Clinical Trials at University of Chicago

As of August 2026, 171 paid clinical trials are recruiting at University of Chicago, located at 5841 S MARYLAND AVE # 2115, CHICAGO, IL 60637-1447, phone (773) 702-4601 in Chicago, Illinois. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 27, 2026.

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174 clinical trials at University of Chicago

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Accelerometer Measured Early Recovery After Prolapse Surgery

for Pelvic Organ Prolapse

Sites in Chicago +6 more locations

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 18 - 99

Code: NCT07218016·Recruiting·Listed Oct 2025

Apply to this trial

Case Management Dyad

for HIV

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06162897·Recruiting·Listed Dec 2023

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Tibial IMN Vs. Tibial Micromotion IMN

for Tibial Fracture

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06976801·Recruiting·Listed May 2025

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Let's E.A.T.! (Eating With Assistive Technology): An Intervention to Support Children With Feeding Tubes and Tracheostomies

for Feeding Tube

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: Up to 3

Code: NCT06525818·Recruiting·Listed Jul 2024

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Does Ethyl Chloride Spray Work?

for Injection Fear

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06651788·Recruiting·Listed Oct 2024

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Oxygenation in Vascular Lesions of the Colon

for Vascular Lesion

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT06230731·Recruiting·Listed Jan 2024

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Achieving Routine Intervention and Screening for Emotional Health

for Type 2 Diabetes Mellitus (T2DM)

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT06887049·Recruiting·Listed Mar 2025

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International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

Sites in Chicago, Warrenville +33 more locations

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting·Listed May 2017

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Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer

for Estrogen-receptor-positive Breast Cancer

3 locations in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06062498·Phase 2·Recruiting·Listed Oct 2023

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Tocilizumab for Acute Chest Syndrome

for Sickle Cell Disease

Drug: Tocilizumab

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 12+

Code: NCT05640271·Phase 2·Recruiting·Listed Dec 2022

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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

Sites in Chicago, Maywood +31 more locations

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting·Listed Jan 2010

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Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer

for Gastric Cancer

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT04107077·Phase 2·Recruiting·Listed Sep 2019

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A Study of the Natural Progression of Interstitial Lung Disease (ILD)

for Interstitial Lung Diseases

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00470327·Recruiting·Listed May 2007

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Intrathecal Morphine for Analgesia in Video-assisted and Robotic-assisted Thoracic Surgery

for Pain, Postoperative

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 80

Code: NCT05351229·Phase 4·Recruiting·Listed Apr 2022

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Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis

for Graft Vs Host Disease

Sites in Chicago +3 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 2+

Code: NCT04380740·Phase 2·Recruiting·Listed May 2020

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CLOZAPINE Response in Biotype-1

for Schizophrenia

Sites in Chicago +4 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 60

Code: NCT04580134·Phase 4·Recruiting·Listed Oct 2020

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Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence

for Stress Urinary Incontinence

Sites in Chicago +6 more locations

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 21+

Code: NCT06480227·Recruiting·Listed Jun 2024

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Genomic Predictors of Recurrent Pregnancy Loss

for Recurrent Pregnancy Loss

Sites in Chicago +8 more locations

Sponsor: Yale University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05444283·Recruiting·Listed Jul 2022

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Self-sampling to Optimize Anal Lesion Outcomes

for Anal Cancer

Sites in Chicago +2 more locations

Sponsor: Medical College of Wisconsin

Sex: All·Age: 35+·Accepts healthy volunteers

Code: NCT07192055·Recruiting·Listed Sep 2025

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The COCOA-PAD II Trial

for Peripheral Artery Disease

Sites in Chicago +2 more locations

Sponsor: Northwestern University

Sex: All·Age: 55+

Code: NCT04794530·Phase 3·Recruiting·Listed Mar 2021

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Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

Sites in Chicago +18 more locations

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting·Listed Jul 2023

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Cortical Recording and Stimulating Array Brain-Machine Interface

for Tetraplegia

Sites in Chicago +1 more location

Sponsor: Michael Boninger

Sex: All·Age: 22 - 70

Code: NCT01894802·Recruiting·Listed Jul 2013

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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for Heart Diseases

Sites in Chicago +40 more locations

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT04124120·Recruiting·Listed Oct 2019

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Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

for Endometrial Cancer

Sites in Chicago +19 more locations

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT05051722·Recruiting·Listed Sep 2021

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Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

for Neurofibromatosis 1

Drug: Selumetinib

Sites in Chicago +14 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 - 8

Code: NCT06188741·Phase 2·Recruiting·Listed Jan 2024

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AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia

for Community-acquired Pneumonia

Sites in Chicago +4 more locations

Sponsor: University of Manitoba

Sex: All·Age: 18+

Code: NCT05848713·Phase 3·Recruiting·Listed May 2023

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Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss

for Peripheral Artery Disease

Sites in Chicago +5 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT04228978·Recruiting·Listed Jan 2020

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BEETroot Juice to Reverse Functional Impairment in PAD

for Peripheral Artery Disease

Sites in Chicago +2 more locations

Sponsor: Northwestern University

Sex: All·Age: 50+

Code: NCT05624125·Recruiting·Listed Nov 2022

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Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

Sites in Chicago +24 more locations

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting·Listed Jun 2023

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Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast Cancer

for Breast Cancer

Sites in Chicago +6 more locations

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04841148·Phase 2·Recruiting·Listed Apr 2021

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Early PKD Observational Cohort Study

for Polycystic Kidney Disease

Sites in Chicago +2 more locations

Sponsor: University of Kansas Medical Center

Sex: All·Age: 4 - 35·Accepts healthy volunteers

Code: NCT02936791·Recruiting·Listed Oct 2016

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J-RISE: Relevant Implementation Strategies to Eliminate the Social and Structural Barriers to HIV Services Among Justice-involved Black Men Who Have Sex With Men and Other Key Populations

for HIV

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06477588·Recruiting·Listed Jun 2024

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SMART Exercise for PAD

for Peripheral Arterial Disease

Sites in Chicago +2 more locations

Sponsor: Northwestern University

Sex: All·Age: 50+

Code: NCT06032065·Phase 3·Recruiting·Listed Sep 2023

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Work2Prevent Plus: Structural Intervention to Promote HIV Care in Black Sexual Minority Men

for HIV

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06894199·Recruiting·Listed Mar 2025

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Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas

for Salivary Gland Cancer

Sites in Chicago +12 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04620187·Phase 2·Recruiting·Listed Nov 2020

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Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

for Parkinson Disease

Sites in Chicago +10 more locations

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06719583·Recruiting·Listed Dec 2024

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Stroke Thrombectomy and Aneurysm Registry

for Stroke

Sites in Chicago, Evanston +52 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting·Listed Aug 2021

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STOP-UC: De-escalation of Therapy in Patients With Ulcerative Colitis With Histological Remission

for Ulcerative Colitis (UC)

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 75

Code: NCT06693310·Recruiting·Listed Nov 2024

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The APS Phenotyping Study

for ARDS

Sites in Chicago +19 more locations

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06521502·Recruiting·Listed Jul 2024

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His-Bundle Corrective Pacing in Heart Failure

for Right Bundle-Branch Block

Sites in Chicago +13 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05265520·Recruiting·Listed Mar 2022

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