations incl. Hartford

Sponsor: Kuros Biosurgery AG

Sex: All·Age: 18+

Code: NCT05037968·Recruiting

Apply to this trial

Efficacy and Safety Study of TPX-115 on Partial-thickness Rotator Cuff Tear

for Partial Thickness Rotator Cuff Tears

3 locations incl. La Mesa

Sponsor: Tego Science, Inc.

Sex: All·Age: 18+

Code: NCT07219654·Phase 2·Recruiting

Apply to this trial

U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK Procedures

for Bone Tumor

3 locations incl. San Diego

Sponsor: Precision IO Group

Sex: All·Age: 22+

Code: NCT07325578·Recruiting

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Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study

for Obstructive Sleep Apnea (OSA)

5 locations incl. Colorado Springs

Sponsor: Inspire Medical Systems, Inc.

Sex: All·Age: 18+

Code: NCT07113288·Recruiting

Apply to this trial

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)

for Healthy Participants

9 locations incl. Glendale

Sponsor: Equilibra Bioscience LLC

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06349473·Phase 1·Recruiting

Apply to this trial

Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea

for Obstructive Sleep Apnea of Adult

9 locations incl. Aurora

Sponsor: Cryosa, Inc.

Sex: All·Age: 22 - 70

Code: NCT06008626·Recruiting

Apply to this trial

International Multicentric Observational Study to Characterize Subpopulations of Patients With Autism Spectrum Disorder

for Autism Spectrum Disorder

9 locations incl. Phoenix

Sponsor: Stalicla SA

Sex: All·Age: 12 - 65

Code: NCT05590715·Recruiting

Apply to this trial

MOTION Clinical Trial

for Osteoarthritis, Knee

9 locations incl. Davis

Sponsor: Moximed

Sex: All·Age: All ages

Code: NCT06843980·Recruiting

Apply to this trial

A Validation Study to Evaluate the Performance of Caption Health Lung Guidance and Interpretation

for Shortness of Breath

4 locations incl. New Haven

Sponsor: Caption Health, Inc.

Sex: All·Age: 18+

Code: NCT05992324·Recruiting

Apply to this trial

External Sensing and Neuromodulation to Assess Diabetic Pain Outcomes (XANADO)

for Chronic Pain

1 location in Chicago

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT05537662·Recruiting

Apply to this trial

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

387 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting

Apply to this trial

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for Castration Levels of Testosterone

334 locations incl. Gilbert

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT03678025·Phase 3·Recruiting

Apply to this trial

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

142 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting

Apply to this trial

The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

93 locations incl. Phoenix

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting

Apply to this trial

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

for Retroperitoneal Sarcoma

109 locations incl. Birmingham

Sponsor: European Organisation for Research and Treatment of Cancer - EORTC

Sex: All·Age: 18+

Code: NCT04031677·Phase 3·Recruiting

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

187 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

102 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting

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Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery

for Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v6 and v7

140 locations incl. Tucson

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT03493425·Phase 2·Recruiting

Apply to this trial

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

for Huntington's Disease

62 locations incl. Birmingham

Sponsor: CHDI Foundation, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01574053·Recruiting

Apply to this trial

Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for Epiretinal Membrane

46 locations incl. Scottsdale

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05145491·Recruiting

Apply to this trial

Rett Syndrome Registry

for Rett Syndrome

19 locations incl. Birmingham

Sponsor: International Rett Syndrome Foundation

Sex: All·Age: 0 - 99

Code: NCT05432349·Recruiting

Apply to this trial

Molecular Genetics Studies of Cancer Patients and Their Relatives

for Malignant Neoplasm

35 locations incl. Phoenix

Sponsor: City of Hope Medical Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04185935·Recruiting

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Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

for Hiv

18 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06263426·Recruiting

Apply to this trial

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

for Chronic Obstructive Pulmonary Disease (COPD)

Drug: Omalizumab

23 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 40+

Code: NCT07059091·Phase 2·Recruiting

Apply to this trial

Preoperative Fasting vs. Not Fasting in Critically Ill Patients

for Critical Illness

19 locations incl. Palo Alto

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06751043·Recruiting

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RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

for Osteoporosis

23 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50+

Code: NCT06455085·Recruiting

Apply to this trial

His-Bundle Corrective Pacing in Heart Failure

for Right Bundle-Branch Block

14 locations incl. Phoenix

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05265520·Recruiting

Apply to this trial

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

71 locations incl. Phoenix

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting

Apply to this trial

Trial of Therapeutic Hypothermia in Patients With ARDS

for Respiratory Distress Syndrome, Adult

19 locations incl. Los Angeles

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 85

Code: NCT04545424·Phase 2·Recruiting

Apply to this trial